|
rs1217691063
|
|
Coronary Artery Disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
Methylenetetrahydrofolate reductase 677 C-->T mutation and coronary heart disease risk in UK Indian Asians.
|
11073851 |
2000 |
|
rs1217691063
|
|
Coronary Artery Disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
Methylenetetrahydrofolate reductase polymorphism (MTHFR C677T) is an established determinant of homocysteine plasma level (t-Hcys) while its association with coronary artery disease (CAD) seems to be more limited.
|
16268464 |
2005 |
|
rs1217691063
|
|
Coronary Artery Disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
MTHFR 677 C-->T mutation: a predictor of early-onset coronary artery disease risk.
|
11562338 |
2001 |
|
rs1217691063
|
|
Coronary Artery Disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
MTHFR 677C-->T polymorphism and risk of coronary heart disease: a meta-analysis.
|
12387655 |
2002 |
|
rs1217691063
|
|
Coronary Artery Disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
MTHFR C677T, but not A1298C SNPs, is associated with CAD and with elevated homocysteine levels in a Tunisian population.
|
18204887 |
2009 |
|
rs1217691063
|
|
Coronary Artery Disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
MTHFR C677T polymorphism, and GpIIIa and PAI-1 genes are risk factors for CAD.
|
27805237 |
2017 |
|
rs1217691063
|
|
Coronary Artery Disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
Mutation C677T of methylenetetrahydrofolate reductase gene is not associated with coronary artery disease, but possibly with albuminuria, in type 2 diabetic patients.
|
9806473 |
1998 |
|
rs1217691063
|
|
Coronary Artery Disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
No strong evidence exists to support an association of the MTHFR 677 C-->T polymorphism and coronary heart disease in Europe, North America, or Australia.
|
16216822 |
2005 |
|
rs1217691063
|
|
Coronary Artery Disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
One putative determinant of PAD is the 677C>T polymorphism in the gene encoding methylenetetrahydrofolate reductase (MTHFR), which has previously been found to associate with various diabetic complications including retinopathy, nephropathy, atherosclerosis and coronary heart disease.
|
16274479 |
2005 |
|
rs1217691063
|
|
Coronary Artery Disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
Our data suggest that there is no association between the C677T mutation of the human MTHFR gene and the risk of CAD or VT among Chinese in Taiwan.
|
11096270 |
2001 |
|
rs1217691063
|
|
Coronary Artery Disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
Patients with angiographic evidence of CAD or clinical MI do not show an increased frequency of the C677T transition in the MTHFR gene.
|
9350916 |
1997 |
|
rs1217691063
|
|
Coronary Artery Disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
Plasma homocysteine levels & 677C-->T methylenetetrahydrofolate reductase gene polymorphism in patients with coronary artery disease of different severity.
|
18403793 |
2008 |
|
rs1217691063
|
|
Coronary Artery Disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
Prothrombin G20210A, FV Leiden and MTHFR C677T mutations, protein C, S and AT-III deficiencies did not increase the risk of CAD in our young population.
|
18176672 |
2008 |
|
rs1217691063
|
|
Coronary Artery Disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
Recent studies have shown that a common mutation (nucleotide 677 C-->T) in the methylenetetrahydrofolate reductase (MTHFR) gene may contribute to mild hyperhomocysteinemia and, therefore, to the incidence of coronary artery disease.
|
11319193 |
2001 |
|
rs1217691063
|
|
Coronary Artery Disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
Recent studies have shown that a common mutation (nucleotide 677 C-->T) in the methylenetetrahydrofolate reductase (MTHFR) gene may contribute to a mild rise in plasma homocysteine levels and increase the incidence of coronary artery disease.
|
16489563 |
2006 |
|
rs1217691063
|
|
Coronary Artery Disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
Role of homocysteine & MTHFR C677T gene polymorphism as risk factors for coronary artery disease in young Indians.
|
22664498 |
2012 |
|
rs1217691063
|
|
Coronary Artery Disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
The 5,10-methylenetetrahydrofolate reductase gene (MTHFR) 677C-->T polymorphism modifies the risk of coronary artery disease and colon cancer and is related to plasma concentrations of total homocysteine (tHcy).
|
15447919 |
2004 |
|
rs1217691063
|
|
Coronary Artery Disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
The C677T mutation in methylenetetrahydrofolate reductase gene, plasma homocysteine concentration and the risk of coronary artery disease.
|
14560345 |
2003 |
|
rs1217691063
|
|
Coronary Artery Disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
The C677T polymorphism of the MTHFR gene is associated with hyperhomocysteinaemia, lipid dysregulation and the presence of CAD in this Tunisian Arab population.
|
16704755 |
2006 |
|
rs1217691063
|
|
Coronary Artery Disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
The C677T mutation in the methylenetetrahydrofolate reductase (MTHFR) gene is associated with early onset of coronary artery disease in some populations with certain ethnic backgrounds.
|
18751630 |
2008 |
|
rs1217691063
|
|
Coronary Artery Disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
The C677T polymorphism of 5,10 methylenetetrahydrofolate reductase (MTHFR) gene has been associated with hypertension and coronary artery disease in several populations worldwide, but results are still controversial.
|
20637366 |
2010 |
|
rs1217691063
|
|
Coronary Artery Disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
The aim of this work was to analyze the frequency of methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism in patients with CAD and its association with plasma homocysteine levels.
|
17505678 |
2007 |
|
rs1217691063
|
|
Coronary Artery Disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
The association of MTHFR C677T gene variants and lipid profiles or body mass index in patients with diabetic and nondiabetic coronary heart disease.
|
24218123 |
2013 |
|
rs1217691063
|
|
Coronary Artery Disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
The homozygous C677T genotype has previously been associated with coronary heart disease in Ireland.
|
9974399 |
1999 |
|
rs1217691063
|
|
Coronary Artery Disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
The objective of our study is to evaluate the single locus and combined effects of three different genetic polymorphisms (methylenetetrahydrofolate reductase C677T polymorphism, plasminogen activator inhibitor 4G/5G polymorphism, and endothelial nitric oxide synthase 3-27 base pairs repeat polymorphism) on the presence and extent of coronary artery disease in patients with early-onset coronary artery disease.
|
16845248 |
2006 |