rs28362491
|
|
Malignant Neoplasms
|
|
0.060 |
GeneticVariation
|
BEFREE |
Numerous studies have addressed the association of a functional insertion (I)/deletion (D) polymorphism (-94ins/delATTG, rs28362491) in the promoter region of NFKB1 gene with the risk of various types of cancer; however, their conclusions have been inconsistent.
|
28039461 |
2017 |
rs28362491
|
|
Malignant Neoplasms
|
|
0.060 |
GeneticVariation
|
BEFREE |
A functional -94 insertion/deletion ATTG polymorphism (rs28362491) in the promoter of the NFKB1 gene was reported to affect NF-KB1 expression and confer susceptibility to different types of cancer.
|
26835711 |
2016 |
rs28362491
|
|
Malignant Neoplasms
|
|
0.060 |
GeneticVariation
|
BEFREE |
The 94ins/del ATTG (rs28362491) polymorphism located in the NFKB1 gene has been associated to various cancers and the ATTG2/ATTG2 genotype was correlated to melanoma risk in Sweden.
|
27145040 |
2016 |
rs28362491
|
|
Malignant Neoplasms
|
|
0.060 |
GeneticVariation
|
BEFREE |
A functional -94 insertion/deletion polymorphism (rs28362491) in the promoter of the NF-κ B1 gene was reported to influence NF-κ B1 expression and confer susceptibility to different types of cancer.
|
26484607 |
2016 |
rs28362491
|
|
Malignant Neoplasms
|
|
0.060 |
GeneticVariation
|
BEFREE |
A functional -94 insertion/deletion polymorphism (rs28362491) in the promoter of the NFKB1 gene was reported to influence NFKB1 expression and confer susceptibility to different types of cancer.
|
23977085 |
2013 |
rs28362491
|
|
Malignant Neoplasms
|
|
0.060 |
GeneticVariation
|
BEFREE |
Recently, a common insertion/deletion (-94insertion/deletion ATTG, rs28362491) polymorphism in the NFkappaB1 promoter region has been extensively investigated for association with cancer risk but the results have been inconsistent.
|
22320942 |
2011 |
rs28362491
|
|
Primary malignant neoplasm
|
|
0.050 |
GeneticVariation
|
BEFREE |
Numerous studies have addressed the association of a functional insertion (I)/deletion (D) polymorphism (-94ins/delATTG, rs28362491) in the promoter region of NFKB1 gene with the risk of various types of cancer; however, their conclusions have been inconsistent.
|
28039461 |
2017 |
rs28362491
|
|
Primary malignant neoplasm
|
|
0.050 |
GeneticVariation
|
BEFREE |
A functional -94 insertion/deletion ATTG polymorphism (rs28362491) in the promoter of the NFKB1 gene was reported to affect NF-KB1 expression and confer susceptibility to different types of cancer.
|
26835711 |
2016 |
rs28362491
|
|
Primary malignant neoplasm
|
|
0.050 |
GeneticVariation
|
BEFREE |
A functional -94 insertion/deletion polymorphism (rs28362491) in the promoter of the NF-κ B1 gene was reported to influence NF-κ B1 expression and confer susceptibility to different types of cancer.
|
26484607 |
2016 |
rs28362491
|
|
Primary malignant neoplasm
|
|
0.050 |
GeneticVariation
|
BEFREE |
A functional -94 insertion/deletion polymorphism (rs28362491) in the promoter of the NFKB1 gene was reported to influence NFKB1 expression and confer susceptibility to different types of cancer.
|
23977085 |
2013 |
rs28362491
|
|
Primary malignant neoplasm
|
|
0.050 |
GeneticVariation
|
BEFREE |
Recently, a common insertion/deletion (-94insertion/deletion ATTG, rs28362491) polymorphism in the NFkappaB1 promoter region has been extensively investigated for association with cancer risk but the results have been inconsistent.
|
22320942 |
2011 |
rs28362491
|
|
Coronary Artery Disease
|
|
0.040 |
GeneticVariation
|
BEFREE |
Association Between the NFKB1-94ins/del ATTG Polymorphism (rs28362491) and Coronary Artery Disease: A Systematic Review and Meta-Analysis.
|
26799199 |
2016 |
rs28362491
|
|
Coronary Artery Disease
|
|
0.040 |
GeneticVariation
|
BEFREE |
The genotype and allele frequencies of the rs28362491 (promoter region) polymorphism in the CAD patients were significantly different from those in the healthy controls.
|
27525877 |
2016 |
rs28362491
|
|
Coronary Artery Disease
|
|
0.040 |
GeneticVariation
|
BEFREE |
Significant difference in the frequency of genotypes (P = 0.001) and alleles (P = 0.001) of rs28362491</span> polymorphism was observed in CAD cases compared to controls.
|
26075620 |
2015 |
rs28362491
|
|
Coronary Artery Disease
|
|
0.040 |
GeneticVariation
|
BEFREE |
The DD genotype of the SNP (rs28362491) in the NFKB1 gene may be considered a genetic marker of CAD in Han and Uygur women in China.
|
24818816 |
2014 |
rs28362491
|
|
Hepatitis C
|
|
0.030 |
GeneticVariation
|
BEFREE |
Besides normal routine laboratory testing for HCV, patients' sera were evaluated also for retinol, retinol-binding protein 4 and the following SNPs: PNPLA3 (rs738409), TM6SF2 (rs58542926), MBOAT7 (rs641738), IL28B (rs12979860), TIMP-1 (rs4898), TIMP-2 (rs8179090), NF-kB promoter (rs28362491).
|
31826071 |
2019 |
rs28362491
|
|
Hepatitis C
|
|
0.030 |
GeneticVariation
|
BEFREE |
NFKB1 rs28362491-D allele was functionally associated with the increased risk of susceptibility to HCV infection in the Chinese Han population.
|
30056167 |
2018 |
rs28362491
|
|
Colorectal Carcinoma
|
|
0.030 |
GeneticVariation
|
BEFREE |
One of these markers (rs28362491) and the marker in the <i>UGT1A1</i> gene (rs8175347) were positively associated with the development of CRC.
|
29358861 |
2017 |
rs28362491
|
|
Hepatitis C
|
|
0.030 |
GeneticVariation
|
BEFREE |
The present study aims to evaluate the association between -94Ins/DelATTG (rs28362491) polymorphism in NF-κB1 gene promoter region and 2758G>A (rs696) single nucleotide polymorphism in the 3'UTR region of NFκBIA and the outcomes of HCV infection.
|
26827631 |
2016 |
rs28362491
|
|
Colorectal Carcinoma
|
|
0.030 |
GeneticVariation
|
BEFREE |
Del-carriers of the NFKB1/rs28362491 polymorphism had a 17% (95%CI: 1.03-1.34; P = 0.02) increased risk of CRC compared to homozygous carriers of the ins-allele.
|
25705893 |
2015 |
rs28362491
|
|
Colorectal Carcinoma
|
|
0.030 |
GeneticVariation
|
BEFREE |
The variant allele of NFKB1 -94 ins/del ATTG (rs28362491) polymorphism is associated with higher risk of sporadic CRC in Malaysian population.
|
23806437 |
2013 |
rs4648068
|
|
Stomach Carcinoma
|
|
0.030 |
GeneticVariation
|
BEFREE |
Quantitative real-time PCR was used to detect NFKB1 SNP rs4648068 genotype in the patients with gastric cancer.
|
25888547 |
2015 |
rs4648068
|
|
Malignant neoplasm of stomach
|
|
0.030 |
GeneticVariation
|
BEFREE |
Quantitative real-time PCR was used to detect NFKB1 SNP rs4648068 genotype in the patients with gastric cancer.
|
25888547 |
2015 |
rs4648068
|
|
Malignant neoplasm of stomach
|
|
0.030 |
GeneticVariation
|
BEFREE |
The allelic or genotypic frequencies of the rs28362491 (located in the promoter region of NFKB1), rs230521 (NFKB1 intron 4), and rs4648068 (NFKB1 intron 12) polymorphisms in the patients with GC were significantly different from those in the healthy controls.
|
25526460 |
2014 |
rs4648068
|
|
Stomach Carcinoma
|
|
0.030 |
GeneticVariation
|
BEFREE |
The allelic or genotypic frequencies of the rs28362491 (located in the promoter region of NFKB1), rs230521 (NFKB1 intron 4), and rs4648068 (NFKB1 intron 12) polymorphisms in the patients with GC were significantly different from those in the healthy controls.
|
25526460 |
2014 |