Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7157
Gene Symbol: TP53
TP53 		P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.120 None 1.000 2 3 2010 2019
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR 		P42898 methylenetetrahydrofolate reductase 985 0.337 0.885 3.2E-10 0.050 None 1.000 5 2 1998 2012
Entrez Id: 2717
Gene Symbol: GLA
GLA 		P06280 galactosidase alpha 190 0.537 0.769 1.00 0.110 None 1.000 1 2 2010 2010
Entrez Id: 6934
Gene Symbol: TCF7L2
TCF7L2 		Q9NQB0 transcription factor 7 like 2 257 0.485 0.846 1.00 0.010 None 1.000 1 1 2011 2011
Entrez Id: 4193
Gene Symbol: MDM2
MDM2 		Q00987 MDM2 proto-oncogene Nucleic acid binding 702 0.362 0.846 1.00 0.200 None 1.000 1 1 2014 2014
Entrez Id: 4160
Gene Symbol: MC4R
MC4R 		P32245 melanocortin 4 receptor G-protein coupled receptor 149 0.535 0.692 9.2E-04 0.010 None 1.000 1 1 2011 2011
Entrez Id: 5345
Gene Symbol: SERPINF2
SERPINF2 		P08697 serpin family F member 2 Enzyme modulator 104 0.575 0.808 1.4E-02 0.010 None 1.000 1 1 2019 2019
Entrez Id: 225
Gene Symbol: ABCD2
ABCD2 		Q9UBJ2 ATP binding cassette subfamily D member 2 Transporter 25 0.711 0.500 4.7E-06 0.070 None 1.000 7 0 2017 2018
Entrez Id: 1557
Gene Symbol: CYP2C19
CYP2C19 		P33261 cytochrome P450 family 2 subfamily C member 19 274 0.467 0.846 6.5E-20 0.060 None 1.000 6 0 2014 2019
Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2 		Q16236 nuclear factor, erythroid 2 like 2 Enzyme 823 0.357 0.885 3.6E-03 0.050 None 1.000 5 0 2018 2019
Entrez Id: 2551
Gene Symbol: GABPA
GABPA 		Q06546 GA binding protein transcription factor subunit alpha Transcription factor 632 0.379 0.885 1.00 0.050 None 1.000 5 0 2018 2019
Entrez Id: 348
Gene Symbol: APOE
APOE 		P02649 apolipoprotein E 1049 0.338 0.962 1.9E-03 0.240 None 1.000 5 0 2000 2014
Entrez Id: 5468
Gene Symbol: PPARG
PPARG 		P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 877 0.358 0.885 2.9E-02 0.220 None 1.000 5 0 2008 2019
Entrez Id: 4318
Gene Symbol: MMP9
MMP9 		P14780 matrix metallopeptidase 9 Enzyme 1337 0.305 0.923 1.9E-17 0.220 None 1.000 5 0 2001 2017
Entrez Id: 7124
Gene Symbol: TNF
TNF 		P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.220 None 0.750 4 0 2001 2018
Entrez Id: 6647
Gene Symbol: SOD1
SOD1 		P00441 superoxide dismutase 1 Enzyme 689 0.379 0.962 0.18 0.300 None 1.000 4 0 2003 2007
Entrez Id: 596
Gene Symbol: BCL2
BCL2 		P10415 BCL2 apoptosis regulator Signaling 1456 0.291 0.885 0.56 0.200 None 1.000 3 0 2006 2012
Entrez Id: 1728
Gene Symbol: NQO1
NQO1 		P15559 NAD(P)H quinone dehydrogenase 1 368 0.434 0.885 1.2E-09 0.200 None 1.000 3 0 2017 2017
Entrez Id: 842
Gene Symbol: CASP9
CASP9 		P55211 caspase 9 Enzyme 293 0.458 0.808 7.4E-06 0.500 None 1.000 3 0 2001 2011
Entrez Id: 58157
Gene Symbol: NGB
NGB 		Q9NPG2 neuroglobin Transporter 56 0.631 0.462 4.5E-03 0.200 None 1.000 3 0 2003 2012
Entrez Id: 1401
Gene Symbol: CRP
CRP 		P02741 C-reactive protein 1483 0.299 0.962 3.7E-03 0.030 None 1.000 3 0 2007 2019
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1 		P38398 BRCA1 DNA repair associated Enzyme 747 0.367 0.923 9.2E-29 0.030 None 1.000 3 0 2017 2018
Entrez Id: 6774
Gene Symbol: STAT3
STAT3 		P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1193 0.320 0.923 1.00 0.210 None 1.000 3 0 2013 2017
Entrez Id: 7450
Gene Symbol: VWF
VWF 		P04275 von Willebrand factor Enzyme modulator 498 0.408 0.885 3.2E-25 0.220 None 1.000 3 0 2012 2019
Entrez Id: 2147
Gene Symbol: F2
F2 		P00734 coagulation factor II, thrombin Enzyme 490 0.415 0.885 1.1E-03 0.030 None 1.000 3 0 1998 2005