Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 324
Gene Symbol: APC
APC 		P25054 APC regulator of WNT signaling pathway 703 0.373 0.962 1.00 0.600 None 0.949 39 6 1990 2019
Entrez Id: 5395
Gene Symbol: PMS2
PMS2 		P54278 PMS1 homolog 2, mismatch repair system component Nucleic acid binding 244 0.484 0.808 4.5E-27 0.010 None < 0.001 1 5 2004 2004
Entrez Id: 7157
Gene Symbol: TP53
TP53 		P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.500 None 0.969 64 4 1986 2019
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		P00533 epidermal growth factor receptor Kinase 1394 0.295 0.885 0.37 0.400 None 1.000 18 4 1991 2018
Entrez Id: 673
Gene Symbol: BRAF
BRAF 		P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1228 0.319 0.846 1.00 0.200 None 0.952 21 2 2003 2019
Entrez Id: 4292
Gene Symbol: MLH1
MLH1 		P40692 mutL homolog 1 Nucleic acid binding 526 0.399 0.808 3.4E-05 0.400 None 0.947 19 2 1994 2017
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR 		P42898 methylenetetrahydrofolate reductase 985 0.337 0.885 3.2E-10 0.370 None 1.000 8 2 2001 2011
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1 		P08183 ATP binding cassette subfamily B member 1 Transporter 933 0.344 0.885 1.3E-05 0.070 None 0.714 7 2 1994 2008
Entrez Id: 2321
Gene Symbol: FLT1
FLT1 		P17948 fms related receptor tyrosine kinase 1 Kinase 424 0.419 0.846 1.00 0.010 None 1.000 1 2 2014 2014
Entrez Id: 51422
Gene Symbol: PRKAG2
PRKAG2 		Q9UGJ0 protein kinase AMP-activated non-catalytic subunit gamma 2 Enzyme modulator 122 0.582 0.654 1.00 0.010 None 1.000 1 2 2010 2010
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		P01116 KRAS proto-oncogene, GTPase Enzyme modulator 1213 0.320 0.923 7.9E-04 0.400 None 0.971 35 1 1987 2018
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		P15692 vascular endothelial growth factor A Signaling 1899 0.266 0.923 2.4E-05 0.400 None 0.950 20 1 1999 2019
Entrez Id: 4436
Gene Symbol: MSH2
MSH2 		P43246 mutS homolog 2 Nucleic acid binding 490 0.406 0.808 0.90 0.100 None 1.000 11 1 1994 2018
Entrez Id: 6790
Gene Symbol: AURKA
AURKA 		O14965 aurora kinase A Kinase 245 0.475 0.731 0.87 0.030 None 1.000 3 1 1998 2005
Entrez Id: 2065
Gene Symbol: ERBB3
ERBB3 		P21860 erb-b2 receptor tyrosine kinase 3 Kinase 318 0.448 0.808 1.7E-15 0.110 None 1.000 2 1 2012 2013
Entrez Id: 7517
Gene Symbol: XRCC3
XRCC3 		O43542 X-ray repair cross complementing 3 184 0.505 0.769 1.9E-10 0.010 None 1.000 1 1 2011 2011
Entrez Id: 8189
Gene Symbol: SYMPK
SYMPK 		Q92797 symplekin 39 0.700 0.231 1.00 0.100 None 1.000 1 1 2017 2017
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1 		P35222 catenin beta 1 1368 0.303 0.885 1.00 0.400 None 1.000 38 0 1998 2017
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2 		P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1234 0.314 0.962 1.00 0.600 None 1.000 35 0 1996 2019
Entrez Id: 168400
Gene Symbol: DDX53
DDX53 		Q86TM3 DEAD-box helicase 53 117 0.568 0.846 0.66 0.100 None 1.000 19 0 2004 2019
Entrez Id: 5468
Gene Symbol: PPARG
PPARG 		P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 877 0.358 0.885 2.9E-02 0.400 None 0.923 13 0 2003 2010
Entrez Id: 1026
Gene Symbol: CDKN1A
CDKN1A 		P38936 cyclin dependent kinase inhibitor 1A 490 0.403 0.769 1.9E-03 0.400 None 1.000 12 0 2002 2010
Entrez Id: 7298
Gene Symbol: TYMS
TYMS 		P04818 thymidylate synthetase Enzyme 406 0.425 0.846 0.72 0.360 None 1.000 12 0 1988 2008
Entrez Id: 1048
Gene Symbol: CEACAM5
CEACAM5 		P06731 CEA cell adhesion molecule 5 428 0.420 0.846 4.2E-10 0.100 None 1.000 11 0 1983 2019
Entrez Id: 960
Gene Symbol: CD44
CD44 		P16070 CD44 molecule (Indian blood group) 711 0.363 0.962 2.4E-07 0.100 None 1.000 10 0 1995 2018