Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 240
Gene Symbol: ALOX5
ALOX5
P09917 arachidonate 5-lipoxygenase Enzyme 342 0.447 0.885 1.2E-06 0.310 None 1.000 1 0 2008 2008
Entrez Id: 3611
Gene Symbol: ILK
ILK
Q13418 integrin linked kinase Kinase 192 0.503 0.769 3.8E-05 0.300 None 1.000 1 0 2001 2001
Entrez Id: 54822
Gene Symbol: TRPM7
TRPM7
Q96QT4 transient receptor potential cation channel subfamily M member 7 Ion channel 151 0.531 0.731 5.2E-16 0.300 None 1.000 1 0 2007 2007
Entrez Id: 3066
Gene Symbol: HDAC2
HDAC2
Q92769 histone deacetylase 2 Epigenetic regulator 257 0.476 0.846 1.00 0.200 None 1.000 1 0 2014 2014
Entrez Id: 5395
Gene Symbol: PMS2
PMS2
P54278 PMS1 homolog 2, mismatch repair system component Nucleic acid binding 244 0.484 0.808 4.5E-27 0.110 None 1.000 1 1 2008 2008
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
P60484 phosphatase and tensin homolog Enzyme 1349 0.305 0.923 0.26 0.100 None 0 1
Entrez Id: 5468
Gene Symbol: PPARG
PPARG
P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 877 0.358 0.885 2.9E-02 0.050 None 0.800 5 0 2002 2010
Entrez Id: 324
Gene Symbol: APC
APC
P25054 APC regulator of WNT signaling pathway 703 0.373 0.962 1.00 0.050 None 1.000 5 2 1997 2013
Entrez Id: 1045
Gene Symbol: CDX2
CDX2
Q99626 caudal type homeobox 2 Transcription factor 278 0.458 0.769 0.53 0.050 None 1.000 5 0 2002 2011
Entrez Id: 4255
Gene Symbol: MGMT
MGMT
P16455 O-6-methylguanine-DNA methyltransferase 444 0.412 0.885 1.2E-07 0.030 None 1.000 3 0 2011 2016
Entrez Id: 3479
Gene Symbol: IGF1
IGF1
P05019 insulin like growth factor 1 1206 0.318 0.885 0.27 0.030 None 1.000 3 0 2002 2019
Entrez Id: 673
Gene Symbol: BRAF
BRAF
P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1228 0.319 0.846 1.00 0.030 None 1.000 3 0 2016 2017
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.030 None 1.000 3 0 2001 2018
Entrez Id: 4292
Gene Symbol: MLH1
MLH1
P40692 mutL homolog 1 Nucleic acid binding 526 0.399 0.808 3.4E-05 0.030 None 1.000 3 0 2004 2007
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
P35222 catenin beta 1 1368 0.303 0.885 1.00 0.030 None 1.000 3 0 2008 2010
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
P01116 KRAS proto-oncogene, GTPase Enzyme modulator 1213 0.320 0.923 7.9E-04 0.020 None 1.000 2 0 2011 2017
Entrez Id: 780897
Gene Symbol: HPP1
HPP1
hyperpigmentation, progressive, 1 35 0.686 0.346 0.010 None 1.000 1 0 2002 2002
Entrez Id: 57007
Gene Symbol: ACKR3
ACKR3
P25106 atypical chemokine receptor 3 G-protein coupled receptor 400 0.428 0.885 0.39 0.010 None 1.000 1 0 2014 2014
Entrez Id: 8864
Gene Symbol: PER2
PER2
O15055 period circadian regulator 2 Transcription factor 238 0.488 0.846 0.71 0.010 None 1.000 1 0 2008 2008
Entrez Id: 9365
Gene Symbol: KL
KL
Q9UEF7 klotho Enzyme 332 0.448 0.769 2.2E-04 0.010 None 1.000 1 0 2019 2019
Entrez Id: 94025
Gene Symbol: MUC16
MUC16
Q8WXI7 mucin 16, cell surface associated 236 0.479 0.808 8.3E-112 0.010 None 1.000 1 0 2018 2018
Entrez Id: 4968
Gene Symbol: OGG1
OGG1
O15527 8-oxoguanine DNA glycosylase 313 0.453 0.808 3.9E-12 0.010 None 1.000 1 1 2013 2013
Entrez Id: 4953
Gene Symbol: ODC1
ODC1
P11926 ornithine decarboxylase 1 Enzyme 184 0.510 0.731 0.17 0.010 None 1.000 1 0 2001 2001
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH
Q9UIF7 mutY DNA glycosylase Enzyme 156 0.521 0.769 1.3E-18 0.010 None 1.000 1 0 2007 2007
Entrez Id: 941
Gene Symbol: CD80
CD80
P33681 CD80 molecule 233 0.475 0.769 1.1E-02 0.010 None 1.000 1 0 2018 2018