Source: CURATED ×
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7124
Gene Symbol: TNF
TNF 		P01375 tumor necrosis factor Signaling 340 0.231 0.962 0.80 0.600 None 0.950 1 0 1995 2020
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1 		P01137 transforming growth factor beta 1 Signaling 179 0.287 0.962 3.7E-02 0.700 None 1.000 1 1 2002 2020
Entrez Id: 596
Gene Symbol: BCL2
BCL2 		P10415 BCL2 apoptosis regulator Signaling 141 0.291 0.885 0.56 0.670 None 1.000 1 1 2006 2020
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		P00533 epidermal growth factor receptor Kinase 124 0.295 0.885 0.37 0.370 None 1.000 1 0 2010 2018
Entrez Id: 673
Gene Symbol: BRAF
BRAF 		P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 115 0.319 0.846 1.00 0.400 None 1.000 1 1 2017 2017
Entrez Id: 3952
Gene Symbol: LEP
LEP 		P41159 leptin 114 0.349 0.846 0.46 0.600 None 0.952 1 0 1996 2020
Entrez Id: 836
Gene Symbol: CASP3
CASP3 		P42574 caspase 3 Enzyme 72 0.351 0.923 0.10 0.390 None 1.000 1 0 2004 2020
Entrez Id: 5468
Gene Symbol: PPARG
PPARG 		P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 110 0.358 0.885 2.9E-02 0.700 None 0.953 6 10 1998 2020
Entrez Id: 847
Gene Symbol: CAT
CAT 		P04040 catalase Enzyme 171 0.359 0.962 1.6E-10 0.400 None 0.952 2 0 1992 2019
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1 		P05362 intercellular adhesion molecule 1 57 0.364 0.962 3.5E-02 0.600 None 0.862 1 0 2002 2019
Entrez Id: 4843
Gene Symbol: NOS2
NOS2 		P35228 nitric oxide synthase 2 184 0.364 0.923 4.0E-15 0.570 None 1.000 1 0 2002 2019
Entrez Id: 355
Gene Symbol: FAS
FAS 		P25445 Fas cell surface death receptor 66 0.372 0.923 0.81 0.320 None 1.000 1 0 2005 2019
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ 		Q15848 adiponectin, C1Q and collagen domain containing 66 0.376 0.885 4.6E-09 0.600 None 0.950 3 0 1999 2020
Entrez Id: 4846
Gene Symbol: NOS3
NOS3 		P29474 nitric oxide synthase 3 138 0.378 0.885 6.7E-07 0.600 None 0.900 2 0 1999 2019
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1 		Q96EB6 sirtuin 1 Epigenetic regulator 89 0.378 0.885 8.7E-02 0.600 None 1.000 1 0 2008 2020
Entrez Id: 6647
Gene Symbol: SOD1
SOD1 		P00441 superoxide dismutase 1 Enzyme 147 0.379 0.962 0.18 0.400 None 0.929 1 0 2001 2019
Entrez Id: 6648
Gene Symbol: SOD2
SOD2 		P04179 superoxide dismutase 2 Enzyme 285 0.379 0.923 0.15 0.400 None 0.941 1 0 2004 2019
Entrez Id: 1906
Gene Symbol: EDN1
EDN1 		P05305 endothelin 1 Signaling 113 0.380 0.846 0.46 0.600 None 1.000 1 0 1999 2019
Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1 		P09488 glutathione S-transferase mu 1 61 0.380 0.923 2.1E-03 0.400 None 0.950 1 0 2006 2019
Entrez Id: 7076
Gene Symbol: TIMP1
TIMP1 		P01033 TIMP metallopeptidase inhibitor 1 Enzyme modulator 28 0.380 0.885 0.50 0.350 None 0.800 1 0 2002 2018
Entrez Id: 3162
Gene Symbol: HMOX1
HMOX1 		P09601 heme oxygenase 1 137 0.381 0.923 9.7E-03 0.600 None 0.950 3 0 2002 2019
Entrez Id: 6513
Gene Symbol: SLC2A1
SLC2A1 		P11166 solute carrier family 2 member 1 Transporter 94 0.388 0.808 0.99 0.400 None 0.853 1 0 1990 2020
Entrez Id: 4790
Gene Symbol: NFKB1
NFKB1 		P19838 nuclear factor kappa B subunit 1 Transcription factor 33 0.396 0.923 1.00 0.370 None 1.000 1 0 2006 2019
Entrez Id: 841
Gene Symbol: CASP8
CASP8 		Q14790 caspase 8 Enzyme 58 0.404 0.923 3.7E-06 0.300 None 1.000 1 0 2004 2004
Entrez Id: 5970
Gene Symbol: RELA
RELA 		Q04206 RELA proto-oncogene, NF-kB subunit Transcription factor 63 0.406 0.885 1.00 0.320 None 1.000 1 0 2013 2018