Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 5167
Gene Symbol: ENPP1
ENPP1
P22413 ectonucleotide pyrophosphatase/phosphodiesterase 1 Enzyme 11 0.498 0.808 5.0E-08 0.700 moderate 0.814 0 0 2000 2019
Entrez Id: 8660
Gene Symbol: IRS2
IRS2
Q9Y4H2 insulin receptor substrate 2 18 0.535 0.654 0.99 0.700 None 0.975 0 0 1997 2017
Entrez Id: 5770
Gene Symbol: PTPN1
PTPN1
P18031 protein tyrosine phosphatase non-receptor type 1 22 0.523 0.731 0.81 0.500 None 0.961 0 0 1999 2019
Entrez Id: 10644
Gene Symbol: IGF2BP2
IGF2BP2
Q9Y6M1 insulin like growth factor 2 mRNA binding protein 2 Enzyme 3 0.588 0.615 0.24 0.500 None 0.972 0 30 2007 2019
Entrez Id: 56729
Gene Symbol: RETN
RETN
Q9HD89 resistin 16 0.454 0.808 3.7E-02 0.500 None 0.950 0 0 2001 2020
Entrez Id: 2642
Gene Symbol: GCGR
GCGR
P47871 glucagon receptor G-protein coupled receptor 2 0.656 0.308 2.2E-06 0.500 None 0.891 0 0 1995 2020
Entrez Id: 5078
Gene Symbol: PAX4
PAX4
O43316 paired box 4 10 0.644 0.423 4.2E-04 1.000 limited 0.857 1 2 1999 2019
Entrez Id: 5506
Gene Symbol: PPP1R3A
PPP1R3A
Q16821 protein phosphatase 1 regulatory subunit 3A Enzyme modulator 3 0.711 0.577 9.3E-16 1.000 limited 0.929 1 1 1994 2018
Entrez Id: 6927
Gene Symbol: HNF1A
HNF1A
P20823 HNF1 homeobox A Nucleic acid binding 28 0.478 0.846 0.96 0.900 strong 0.954 1 8 1995 2019
Entrez Id: 3159
Gene Symbol: HMGA1
HMGA1
P17096 high mobility group AT-hook 1 Nucleic acid binding 12 0.494 0.769 0.83 0.700 None 0.929 1 0 2005 2018
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
P01137 transforming growth factor beta 1 Signaling 179 0.287 0.962 3.7E-02 0.700 None 1.000 1 1 2002 2020
Entrez Id: 11132
Gene Symbol: CAPN10
CAPN10
Q9HC96 calpain 10 Enzyme 7 0.621 0.577 6.9E-13 0.700 None 0.926 1 4 2000 2019
Entrez Id: 6514
Gene Symbol: SLC2A2
SLC2A2
P11168 solute carrier family 2 member 2 Transporter 20 0.572 0.692 3.4E-08 0.700 None 0.839 1 3 1990 2019
Entrez Id: 596
Gene Symbol: BCL2
BCL2
P10415 BCL2 apoptosis regulator Signaling 141 0.291 0.885 0.56 0.670 None 1.000 1 1 2006 2020
Entrez Id: 9479
Gene Symbol: MAPK8IP1
MAPK8IP1
Q9UQF2 mitogen-activated protein kinase 8 interacting protein 1 Signaling 1 0.716 0.462 1.00 0.620 None 1.000 1 1 2000 2018
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor Signaling 340 0.231 0.962 0.80 0.600 None 0.950 1 0 1995 2020
Entrez Id: 1906
Gene Symbol: EDN1
EDN1
P05305 endothelin 1 Signaling 113 0.380 0.846 0.46 0.600 None 1.000 1 0 1999 2019
Entrez Id: 1909
Gene Symbol: EDNRA
EDNRA
P25101 endothelin receptor type A G-protein coupled receptor 28 0.426 0.885 0.99 0.600 None 1.000 1 0 2006 2018
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1
P05362 intercellular adhesion molecule 1 57 0.364 0.962 3.5E-02 0.600 None 0.862 1 0 2002 2019
Entrez Id: 3240
Gene Symbol: HP
HP
P00738 haptoglobin Enzyme 62 0.412 0.885 1.7E-05 0.600 None 0.975 1 0 1986 2019
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1
Q96EB6 sirtuin 1 Epigenetic regulator 89 0.378 0.885 8.7E-02 0.600 None 1.000 1 0 2008 2020
Entrez Id: 3952
Gene Symbol: LEP
LEP
P41159 leptin 114 0.349 0.846 0.46 0.600 None 0.952 1 0 1996 2020
Entrez Id: 7132
Gene Symbol: TNFRSF1A
TNFRSF1A
P19438 TNF receptor superfamily member 1A 41 0.409 0.923 0.99 0.590 None 1.000 1 0 2002 2019
Entrez Id: 4843
Gene Symbol: NOS2
NOS2
P35228 nitric oxide synthase 2 184 0.364 0.923 4.0E-15 0.570 None 1.000 1 0 2002 2019
Entrez Id: 9365
Gene Symbol: KL
KL
Q9UEF7 klotho Enzyme 38 0.448 0.769 2.2E-04 0.570 None 1.000 1 0 2006 2019