Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3953
Gene Symbol: LEPR
LEPR
P48357 leptin receptor Signaling 79 0.433 0.808 0.99 0.600 None 0.975 4 0 1966 2019
Entrez Id: 3630
Gene Symbol: INS
INS
P01308 insulin 157 0.445 0.923 0.30 0.700 None 0.978 10 1 1983 2020
Entrez Id: 3643
Gene Symbol: INSR
INSR
P06213 insulin receptor Kinase 60 0.432 0.846 3.6E-05 0.700 None 0.962 3 2 1985 2020
Entrez Id: 3240
Gene Symbol: HP
HP
P00738 haptoglobin Enzyme 62 0.412 0.885 1.7E-05 0.600 None 0.975 1 0 1986 2019
Entrez Id: 2641
Gene Symbol: GCG
GCG
P01275 glucagon 43 0.431 0.885 3.5E-02 0.400 None 0.990 1 0 1986 2020
Entrez Id: 3375
Gene Symbol: IAPP
IAPP
P10997 islet amyloid polypeptide Signaling 5 0.507 0.808 3.2E-03 0.400 None 0.958 2 0 1989 2020
Entrez Id: 6517
Gene Symbol: SLC2A4
SLC2A4
P14672 solute carrier family 2 member 4 Transporter 15 0.528 0.769 4.7E-05 0.800 None 0.951 6 1 1990 2020
Entrez Id: 6513
Gene Symbol: SLC2A1
SLC2A1
P11166 solute carrier family 2 member 1 Transporter 94 0.388 0.808 0.99 0.400 None 0.853 1 0 1990 2020
Entrez Id: 6514
Gene Symbol: SLC2A2
SLC2A2
P11168 solute carrier family 2 member 2 Transporter 20 0.572 0.692 3.4E-08 0.700 None 0.839 1 3 1990 2019
Entrez Id: 3039
Gene Symbol: HBA1
HBA1
P69905 hemoglobin subunit alpha 1 33 0.508 0.808 6.7E-03 0.360 None 0.714 1 0 1991 2017
Entrez Id: 3172
Gene Symbol: HNF4A
HNF4A
P41235 hepatocyte nuclear factor 4 alpha Nuclear receptor 8 0.461 0.808 0.15 1.000 None 0.942 5 8 1992 2019
Entrez Id: 2645
Gene Symbol: GCK
GCK
P35557 glucokinase Kinase 17 0.523 0.808 0.63 0.900 strong 0.953 4 7 1992 2020
Entrez Id: 847
Gene Symbol: CAT
CAT
P04040 catalase Enzyme 171 0.359 0.962 1.6E-10 0.400 None 0.952 2 0 1992 2019
Entrez Id: 3667
Gene Symbol: IRS1
IRS1
P35568 insulin receptor substrate 1 24 0.488 0.769 2.4E-02 0.900 None 0.939 9 2 1993 2019
Entrez Id: 2740
Gene Symbol: GLP1R
GLP1R
P43220 glucagon like peptide 1 receptor G-protein coupled receptor 6 0.471 0.846 0.29 0.500 None 0.978 1 1 1993 2020
Entrez Id: 3098
Gene Symbol: HK1
HK1
P19367 hexokinase 1 Kinase 18 0.542 0.731 0.91 0.320 None 1.000 1 0 1993 2011
Entrez Id: 5506
Gene Symbol: PPP1R3A
PPP1R3A
Q16821 protein phosphatase 1 regulatory subunit 3A Enzyme modulator 3 0.711 0.577 9.3E-16 1.000 limited 0.929 1 1 1994 2018
Entrez Id: 6833
Gene Symbol: ABCC8
ABCC8
Q09428 ATP binding cassette subfamily C member 8 Transporter 20 0.474 0.846 8.0E-24 0.700 None 0.900 2 8 1995 2018
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor Signaling 340 0.231 0.962 0.80 0.600 None 0.950 1 0 1995 2020
Entrez Id: 6927
Gene Symbol: HNF1A
HNF1A
P20823 HNF1 homeobox A Nucleic acid binding 28 0.478 0.846 0.96 0.900 strong 0.954 1 8 1995 2019
Entrez Id: 5126
Gene Symbol: PCSK2
PCSK2
P16519 proprotein convertase subtilisin/kexin type 2 Enzyme 5 0.663 0.462 1.00 0.360 None 1.000 1 0 1995 2017
Entrez Id: 2642
Gene Symbol: GCGR
GCGR
P47871 glucagon receptor G-protein coupled receptor 2 0.656 0.308 2.2E-06 0.500 None 0.891 0 0 1995 2020
Entrez Id: 3767
Gene Symbol: KCNJ11
KCNJ11
Q14654 potassium inwardly rectifying channel subfamily J member 11 Ion channel 50 0.529 0.615 1.1E-02 0.900 strong 0.943 2 5 1996 2019
Entrez Id: 2820
Gene Symbol: GPD2
GPD2
P43304 glycerol-3-phosphate dehydrogenase 2 Enzyme 10 0.678 0.538 8.1E-11 0.450 None 0.833 1 1 1996 2005
Entrez Id: 3952
Gene Symbol: LEP
LEP
P41159 leptin 114 0.349 0.846 0.46 0.600 None 0.952 1 0 1996 2020