Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 5167
Gene Symbol: ENPP1
ENPP1
P22413 ectonucleotide pyrophosphatase/phosphodiesterase 1 Enzyme 11 0.498 0.808 5.0E-08 0.700 moderate 0.814 0 0 2000 2019
Entrez Id: 3990
Gene Symbol: LIPC
LIPC
P11150 lipase C, hepatic type Enzyme 17 0.585 0.654 3.3E-07 0.680 None 1.000 3 1 2001 2018
Entrez Id: 596
Gene Symbol: BCL2
BCL2
P10415 BCL2 apoptosis regulator Signaling 141 0.291 0.885 0.56 0.670 None 1.000 1 1 2006 2020
Entrez Id: 9479
Gene Symbol: MAPK8IP1
MAPK8IP1
Q9UQF2 mitogen-activated protein kinase 8 interacting protein 1 Signaling 1 0.716 0.462 1.00 0.620 None 1.000 1 1 2000 2018
Entrez Id: 3953
Gene Symbol: LEPR
LEPR
P48357 leptin receptor Signaling 79 0.433 0.808 0.99 0.600 None 0.975 4 0 1966 2019
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
Q15848 adiponectin, C1Q and collagen domain containing 66 0.376 0.885 4.6E-09 0.600 None 0.950 3 0 1999 2020
Entrez Id: 3162
Gene Symbol: HMOX1
HMOX1
P09601 heme oxygenase 1 137 0.381 0.923 9.7E-03 0.600 None 0.950 3 0 2002 2019
Entrez Id: 10891
Gene Symbol: PPARGC1A
PPARGC1A
Q9UBK2 PPARG coactivator 1 alpha Transcription factor 18 0.453 0.885 1.00 0.600 None 0.925 2 0 2001 2020
Entrez Id: 7351
Gene Symbol: UCP2
UCP2
P55851 uncoupling protein 2 Transporter 28 0.493 0.808 1.5E-10 0.600 None 0.857 2 0 1998 2019
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
P29474 nitric oxide synthase 3 138 0.378 0.885 6.7E-07 0.600 None 0.900 2 0 1999 2019
Entrez Id: 1906
Gene Symbol: EDN1
EDN1
P05305 endothelin 1 Signaling 113 0.380 0.846 0.46 0.600 None 1.000 1 0 1999 2019
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1
Q96EB6 sirtuin 1 Epigenetic regulator 89 0.378 0.885 8.7E-02 0.600 None 1.000 1 0 2008 2020
Entrez Id: 1909
Gene Symbol: EDNRA
EDNRA
P25101 endothelin receptor type A G-protein coupled receptor 28 0.426 0.885 0.99 0.600 None 1.000 1 0 2006 2018
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1
P05362 intercellular adhesion molecule 1 57 0.364 0.962 3.5E-02 0.600 None 0.862 1 0 2002 2019
Entrez Id: 3952
Gene Symbol: LEP
LEP
P41159 leptin 114 0.349 0.846 0.46 0.600 None 0.952 1 0 1996 2020
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor Signaling 340 0.231 0.962 0.80 0.600 None 0.950 1 0 1995 2020
Entrez Id: 3240
Gene Symbol: HP
HP
P00738 haptoglobin Enzyme 62 0.412 0.885 1.7E-05 0.600 None 0.975 1 0 1986 2019
Entrez Id: 7132
Gene Symbol: TNFRSF1A
TNFRSF1A
P19438 TNF receptor superfamily member 1A 41 0.409 0.923 0.99 0.590 None 1.000 1 0 2002 2019
Entrez Id: 4843
Gene Symbol: NOS2
NOS2
P35228 nitric oxide synthase 2 184 0.364 0.923 4.0E-15 0.570 None 1.000 1 0 2002 2019
Entrez Id: 9365
Gene Symbol: KL
KL
Q9UEF7 klotho Enzyme 38 0.448 0.769 2.2E-04 0.570 None 1.000 1 0 2006 2019
Entrez Id: 1374
Gene Symbol: CPT1A
CPT1A
P50416 carnitine palmitoyltransferase 1A Enzyme 14 0.555 0.808 5.1E-09 0.560 None 1.000 1 0 2005 2019
Entrez Id: 6616
Gene Symbol: SNAP25
SNAP25
P60880 synaptosome associated protein 25 Transporter 36 0.489 0.808 0.99 0.520 None 1.000 1 0 2005 2017
Entrez Id: 1910
Gene Symbol: EDNRB
EDNRB
P24530 endothelin receptor type B G-protein coupled receptor 31 0.470 0.846 9.2E-03 0.510 None 1.000 1 0 2006 2009
Entrez Id: 488
Gene Symbol: ATP2A2
ATP2A2
P16615 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 Transporter 34 0.529 0.808 1.00 0.510 None 1.000 1 0 2005 2016
Entrez Id: 169026
Gene Symbol: SLC30A8
SLC30A8
Q8IWU4 solute carrier family 30 member 8 Transporter 1 0.623 0.731 7.4E-12 0.500 None 0.963 6 6 2007 2019