Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.230 None 1.000 8 0 1995 2018
Entrez Id: 7450
Gene Symbol: VWF
VWF
P04275 von Willebrand factor Enzyme modulator 498 0.408 0.885 3.2E-25 0.070 None 1.000 7 0 2018 2020
Entrez Id: 5972
Gene Symbol: REN
REN
P00797 renin Enzyme 721 0.370 0.923 2.4E-07 0.060 None 1.000 6 0 2005 2019
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
P15692 vascular endothelial growth factor A Signaling 1899 0.266 0.923 2.4E-05 0.540 None 1.000 5 0 2008 2016
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
P29474 nitric oxide synthase 3 706 0.378 0.885 6.7E-07 0.510 None 1.000 5 0 2000 2017
Entrez Id: 1636
Gene Symbol: ACE
ACE
P12821 angiotensin I converting enzyme Enzyme 1082 0.328 0.923 1.0E-37 0.050 None 1.000 5 2 2003 2019
Entrez Id: 3162
Gene Symbol: HMOX1
HMOX1
P09601 heme oxygenase 1 666 0.381 0.923 9.7E-03 0.230 None 1.000 4 0 2003 2017
Entrez Id: 1716
Gene Symbol: DGUOK
DGUOK
Q16854 deoxyguanosine kinase Kinase 112 0.593 0.500 3.7E-07 0.430 None 1.000 3 0 2016 2019
Entrez Id: 213
Gene Symbol: ALB
ALB
P02768 albumin Transporter 1198 0.317 0.962 0.64 0.030 None 1.000 3 0 2017 2018
Entrez Id: 4142
Gene Symbol: MAS1
MAS1
P04201 MAS1 proto-oncogene, G protein-coupled receptor G-protein coupled receptor 142 0.533 0.769 8.3E-05 0.030 None 1.000 3 0 2018 2019
Entrez Id: 151306
Gene Symbol: GPBAR1
GPBAR1
Q8TDU6 G protein-coupled bile acid receptor 1 G-protein coupled receptor 122 0.548 0.731 1.4E-09 0.030 None 1.000 3 0 2017 2017
Entrez Id: 9971
Gene Symbol: NR1H4
NR1H4
Q96RI1 nuclear receptor subfamily 1 group H member 4 Nuclear receptor 187 0.513 0.808 9.4E-04 0.220 None 1.000 3 0 2009 2017
Entrez Id: 5265
Gene Symbol: SERPINA1
SERPINA1
P01009 serpin family A member 1 Enzyme modulator 482 0.410 0.923 6.8E-08 0.020 None 1.000 2 2 2010 2019
Entrez Id: 285
Gene Symbol: ANGPT2
ANGPT2
O15123 angiopoietin 2 Signaling 457 0.410 0.846 0.83 0.210 None 1.000 2 0 2009 2012
Entrez Id: 551
Gene Symbol: AVP
AVP
P01185 arginine vasopressin Signaling 454 0.437 0.846 7.4E-02 0.500 None 1.000 2 0 1984 2009
Entrez Id: 4851
Gene Symbol: NOTCH1
NOTCH1
P46531 notch receptor 1 693 0.369 0.885 1.00 0.120 None 1.000 2 0 2012 2014
Entrez Id: 5919
Gene Symbol: RARRES2
RARRES2
Q99969 retinoic acid receptor responder 2 180 0.519 0.731 2.7E-05 0.020 None 1.000 2 0 2015 2018
Entrez Id: 59272
Gene Symbol: ACE2
ACE2
Q9BYF1 angiotensin I converting enzyme 2 Enzyme 253 0.477 0.769 1.00 0.020 None 1.000 2 0 2018 2019
Entrez Id: 5295
Gene Symbol: PIK3R1
PIK3R1
P27986 phosphoinositide-3-kinase regulatory subunit 1 Kinase 285 0.477 0.885 1.00 0.210 None 1.000 2 0 2002 2010
Entrez Id: 4842
Gene Symbol: NOS1
NOS1
P29475 nitric oxide synthase 1 521 0.408 0.885 1.00 0.210 None 1.000 2 0 2000 2004
Entrez Id: 23576
Gene Symbol: DDAH1
DDAH1
O94760 dimethylarginine dimethylaminohydrolase 1 Enzyme 73 0.604 0.615 2.8E-03 0.020 None 1.000 2 0 2015 2017
Entrez Id: 1906
Gene Symbol: EDN1
EDN1
P05305 endothelin 1 Signaling 679 0.380 0.846 0.46 0.210 None 1.000 2 0 2000 2007
Entrez Id: 80315
Gene Symbol: CPEB4
CPEB4
Q17RY0 cytoplasmic polyadenylation element binding protein 4 Nucleic acid binding 70 0.621 0.462 0.99 0.020 None 1.000 2 0 2016 2017
Entrez Id: 3717
Gene Symbol: JAK2
JAK2
O60674 Janus kinase 2 Kinase 644 0.385 0.885 0.65 0.120 None 1.000 2 0 2017 2019
Entrez Id: 8654
Gene Symbol: PDE5A
PDE5A
O76074 phosphodiesterase 5A 187 0.513 0.731 1.1E-04 0.020 None 1.000 2 0 2018 2018