Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 26191
Gene Symbol: PTPN22
PTPN22
Q9Y2R2 protein tyrosine phosphatase non-receptor type 22 400 0.438 0.846 3.5E-21 0.400 None 0.714 14 1 2005 2019
Entrez Id: 3378
Gene Symbol: IBD2
IBD2
inflammatory bowel disease 2 13 0.805 0.154 0.100 None 1.000 14 0 1998 2012
Entrez Id: 4650
Gene Symbol: MYO9B
MYO9B
Q13459 myosin IXB 65 0.644 0.615 1.00 0.100 None 0.857 14 5 2006 2016
Entrez Id: 3106
Gene Symbol: HLA-B
HLA-B
P01889 major histocompatibility complex, class I, B 706 0.379 0.885 3.9E-05 0.200 None 1.000 12 1 2000 2020
Entrez Id: 3578
Gene Symbol: IL9
IL9
P15248 interleukin 9 291 0.461 0.846 8.1E-07 0.100 None 1.000 12 0 2001 2019
Entrez Id: 59067
Gene Symbol: IL21
IL21
Q9HBE4 interleukin 21 321 0.441 0.769 0.63 0.100 None 1.000 12 0 2008 2020
Entrez Id: 929
Gene Symbol: CD14
CD14
P08571 CD14 molecule 551 0.392 0.885 4.9E-05 0.100 None 1.000 12 0 2005 2018
Entrez Id: 1493
Gene Symbol: CTLA4
CTLA4
P16410 cytotoxic T-lymphocyte associated protein 4 722 0.369 0.923 0.94 0.100 None 0.727 11 1 2002 2018
Entrez Id: 54210
Gene Symbol: TREM1
TREM1
Q9NP99 triggering receptor expressed on myeloid cells 1 172 0.515 0.808 6.3E-03 0.100 None 1.000 11 1 2006 2019
Entrez Id: 7097
Gene Symbol: TLR2
TLR2
O60603 toll like receptor 2 749 0.361 0.923 1.0E-06 0.100 None 0.909 11 7 2007 2018
Entrez Id: 4210
Gene Symbol: MEFV
MEFV
O15553 MEFV innate immuity regulator, pyrin 410 0.440 0.885 1.0E-14 0.100 None 0.900 10 1 2008 2019
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
P42898 methylenetetrahydrofolate reductase 985 0.337 0.885 3.2E-10 0.100 None 0.900 10 2 1999 2016
Entrez Id: 55270
Gene Symbol: NUDT15
NUDT15
Q9NV35 nudix hydrolase 15 33 0.670 0.538 1.7E-03 0.190 None 1.000 10 2 2016 2019
Entrez Id: 246778
Gene Symbol: IL27
IL27
Q8NEV9 interleukin 27 286 0.457 0.808 0.78 0.170 None 1.000 9 2 2009 2017
Entrez Id: 30829
Gene Symbol: IBD3
IBD3
inflammatory bowel disease 3 5 0.861 0.038 0.090 None 0.889 9 0 2000 2018
Entrez Id: 406947
Gene Symbol: MIR155
MIR155
microRNA 155 584 0.384 0.885 0.090 None 1.000 9 0 2013 2019
Entrez Id: 54106
Gene Symbol: TLR9
TLR9
Q9NR96 toll like receptor 9 457 0.411 0.885 9.8E-06 0.090 None 1.000 9 3 2009 2019
Entrez Id: 6863
Gene Symbol: TAC1
TAC1
P20366 tachykinin precursor 1 478 0.424 0.923 0.75 0.090 None 1.000 9 0 1996 2019
Entrez Id: 27035
Gene Symbol: NOX1
NOX1
Q9Y5S8 NADPH oxidase 1 142 0.536 0.808 8.7E-08 0.080 None 1.000 8 1 2015 2019
Entrez Id: 324
Gene Symbol: APC
APC
P25054 APC regulator of WNT signaling pathway 703 0.373 0.962 1.00 0.370 None 0.875 8 2 1997 2016
Entrez Id: 3596
Gene Symbol: IL13
IL13
P35225 interleukin 13 587 0.386 0.846 1.4E-02 0.080 None 1.000 8 0 2008 2019
Entrez Id: 3600
Gene Symbol: IL15
IL15
P40933 interleukin 15 426 0.422 0.846 0.71 0.080 None 1.000 8 0 1998 2019
Entrez Id: 406991
Gene Symbol: MIR21
MIR21
microRNA 21 726 0.363 0.846 0.080 None 1.000 8 0 2013 2018
Entrez Id: 57817
Gene Symbol: HAMP
HAMP
P81172 hepcidin antimicrobial peptide 377 0.433 0.846 8.2E-03 0.080 None 1.000 8 0 2012 2020
Entrez Id: 100507436
Gene Symbol: MICA
MICA
Q29983 MHC class I polypeptide-related sequence A 248 0.473 0.846 5.0E-03 0.070 None 1.000 7 1 2001 2013