Source: CLINVAR ×
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 2322
Gene Symbol: FLT3
FLT3 		P36888 fms related receptor tyrosine kinase 3 Kinase 2 0.462 0.654 0.61 1.000 None 0.985 34 28 1992 2020
Entrez Id: 1050
Gene Symbol: CEBPA
CEBPA 		P49715 CCAAT enhancer binding protein alpha Transcription factor 1 0.496 0.692 0.55 1.000 definitive 0.985 0 14 1992 2020
Entrez Id: 3717
Gene Symbol: JAK2
JAK2 		O60674 Janus kinase 2 Kinase 12 0.385 0.885 0.65 0.800 None 0.945 11 2 2005 2019
Entrez Id: 1788
Gene Symbol: DNMT3A
DNMT3A 		Q9Y6K1 DNA methyltransferase 3 alpha 14 0.445 0.846 7.4E-39 0.800 limited 0.955 10 4 2009 2019
Entrez Id: 861
Gene Symbol: RUNX1
RUNX1 		Q01196 RUNX family transcription factor 1 Transcription factor 7 0.425 0.808 0.65 0.800 strong 0.985 5 3 1991 2020
Entrez Id: 3815
Gene Symbol: KIT
KIT 		P10721 KIT proto-oncogene, receptor tyrosine kinase Kinase 21 0.366 0.808 0.98 0.800 moderate 0.955 3 3 1989 2019
Entrez Id: 2624
Gene Symbol: GATA2
GATA2 		P23769 GATA binding protein 2 5 0.496 0.654 0.98 0.800 None 0.974 2 2 1994 2020
Entrez Id: 5781
Gene Symbol: PTPN11
PTPN11 		Q06124 protein tyrosine phosphatase non-receptor type 11 153 0.385 0.923 1.00 0.800 None 1.000 1 2 2003 2019
Entrez Id: 2120
Gene Symbol: ETV6
ETV6 		P41212 ETS variant transcription factor 6 Transcription factor 6 0.477 0.731 0.97 0.800 strong 0.981 0 2 1995 2019
Entrez Id: 3418
Gene Symbol: IDH2
IDH2 		P48735 isocitrate dehydrogenase (NADP(+)) 2 9 0.434 0.808 0.88 0.700 None 0.961 14 5 2010 2019
Entrez Id: 4893
Gene Symbol: NRAS
NRAS 		P01111 NRAS proto-oncogene, GTPase Enzyme modulator 37 0.390 0.808 0.49 0.700 None 0.987 9 6 1984 2019
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		P01116 KRAS proto-oncogene, GTPase Enzyme modulator 66 0.320 0.923 7.9E-04 0.700 None 0.939 9 7 1987 2020
Entrez Id: 3417
Gene Symbol: IDH1
IDH1 		O75874 isocitrate dehydrogenase (NADP(+)) 1 18 0.424 0.808 2.6E-12 0.700 None 0.969 8 2 2009 2020
Entrez Id: 7490
Gene Symbol: WT1
WT1 		P19544 WT1 transcription factor Nucleic acid binding 20 0.422 0.808 1.00 0.700 None 0.959 6 1 1994 2020
Entrez Id: 7157
Gene Symbol: TP53
TP53 		P04637 tumor protein p53 Transcription factor 84 0.236 0.962 0.53 0.700 None 0.961 6 27 1986 2020
Entrez Id: 4869
Gene Symbol: NPM1
NPM1 		P06748 nucleophosmin 1 Chaperone 1 0.464 0.846 1.00 0.700 None 0.983 1 5 1996 2020
Entrez Id: 64324
Gene Symbol: NSD1
NSD1 		Q96L73 nuclear receptor binding SET domain protein 1 Epigenetic regulator 54 0.505 0.769 1.00 0.700 strong 1.000 0 4 2002 2019
Entrez Id: 23451
Gene Symbol: SF3B1
SF3B1 		O75533 splicing factor 3b subunit 1 Nucleic acid binding 8 0.511 0.731 1.00 0.500 None 1.000 2 6 2000 2020
Entrez Id: 3265
Gene Symbol: HRAS
HRAS 		P01112 HRas proto-oncogene, GTPase Enzyme modulator 71 0.378 0.885 8.0E-02 0.500 None 0.833 1 8 1987 2016
Entrez Id: 1441
Gene Symbol: CSF3R
CSF3R 		Q99062 colony stimulating factor 3 receptor Signaling 5 0.550 0.692 1.5E-10 0.500 None 0.980 1 1 1995 2019
Entrez Id: 7307
Gene Symbol: U2AF1
U2AF1 		P0DN76 Q01081 U2 small nuclear RNA auxiliary factor 1 Nucleic acid binding 9 0.604 0.577 0.99 0.470 None 1.000 4 2 2011 2019
Entrez Id: 3716
Gene Symbol: JAK1
JAK1 		P23458 Janus kinase 1 Kinase 5 0.474 0.769 1.00 0.430 None 1.000 2 1 2008 2018
Entrez Id: 51428
Gene Symbol: DDX41
DDX41 		Q9UJV9 DEAD-box helicase 41 2 0.636 0.538 5.6E-08 0.190 None 1.000 0 1 2015 2019
Entrez Id: 7010
Gene Symbol: TEK
TEK 		Q02763 TEK receptor tyrosine kinase Kinase 3 0.462 0.692 1.00 0.140 None 1.000 1 1 2002 2009
Entrez Id: 343641
Gene Symbol: TGM6
TGM6 		O95932 transglutaminase 6 2 0.644 0.423 1.1E-24 0.110 None 1.000 0 1 2015 2015