Source: CURATED ×
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7124
Gene Symbol: TNF
TNF 		P01375 tumor necrosis factor Signaling 340 0.231 0.962 0.80 0.400 None 0.912 2 0 1992 2019
Entrez Id: 7157
Gene Symbol: TP53
TP53 		P04637 tumor protein p53 Transcription factor 232 0.236 0.962 0.53 0.400 None 0.975 2 0 1991 2020
Entrez Id: 3569
Gene Symbol: IL6
IL6 		P05231 interleukin 6 270 0.248 0.962 0.32 0.400 None 0.941 1 0 1996 2019
Entrez Id: 3553
Gene Symbol: IL1B
IL1B 		P01584 interleukin 1 beta 231 0.276 0.962 0.13 0.500 None 0.907 3 0 2000 2018
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA 		P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 98 0.292 0.923 1.00 0.700 None 0.992 1 0 2005 2020
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		P00533 epidermal growth factor receptor Kinase 124 0.295 0.885 0.37 0.400 None 0.989 3 0 1986 2019
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A 		P42771 Q8N726 cyclin dependent kinase inhibitor 2A 115 0.300 0.885 0.39 0.400 None 0.947 1 0 1996 2017
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8 		P10145 C-X-C motif chemokine ligand 8 Signaling 109 0.310 0.962 2.7E-04 0.400 None 0.950 2 0 1992 2019
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2 		P35354 prostaglandin-endoperoxide synthase 2 Enzyme 239 0.314 0.962 1.00 0.400 None 0.979 4 0 1998 2020
Entrez Id: 213
Gene Symbol: ALB
ALB 		P02768 albumin Transporter 123 0.317 0.962 0.64 0.400 None 1.000 1 0 2003 2019
Entrez Id: 673
Gene Symbol: BRAF
BRAF 		P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 115 0.319 0.846 1.00 0.380 None 1.000 0 0 2003 2018
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		P01116 KRAS proto-oncogene, GTPase Enzyme modulator 164 0.320 0.923 7.9E-04 0.500 None 1.000 2 0 1987 2019
Entrez Id: 6774
Gene Symbol: STAT3
STAT3 		P40763 signal transducer and activator of transcription 3 Nucleic acid binding 138 0.320 0.923 1.00 0.400 None 1.000 1 0 2005 2019
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		P04626 erb-b2 receptor tyrosine kinase 2 Kinase 83 0.328 0.923 6.0E-03 0.700 None 0.963 3 0 1988 2020
Entrez Id: 1636
Gene Symbol: ACE
ACE 		P12821 angiotensin I converting enzyme Enzyme 101 0.328 0.923 1.0E-37 0.370 None 1.000 1 0 2005 2015
Entrez Id: 5594
Gene Symbol: MAPK1
MAPK1 		P28482 mitogen-activated protein kinase 1 Kinase 69 0.330 0.923 1.00 0.400 None 1.000 1 0 1994 2019
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR 		P42898 methylenetetrahydrofolate reductase 192 0.337 0.885 3.2E-10 0.400 None 0.951 2 0 2001 2019
Entrez Id: 4609
Gene Symbol: MYC
MYC 		P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 91 0.344 0.923 1.00 0.400 None 1.000 2 0 1995 2019
Entrez Id: 595
Gene Symbol: CCND1
CCND1 		P24385 cyclin D1 Enzyme modulator 96 0.344 0.923 0.89 0.400 None 0.926 1 0 2001 2019
Entrez Id: 627
Gene Symbol: BDNF
BDNF 		P23560 brain derived neurotrophic factor Signaling 119 0.345 0.923 0.66 0.320 None 1.000 1 0 2006 2019
Entrez Id: 5468
Gene Symbol: PPARG
PPARG 		P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 110 0.358 0.885 2.9E-02 0.400 None 1.000 2 0 2000 2016
Entrez Id: 5054
Gene Symbol: SERPINE1
SERPINE1 		P05121 serpin family E member 1 Enzyme modulator 44 0.359 0.885 4.4E-02 0.400 None 1.000 1 0 1996 2019
Entrez Id: 960
Gene Symbol: CD44
CD44 		P16070 CD44 molecule (Indian blood group) 31 0.363 0.962 2.4E-07 0.400 None 0.982 1 0 1993 2019
Entrez Id: 324
Gene Symbol: APC
APC 		P25054 APC regulator of WNT signaling pathway 95 0.373 0.962 1.00 0.700 None 0.950 0 0 1992 2019
Entrez Id: 3557
Gene Symbol: IL1RN
IL1RN 		P18510 interleukin 1 receptor antagonist 92 0.373 0.923 3.1E-02 0.500 None 0.833 0 0 2003 2018