Source: CURATED ×
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 324
Gene Symbol: APC
APC 		P25054 APC regulator of WNT signaling pathway 95 0.373 0.962 1.00 0.700 None 0.950 0 0 1992 2019
Entrez Id: 1316
Gene Symbol: KLF6
KLF6 		Q99612 Kruppel like factor 6 Nucleic acid binding 12 0.501 0.846 0.98 0.660 None 1.000 0 0 2005 2019
Entrez Id: 3659
Gene Symbol: IRF1
IRF1 		P10914 interferon regulatory factor 1 Transcription factor 14 0.468 0.769 0.99 0.660 None 1.000 0 0 1998 2019
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		Q9UIF7 mutY DNA glycosylase Enzyme 19 0.521 0.769 1.3E-18 0.640 None 1.000 0 0 2004 2011
Entrez Id: 843
Gene Symbol: CASP10
CASP10 		Q92851 caspase 10 Enzyme 23 0.528 0.692 4.6E-12 0.610 None 1.000 0 0 2002 2002
Entrez Id: 3557
Gene Symbol: IL1RN
IL1RN 		P18510 interleukin 1 receptor antagonist 92 0.373 0.923 3.1E-02 0.500 None 0.833 0 0 2003 2018
Entrez Id: 4436
Gene Symbol: MSH2
MSH2 		P43246 mutS homolog 2 Nucleic acid binding 24 0.406 0.808 0.90 0.400 None 1.000 0 5 1998 2020
Entrez Id: 2065
Gene Symbol: ERBB3
ERBB3 		P21860 erb-b2 receptor tyrosine kinase 3 Kinase 42 0.448 0.808 1.7E-15 0.400 None 1.000 0 0 2003 2019
Entrez Id: 4292
Gene Symbol: MLH1
MLH1 		P40692 mutL homolog 1 Nucleic acid binding 31 0.399 0.808 3.4E-05 0.400 None 0.980 0 3 1996 2020
Entrez Id: 673
Gene Symbol: BRAF
BRAF 		P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 115 0.319 0.846 1.00 0.380 None 1.000 0 0 2003 2018
Entrez Id: 51366
Gene Symbol: UBR5
UBR5 		O95071 ubiquitin protein ligase E3 component n-recognin 5 8 0.597 0.654 1.00 0.320 None 1.000 0 0 2006 2016
Entrez Id: 545
Gene Symbol: ATR
ATR 		Q13535 ATR serine/threonine kinase Kinase 30 0.456 0.923 3.5E-09 0.320 None 1.000 0 0 1999 2005
Entrez Id: 8313
Gene Symbol: AXIN2
AXIN2 		Q9Y2T1 axin 2 20 0.507 0.692 0.57 0.310 None 1.000 0 0 2009 2009
Entrez Id: 5426
Gene Symbol: POLE
POLE 		Q07864 DNA polymerase epsilon, catalytic subunit 17 0.526 0.731 8.0E-27 0.310 None 1.000 0 0 2013 2013
Entrez Id: 11122
Gene Symbol: PTPRT
PTPRT 		O14522 protein tyrosine phosphatase receptor type T Enzyme 4 0.636 0.538 1.00 0.300 None 0 1
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA 		P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 98 0.292 0.923 1.00 0.700 None 0.992 1 0 2005 2020
Entrez Id: 472
Gene Symbol: ATM
ATM 		Q13315 ATM serine/threonine kinase Kinase 72 0.374 0.885 5.6E-47 0.600 None 1.000 1 0 1998 2019
Entrez Id: 5562
Gene Symbol: PRKAA1
PRKAA1 		Q13131 protein kinase AMP-activated catalytic subunit alpha 1 Kinase 10 0.453 0.846 0.14 0.500 None 0.944 1 1 2011 2019
Entrez Id: 11200
Gene Symbol: CHEK2
CHEK2 		O96017 checkpoint kinase 2 Kinase 47 0.460 0.808 1.2E-24 0.460 None 0.857 1 0 2000 2018
Entrez Id: 26137
Gene Symbol: ZBTB20
ZBTB20 		Q9HC78 zinc finger and BTB domain containing 20 8 0.566 0.731 0.97 0.430 None 1.000 1 1 2011 2019
Entrez Id: 7517
Gene Symbol: XRCC3
XRCC3 		O43542 X-ray repair cross complementing 3 27 0.505 0.769 1.9E-10 0.400 None 0.636 1 0 2004 2017
Entrez Id: 857
Gene Symbol: CAV1
CAV1 		Q03135 caveolin 1 Enzyme modulator 58 0.388 0.885 8.3E-03 0.400 None 1.000 1 0 2006 2017
Entrez Id: 2272
Gene Symbol: FHIT
FHIT 		P49789 fragile histidine triad diadenosine triphosphatase 32 0.444 0.846 5.7E-03 0.400 None 1.000 1 0 1997 2014
Entrez Id: 174
Gene Symbol: AFP
AFP 		P02771 alpha fetoprotein Transporter 19 0.429 0.885 1.1E-11 0.400 None 1.000 1 0 2001 2019
Entrez Id: 1026
Gene Symbol: CDKN1A
CDKN1A 		P38936 cyclin dependent kinase inhibitor 1A 34 0.403 0.769 1.9E-03 0.400 None 0.917 1 0 2001 2019