Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
P60484 phosphatase and tensin homolog Enzyme 1349 0.305 0.923 0.26 0.090 None 1.000 9 0 2004 2018
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
P04626 erb-b2 receptor tyrosine kinase 2 Kinase 995 0.328 0.923 6.0E-03 0.370 None 1.000 8 0 2001 2018
Entrez Id: 10413
Gene Symbol: YAP1
YAP1
P46937 Yes associated protein 1 Enzyme modulator 374 0.432 0.808 1.00 0.080 None 1.000 8 0 2016 2019
Entrez Id: 841
Gene Symbol: CASP8
CASP8
Q14790 caspase 8 Enzyme 480 0.404 0.923 3.7E-06 0.080 None 1.000 8 0 2004 2009
Entrez Id: 1654
Gene Symbol: DDX3X
DDX3X
O00571 DEAD-box helicase 3 X-linked 180 0.537 0.769 1.00 0.080 None 1.000 8 0 2012 2019
Entrez Id: 11186
Gene Symbol: RASSF1
RASSF1
Q9NS23 Ras association domain family member 1 Enzyme modulator 400 0.420 0.808 4.9E-06 0.370 None 1.000 7 0 2002 2011
Entrez Id: 10763
Gene Symbol: NES
NES
P48681 nestin 302 0.450 0.808 1.6E-06 0.070 None 1.000 7 0 2004 2019
Entrez Id: 4851
Gene Symbol: NOTCH1
NOTCH1
P46531 notch receptor 1 693 0.369 0.885 1.00 0.070 None 1.000 7 0 2009 2019
Entrez Id: 7852
Gene Symbol: CXCR4
CXCR4
P61073 C-X-C motif chemokine receptor 4 G-protein coupled receptor 739 0.362 0.923 1.8E-02 0.070 None 1.000 7 1 2005 2018
Entrez Id: 5156
Gene Symbol: PDGFRA
PDGFRA
P16234 platelet derived growth factor receptor alpha Kinase 452 0.415 0.808 1.00 0.360 None 1.000 7 0 2001 2015
Entrez Id: 4804
Gene Symbol: NGFR
NGFR
P08138 nerve growth factor receptor Receptor 256 0.477 0.846 9.8E-02 0.070 None 1.000 7 0 1990 2018
Entrez Id: 595
Gene Symbol: CCND1
CCND1
P24385 cyclin D1 Enzyme modulator 859 0.344 0.923 0.89 0.070 None 1.000 7 0 2005 2017
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
P00533 epidermal growth factor receptor Kinase 1394 0.295 0.885 0.37 0.070 None 1.000 7 0 2003 2018
Entrez Id: 5347
Gene Symbol: PLK1
PLK1
P53350 polo like kinase 1 Kinase 253 0.467 0.808 0.98 0.070 None 1.000 7 0 2011 2019
Entrez Id: 3082
Gene Symbol: HGF
HGF
P14210 hepatocyte growth factor Enzyme 671 0.374 0.885 1.00 0.070 None 0.857 7 0 2005 2012
Entrez Id: 4233
Gene Symbol: MET
MET
P08581 MET proto-oncogene, receptor tyrosine kinase Kinase 594 0.380 0.846 0.97 0.060 None 1.000 6 0 2008 2015
Entrez Id: 8493
Gene Symbol: PPM1D
PPM1D
O15297 protein phosphatase, Mg2+/Mn2+ dependent 1D Enzyme 177 0.513 0.808 2.2E-11 0.060 None 1.000 6 0 2005 2016
Entrez Id: 6657
Gene Symbol: SOX2
SOX2
P48431 SRY-box transcription factor 2 Transcription factor 503 0.405 0.808 0.71 0.060 None 1.000 6 0 2010 2017
Entrez Id: 5594
Gene Symbol: MAPK1
MAPK1
P28482 mitogen-activated protein kinase 1 Kinase 1059 0.330 0.923 1.00 0.060 None 1.000 6 0 2008 2017
Entrez Id: 2100
Gene Symbol: ESR2
ESR2
Q92731 estrogen receptor 2 Nuclear receptor 528 0.400 0.923 4.5E-08 0.350 None 1.000 6 0 2009 2017
Entrez Id: 2526
Gene Symbol: FUT4
FUT4
P22083 fucosyltransferase 4 Enzyme 168 0.505 0.731 7.7E-06 0.060 None 1.000 6 0 2009 2019
Entrez Id: 3479
Gene Symbol: IGF1
IGF1
P05019 insulin like growth factor 1 1206 0.318 0.885 0.27 0.060 None 1.000 6 0 2001 2016
Entrez Id: 3480
Gene Symbol: IGF1R
IGF1R
P08069 insulin like growth factor 1 receptor Kinase 556 0.399 0.885 0.97 0.060 None 1.000 6 0 2001 2016
Entrez Id: 92737
Gene Symbol: DNER
DNER
Q8NFT8 delta/notch like EGF repeat containing 203 0.493 0.769 0.19 0.060 None 1.000 6 0 2013 2019
Entrez Id: 8743
Gene Symbol: TNFSF10
TNFSF10
P50591 TNF superfamily member 10 Signaling 445 0.413 0.885 0.13 0.060 None 1.000 6 0 2006 2012