Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3643
Gene Symbol: INSR
INSR
P06213 insulin receptor Kinase 452 0.432 0.846 3.6E-05 0.090 None 1.000 9 1 1996 2017
Entrez Id: 4023
Gene Symbol: LPL
LPL
P06858 lipoprotein lipase Enzyme 290 0.474 0.808 1.3E-09 0.090 None 1.000 9 4 1989 2019
Entrez Id: 10891
Gene Symbol: PPARGC1A
PPARGC1A
Q9UBK2 PPARG coactivator 1 alpha Transcription factor 350 0.453 0.885 1.00 0.090 None 1.000 9 1 2006 2019
Entrez Id: 55908
Gene Symbol: ANGPTL8
ANGPTL8
Q6UXH0 angiopoietin like 8 54 0.650 0.577 6.9E-12 0.090 None 1.000 9 0 2017 2019
Entrez Id: 6319
Gene Symbol: SCD
SCD
O00767 stearoyl-CoA desaturase 225 0.490 0.808 0.97 0.080 None 1.000 8 0 2004 2019
Entrez Id: 2740
Gene Symbol: GLP1R
GLP1R
P43220 glucagon like peptide 1 receptor G-protein coupled receptor 288 0.471 0.846 0.29 0.080 None 1.000 8 0 2017 2019
Entrez Id: 8856
Gene Symbol: NR1I2
NR1I2
O75469 nuclear receptor subfamily 1 group I member 2 Nuclear receptor 462 0.418 0.846 7.3E-09 0.080 None 0.875 8 0 2014 2019
Entrez Id: 5054
Gene Symbol: SERPINE1
SERPINE1
P05121 serpin family E member 1 Enzyme modulator 770 0.359 0.885 4.4E-02 0.080 None 1.000 8 0 1998 2017
Entrez Id: 3290
Gene Symbol: HSD11B1
HSD11B1
P28845 hydroxysteroid 11-beta dehydrogenase 1 163 0.520 0.731 0.42 0.080 None 1.000 8 0 2010 2019
Entrez Id: 51548
Gene Symbol: SIRT6
SIRT6
Q8N6T7 sirtuin 6 Epigenetic regulator 195 0.496 0.846 3.9E-02 0.080 None 1.000 8 0 2017 2019
Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2
Q16236 nuclear factor, erythroid 2 like 2 Enzyme 823 0.357 0.885 3.6E-03 0.070 None 1.000 7 0 2011 2019
Entrez Id: 5444
Gene Symbol: PON1
PON1
P27169 paraoxonase 1 496 0.409 0.885 9.8E-11 0.360 None 1.000 7 1 2010 2019
Entrez Id: 338557
Gene Symbol: FFAR4
FFAR4
Q5NUL3 free fatty acid receptor 4 67 0.621 0.577 1.4E-05 0.070 None 1.000 7 0 2016 2019
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.070 None 1.000 7 0 2014 2019
Entrez Id: 8862
Gene Symbol: APLN
APLN
Q9ULZ1 apelin 226 0.497 0.769 0.46 0.060 None 1.000 6 0 2013 2019
Entrez Id: 2475
Gene Symbol: MTOR
MTOR
P42345 mechanistic target of rapamycin kinase Kinase 960 0.343 0.885 1.00 0.060 None 1.000 6 0 2006 2020
Entrez Id: 846
Gene Symbol: CASR
CASR
P41180 calcium sensing receptor G-protein coupled receptor 517 0.410 0.846 4.7E-02 0.060 None 1.000 6 0 2010 2019
Entrez Id: 79068
Gene Symbol: FTO
FTO
Q9C0B1 FTO alpha-ketoglutarate dependent dioxygenase 286 0.486 0.885 8.4E-08 0.060 None 1.000 6 1 2011 2019
Entrez Id: 222545
Gene Symbol: GPRC6A
GPRC6A
Q5T6X5 G protein-coupled receptor class C group 6 member A G-protein coupled receptor 173 0.526 0.923 5.6E-17 0.060 None 1.000 6 0 2016 2018
Entrez Id: 6513
Gene Symbol: SLC2A1
SLC2A1
P11166 solute carrier family 2 member 1 Transporter 687 0.388 0.808 0.99 0.060 None 1.000 6 0 2003 2019
Entrez Id: 5770
Gene Symbol: PTPN1
PTPN1
P18031 protein tyrosine phosphatase non-receptor type 1 169 0.523 0.731 0.81 0.060 None 1.000 6 0 2006 2016
Entrez Id: 196
Gene Symbol: AHR
AHR
P35869 aryl hydrocarbon receptor Transcription factor 532 0.410 0.923 1.00 0.350 None 1.000 6 0 2015 2020
Entrez Id: 3934
Gene Symbol: LCN2
LCN2
P80188 lipocalin 2 Enzyme 497 0.405 0.885 1.1E-09 0.060 None 1.000 6 0 2016 2019
Entrez Id: 185
Gene Symbol: AGTR1
AGTR1
P30556 angiotensin II receptor type 1 G-protein coupled receptor 440 0.423 0.846 5.3E-04 0.060 None 1.000 6 0 2014 2018
Entrez Id: 3953
Gene Symbol: LEPR
LEPR
P48357 leptin receptor Signaling 416 0.433 0.808 0.99 0.060 None 1.000 6 0 2001 2018