Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 55835
Gene Symbol: CENPJ
CENPJ 		Q9HC77 centromere protein J Enzyme 150 0.546 0.846 2.1E-27 0.200 None 0 0
Entrez Id: 545
Gene Symbol: ATR
ATR 		Q13535 ATR serine/threonine kinase Kinase 321 0.456 0.923 3.5E-09 0.200 None 0 0
Entrez Id: 80254
Gene Symbol: CEP63
CEP63 		Q96MT8 centrosomal protein 63 Cellular structure 44 0.666 0.500 6.2E-25 0.200 None 0 0
Entrez Id: 317
Gene Symbol: APAF1
APAF1 		O14727 apoptotic peptidase activating factor 1 145 0.525 0.769 9.6E-06 0.200 None 0 0
Entrez Id: 56731
Gene Symbol: SLC2A4RG
SLC2A4RG 		Q9NR83 SLC2A4 regulator Transcription factor 66 0.615 0.692 0.22 0.010 None < 0.001 1 0 2014 2014
Entrez Id: 9181
Gene Symbol: ARHGEF2
ARHGEF2 		Q92974 Rho/Rac guanine nucleotide exchange factor 2 205 0.502 0.769 1.00 0.010 None < 0.001 1 0 2014 2014
Entrez Id: 2688
Gene Symbol: GH1
GH1 		P01241 growth hormone 1 Signaling 686 0.373 0.923 3.0E-02 0.100 None 0.947 19 1 2004 2020
Entrez Id: 8036
Gene Symbol: SHOC2
SHOC2 		Q9UQ13 SHOC2 leucine rich repeat scaffold protein 97 0.593 0.769 1.00 0.800 disputed 0.957 23 1 2009 2019
Entrez Id: 6654
Gene Symbol: SOS1
SOS1 		Q07889 SOS Ras/Rac guanine nucleotide exchange factor 1 Enzyme modulator 261 0.485 0.808 1.00 1.000 definitive 0.969 64 23 1991 2019
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		P01116 KRAS proto-oncogene, GTPase Enzyme modulator 1213 0.320 0.923 7.9E-04 1.000 definitive 0.985 68 17 1993 2019
Entrez Id: 5781
Gene Symbol: PTPN11
PTPN11 		Q06124 protein tyrosine phosphatase non-receptor type 11 702 0.385 0.923 1.00 1.000 definitive 0.987 301 58 2001 2020
Entrez Id: 5894
Gene Symbol: RAF1
RAF1 		P04049 Raf-1 proto-oncogene, serine/threonine kinase Kinase 470 0.418 0.885 0.85 1.000 definitive 1.000 59 19 1992 2019
Entrez Id: 673
Gene Symbol: BRAF
BRAF 		P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1228 0.319 0.846 1.00 0.770 moderate 1.000 34 18 2003 2019
Entrez Id: 6016
Gene Symbol: RIT1
RIT1 		Q92963 Ras like without CAAX 1 Enzyme modulator 184 0.527 0.808 0.13 0.900 definitive 1.000 22 13 2013 2019
Entrez Id: 4893
Gene Symbol: NRAS
NRAS 		P01111 NRAS proto-oncogene, GTPase Enzyme modulator 611 0.390 0.808 0.49 0.780 definitive 1.000 21 4 2000 2019
Entrez Id: 867
Gene Symbol: CBL
CBL 		P22681 Cbl proto-oncogene Enzyme 172 0.527 0.769 6.1E-04 0.460 strong 1.000 16 4 2009 2016
Entrez Id: 8216
Gene Symbol: LZTR1
LZTR1 		Q8N653 leucine zipper like transcription regulator 1 152 0.547 0.808 1.0E-92 0.900 strong 1.000 14 1 2014 2020
Entrez Id: 5604
Gene Symbol: MAP2K1
MAP2K1 		Q02750 mitogen-activated protein kinase kinase 1 Kinase 389 0.439 0.846 0.90 0.680 limited 1.000 14 3 2007 2019
Entrez Id: 5605
Gene Symbol: MAP2K2
MAP2K2 		P36507 mitogen-activated protein kinase kinase 2 Kinase 177 0.534 0.731 0.97 0.640 limited 1.000 11 2 2007 2019
Entrez Id: 5594
Gene Symbol: MAPK1
MAPK1 		P28482 mitogen-activated protein kinase 1 Kinase 1059 0.330 0.923 1.00 0.100 None 1.000 10 0 2007 2017
Entrez Id: 2048
Gene Symbol: EPHB2
EPHB2 		P29323 EPH receptor B2 Kinase 649 0.374 0.846 1.00 0.100 None 1.000 10 1 2007 2017
Entrez Id: 3265
Gene Symbol: HRAS
HRAS 		P01112 HRas proto-oncogene, GTPase Enzyme modulator 698 0.378 0.885 8.0E-02 0.640 1.000 8 4 2006 2018
Entrez Id: 22808
Gene Symbol: MRAS
MRAS 		O14807 muscle RAS oncogene homolog Enzyme modulator 113 0.590 0.731 0.92 0.560 limited 1.000 8 1 2013 2019
Entrez Id: 4763
Gene Symbol: NF1
NF1 		P21359 neurofibromin 1 Enzyme modulator 380 0.440 0.885 0.90 0.350 strong 1.000 6 3 1993 2013
Entrez Id: 52
Gene Symbol: ACP1
ACP1 		P24666 acid phosphatase 1 107 0.566 0.731 1.8E-08 0.050 None 1.000 5 0 2002 2007