Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 545
Gene Symbol: ATR
ATR 		Q13535 ATR serine/threonine kinase Kinase 321 0.456 0.923 3.5E-09 0.200 None 0 0
Entrez Id: 55835
Gene Symbol: CENPJ
CENPJ 		Q9HC77 centromere protein J Enzyme 150 0.546 0.846 2.1E-27 0.200 None 0 0
Entrez Id: 317
Gene Symbol: APAF1
APAF1 		O14727 apoptotic peptidase activating factor 1 145 0.525 0.769 9.6E-06 0.200 None 0 0
Entrez Id: 80254
Gene Symbol: CEP63
CEP63 		Q96MT8 centrosomal protein 63 Cellular structure 44 0.666 0.500 6.2E-25 0.200 None 0 0
Entrez Id: 6654
Gene Symbol: SOS1
SOS1 		Q07889 SOS Ras/Rac guanine nucleotide exchange factor 1 Enzyme modulator 261 0.485 0.808 1.00 1.000 definitive 0.969 64 23 1991 2019
Entrez Id: 5894
Gene Symbol: RAF1
RAF1 		P04049 Raf-1 proto-oncogene, serine/threonine kinase Kinase 470 0.418 0.885 0.85 1.000 definitive 1.000 59 19 1992 2019
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		P01116 KRAS proto-oncogene, GTPase Enzyme modulator 1213 0.320 0.923 7.9E-04 1.000 definitive 0.985 68 17 1993 2019
Entrez Id: 4763
Gene Symbol: NF1
NF1 		P21359 neurofibromin 1 Enzyme modulator 380 0.440 0.885 0.90 0.350 strong 1.000 6 3 1993 2013
Entrez Id: 7391
Gene Symbol: USF1
USF1 		P22415 upstream transcription factor 1 82 0.592 0.692 2.4E-02 0.010 None 1.000 1 0 1999 1999
Entrez Id: 4893
Gene Symbol: NRAS
NRAS 		P01111 NRAS proto-oncogene, GTPase Enzyme modulator 611 0.390 0.808 0.49 0.780 definitive 1.000 21 4 2000 2019
Entrez Id: 6655
Gene Symbol: SOS2
SOS2 		Q07890 SOS Ras/Rho guanine nucleotide exchange factor 2 Enzyme modulator 92 0.608 0.692 1.00 0.620 moderate 1.000 4 0 2000 2015
Entrez Id: 6128
Gene Symbol: RPL6
RPL6 		Q02878 ribosomal protein L6 Nucleic acid binding 27 0.700 0.385 0.99 0.010 None 1.000 1 1 2000 2000
Entrez Id: 1840
Gene Symbol: DTX1
DTX1 		Q86Y01 deltex E3 ubiquitin ligase 1 Enzyme 38 0.656 0.500 9.9E-04 0.010 None 1.000 1 0 2000 2000
Entrez Id: 5781
Gene Symbol: PTPN11
PTPN11 		Q06124 protein tyrosine phosphatase non-receptor type 11 702 0.385 0.923 1.00 1.000 definitive 0.987 301 58 2001 2020
Entrez Id: 5728
Gene Symbol: PTEN
PTEN 		P60484 phosphatase and tensin homolog Enzyme 1349 0.305 0.923 0.26 0.050 None 1.000 5 6 2002 2007
Entrez Id: 52
Gene Symbol: ACP1
ACP1 		P24666 acid phosphatase 1 107 0.566 0.731 1.8E-08 0.050 None 1.000 5 0 2002 2007
Entrez Id: 995
Gene Symbol: CDC25C
CDC25C 		P30307 cell division cycle 25C Enzyme 95 0.576 0.769 4.1E-13 0.010 None 1.000 1 0 2002 2002
Entrez Id: 146059
Gene Symbol: CDAN1
CDAN1 		Q8IWY9 codanin 1 77 0.610 0.731 1.1E-12 0.010 None 1.000 1 0 2002 2002
Entrez Id: 673
Gene Symbol: BRAF
BRAF 		P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1228 0.319 0.846 1.00 0.770 moderate 1.000 34 18 2003 2019
Entrez Id: 2688
Gene Symbol: GH1
GH1 		P01241 growth hormone 1 Signaling 686 0.373 0.923 3.0E-02 0.100 None 0.947 19 1 2004 2020
Entrez Id: 5250
Gene Symbol: SLC25A3
SLC25A3 		Q00325 solute carrier family 25 member 3 Transporter 112 0.566 0.692 7.5E-02 0.040 None 1.000 4 0 2005 2017
Entrez Id: 10076
Gene Symbol: PTPRU
PTPRU 		Q92729 protein tyrosine phosphatase receptor type U Enzyme 88 0.581 0.654 0.39 0.040 None 1.000 4 0 2005 2017
Entrez Id: 5967
Gene Symbol: REG1A
REG1A 		P05451 regenerating family member 1 alpha 264 0.467 0.846 1.3E-05 0.040 None 1.000 4 0 2005 2017
Entrez Id: 3265
Gene Symbol: HRAS
HRAS 		P01112 HRas proto-oncogene, GTPase Enzyme modulator 698 0.378 0.885 8.0E-02 0.640 1.000 8 4 2006 2018
Entrez Id: 5604
Gene Symbol: MAP2K1
MAP2K1 		Q02750 mitogen-activated protein kinase kinase 1 Kinase 389 0.439 0.846 0.90 0.680 limited 1.000 14 3 2007 2019