Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 998
Gene Symbol: CDC42
CDC42
P60953 cell division cycle 42 Enzyme modulator 327 0.458 0.846 0.79 0.020 None 1.000 2 0 2018 2018
Entrez Id: 6348
Gene Symbol: CCL3
CCL3
P10147 C-C motif chemokine ligand 3 Signaling 282 0.460 0.885 0.35 0.010 None 1.000 1 0 2016 2016
Entrez Id: 5967
Gene Symbol: REG1A
REG1A
P05451 regenerating family member 1 alpha 264 0.467 0.846 1.3E-05 0.040 None 1.000 4 0 2005 2017
Entrez Id: 27352
Gene Symbol: SGSM3
SGSM3
Q96HU1 small G protein signaling modulator 3 Enzyme 259 0.469 0.808 3.4E-15 0.010 None 1.000 1 0 2007 2007
Entrez Id: 79594
Gene Symbol: MUL1
MUL1
Q969V5 mitochondrial E3 ubiquitin protein ligase 1 241 0.473 0.808 1.9E-06 0.020 None 1.000 2 0 2010 2015
Entrez Id: 158506
Gene Symbol: CBLL2
CBLL2
Q8N7E2 Cbl proto-oncogene like 2 Enzyme 235 0.476 0.808 0.020 None 1.000 2 0 2010 2015
Entrez Id: 268
Gene Symbol: AMH
AMH
P03971 anti-Mullerian hormone 242 0.476 0.846 3.4E-12 0.010 None 1.000 1 0 2018 2018
Entrez Id: 5921
Gene Symbol: RASA1
RASA1
P20936 RAS p21 protein activator 1 Enzyme modulator 237 0.481 0.885 1.00 0.300 disputed 1.000 1 0 2016 2016
Entrez Id: 6654
Gene Symbol: SOS1
SOS1
Q07889 SOS Ras/Rac guanine nucleotide exchange factor 1 Enzyme modulator 261 0.485 0.808 1.00 1.000 definitive 0.969 64 23 1991 2019
Entrez Id: 6037
Gene Symbol: RNASE3
RNASE3
P12724 ribonuclease A family member 3 207 0.490 0.808 0.010 None 1.000 1 0 2018 2018
Entrez Id: 6197
Gene Symbol: RPS6KA3
RPS6KA3
P51812 ribosomal protein S6 kinase A3 Kinase 315 0.491 0.846 1.00 0.010 None 1.000 1 0 2014 2014
Entrez Id: 406971
Gene Symbol: MIR195
MIR195
microRNA 195 180 0.496 0.769 0.010 None 1.000 1 0 2018 2018
Entrez Id: 1969
Gene Symbol: EPHA2
EPHA2
P29317 EPH receptor A2 Kinase 187 0.501 0.731 1.1E-05 0.310 None 1.000 2 0 2012 2013
Entrez Id: 9181
Gene Symbol: ARHGEF2
ARHGEF2
Q92974 Rho/Rac guanine nucleotide exchange factor 2 205 0.502 0.769 1.00 0.010 None < 0.001 1 0 2014 2014
Entrez Id: 22882
Gene Symbol: ZHX2
ZHX2
Q9Y6X8 zinc fingers and homeoboxes 2 Transcription factor 172 0.510 0.654 3.4E-02 0.050 None 1.000 5 1 2011 2018
Entrez Id: 2904
Gene Symbol: GRIN2B
GRIN2B
Q13224 glutamate ionotropic receptor NMDA type subunit 2B Ion channel 249 0.510 0.692 1.00 0.010 None 1.000 1 0 2018 2018
Entrez Id: 5770
Gene Symbol: PTPN1
PTPN1
P18031 protein tyrosine phosphatase non-receptor type 1 169 0.523 0.731 0.81 0.010 None 1.000 1 0 2007 2007
Entrez Id: 23522
Gene Symbol: KAT6B
KAT6B
Q8WYB5 lysine acetyltransferase 6B Enzyme 208 0.525 0.731 1.00 0.310 None 1.000 1 0 2011 2011
Entrez Id: 317
Gene Symbol: APAF1
APAF1
O14727 apoptotic peptidase activating factor 1 145 0.525 0.769 9.6E-06 0.200 None 0 0
Entrez Id: 6016
Gene Symbol: RIT1
RIT1
Q92963 Ras like without CAAX 1 Enzyme modulator 184 0.527 0.808 0.13 0.900 definitive 1.000 22 13 2013 2019
Entrez Id: 867
Gene Symbol: CBL
CBL
P22681 Cbl proto-oncogene Enzyme 172 0.527 0.769 6.1E-04 0.460 strong 1.000 16 4 2009 2016
Entrez Id: 2273
Gene Symbol: FHL1
FHL1
Q13642 four and a half LIM domains 1 195 0.532 0.731 0.97 0.010 None 1.000 1 0 2013 2013
Entrez Id: 5605
Gene Symbol: MAP2K2
MAP2K2
P36507 mitogen-activated protein kinase kinase 2 Kinase 177 0.534 0.731 0.97 0.640 limited 1.000 11 2 2007 2019
Entrez Id: 90
Gene Symbol: ACVR1
ACVR1
Q04771 activin A receptor type 1 Kinase 144 0.535 0.731 0.33 0.010 None 1.000 1 0 2016 2016
Entrez Id: 2002
Gene Symbol: ELK1
ELK1
P19419 ETS transcription factor ELK1 Transcription factor 114 0.537 0.692 0.94 0.010 None 1.000 1 0 2013 2013