Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 147409
Gene Symbol: DSG4
DSG4 		Q86SJ6 desmoglein 4 Cell adhesion 40 0.686 0.423 5.9E-13 0.010 None 1.000 1 0 2014 2014
Entrez Id: 80254
Gene Symbol: CEP63
CEP63 		Q96MT8 centrosomal protein 63 Cellular structure 44 0.666 0.500 6.2E-25 0.200 None 0 0
Entrez Id: 867
Gene Symbol: CBL
CBL 		P22681 Cbl proto-oncogene Enzyme 172 0.527 0.769 6.1E-04 0.460 strong 1.000 16 4 2009 2016
Entrez Id: 5500
Gene Symbol: PPP1CB
PPP1CB 		P62140 protein phosphatase 1 catalytic subunit beta Enzyme 105 0.601 0.577 1.00 0.350 1.000 5 0 2016 2019
Entrez Id: 5728
Gene Symbol: PTEN
PTEN 		P60484 phosphatase and tensin homolog Enzyme 1349 0.305 0.923 0.26 0.050 None 1.000 5 6 2002 2007
Entrez Id: 10076
Gene Symbol: PTPRU
PTPRU 		Q92729 protein tyrosine phosphatase receptor type U Enzyme 88 0.581 0.654 0.39 0.040 None 1.000 4 0 2005 2017
Entrez Id: 158506
Gene Symbol: CBLL2
CBLL2 		Q8N7E2 Cbl proto-oncogene like 2 Enzyme 235 0.476 0.808 0.020 None 1.000 2 0 2010 2015
Entrez Id: 5071
Gene Symbol: PRKN
PRKN 		O60260 parkin RBR E3 ubiquitin protein ligase Enzyme 409 0.431 0.846 6.9E-07 0.020 None 1.000 2 0 2010 2015
Entrez Id: 11122
Gene Symbol: PTPRT
PTPRT 		O14522 protein tyrosine phosphatase receptor type T Enzyme 53 0.636 0.538 1.00 0.010 None 1.000 1 0 2017 2017
Entrez Id: 1840
Gene Symbol: DTX1
DTX1 		Q86Y01 deltex E3 ubiquitin ligase 1 Enzyme 38 0.656 0.500 9.9E-04 0.010 None 1.000 1 0 2000 2000
Entrez Id: 23522
Gene Symbol: KAT6B
KAT6B 		Q8WYB5 lysine acetyltransferase 6B Enzyme 208 0.525 0.731 1.00 0.310 None 1.000 1 0 2011 2011
Entrez Id: 27352
Gene Symbol: SGSM3
SGSM3 		Q96HU1 small G protein signaling modulator 3 Enzyme 259 0.469 0.808 3.4E-15 0.010 None 1.000 1 0 2007 2007
Entrez Id: 995
Gene Symbol: CDC25C
CDC25C 		P30307 cell division cycle 25C Enzyme 95 0.576 0.769 4.1E-13 0.010 None 1.000 1 0 2002 2002
Entrez Id: 55835
Gene Symbol: CENPJ
CENPJ 		Q9HC77 centromere protein J Enzyme 150 0.546 0.846 2.1E-27 0.200 None 0 0
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		P01116 KRAS proto-oncogene, GTPase Enzyme modulator 1213 0.320 0.923 7.9E-04 1.000 definitive 0.985 68 17 1993 2019
Entrez Id: 6654
Gene Symbol: SOS1
SOS1 		Q07889 SOS Ras/Rac guanine nucleotide exchange factor 1 Enzyme modulator 261 0.485 0.808 1.00 1.000 definitive 0.969 64 23 1991 2019
Entrez Id: 6016
Gene Symbol: RIT1
RIT1 		Q92963 Ras like without CAAX 1 Enzyme modulator 184 0.527 0.808 0.13 0.900 definitive 1.000 22 13 2013 2019
Entrez Id: 4893
Gene Symbol: NRAS
NRAS 		P01111 NRAS proto-oncogene, GTPase Enzyme modulator 611 0.390 0.808 0.49 0.780 definitive 1.000 21 4 2000 2019
Entrez Id: 22808
Gene Symbol: MRAS
MRAS 		O14807 muscle RAS oncogene homolog Enzyme modulator 113 0.590 0.731 0.92 0.560 limited 1.000 8 1 2013 2019
Entrez Id: 3265
Gene Symbol: HRAS
HRAS 		P01112 HRas proto-oncogene, GTPase Enzyme modulator 698 0.378 0.885 8.0E-02 0.640 1.000 8 4 2006 2018
Entrez Id: 4763
Gene Symbol: NF1
NF1 		P21359 neurofibromin 1 Enzyme modulator 380 0.440 0.885 0.90 0.350 strong 1.000 6 3 1993 2013
Entrez Id: 6655
Gene Symbol: SOS2
SOS2 		Q07890 SOS Ras/Rho guanine nucleotide exchange factor 2 Enzyme modulator 92 0.608 0.692 1.00 0.620 moderate 1.000 4 0 2000 2015
Entrez Id: 144568
Gene Symbol: A2ML1
A2ML1 		A8K2U0 alpha-2-macroglobulin like 1 Enzyme modulator 94 0.590 0.692 1.6E-34 0.600 disputed 1.000 3 0 2015 2016
Entrez Id: 22800
Gene Symbol: RRAS2
RRAS2 		P62070 RAS related 2 Enzyme modulator 48 0.656 0.500 0.97 0.620 strong 1.000 3 0 2014 2019
Entrez Id: 6237
Gene Symbol: RRAS
RRAS 		P10301 RAS related Enzyme modulator 149 0.543 0.808 4.7E-03 0.510 limited 1.000 2 1 2013 2014