Source: CURATED ×
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 6622
Gene Symbol: SNCA
SNCA 		P37840 synuclein alpha Transporter 36 0.427 0.885 0.88 0.700 None 0.983 29 34 1997 2020
Entrez Id: 5071
Gene Symbol: PRKN
PRKN 		O60260 parkin RBR E3 ubiquitin protein ligase Enzyme 42 0.431 0.846 6.9E-07 0.600 None 0.974 13 0 1998 2020
Entrez Id: 11315
Gene Symbol: PARK7
PARK7 		Q99497 Parkinsonism associated deglycase Enzyme 25 0.535 0.808 0.75 0.600 None 0.973 9 0 2003 2020
Entrez Id: 65018
Gene Symbol: PINK1
PINK1 		Q9BXM7 PTEN induced kinase 1 Kinase 18 0.516 0.769 1.9E-10 0.600 None 0.987 5 0 2002 2020
Entrez Id: 23400
Gene Symbol: ATP13A2
ATP13A2 		Q9NQ11 ATPase cation transporting 13A2 26 0.566 0.577 9.0E-09 0.600 strong 0.946 4 0 2007 2019
Entrez Id: 1644
Gene Symbol: DDC
DDC 		P20711 dopa decarboxylase 30 0.535 0.769 3.8E-08 0.600 None 1.000 2 0 1988 2019
Entrez Id: 1813
Gene Symbol: DRD2
DRD2 		P14416 dopamine receptor D2 G-protein coupled receptor 133 0.436 0.846 0.75 0.600 None 0.931 1 0 1995 2020
Entrez Id: 7054
Gene Symbol: TH
TH 		P07101 tyrosine hydroxylase 51 0.462 0.885 1.7E-06 0.600 None 0.979 1 0 1989 2020
Entrez Id: 6571
Gene Symbol: SLC18A2
SLC18A2 		Q05940 solute carrier family 18 member A2 Transporter 21 0.554 0.769 7.6E-02 0.600 None 0.966 1 0 1996 2020
Entrez Id: 4129
Gene Symbol: MAOB
MAOB 		P27338 monoamine oxidase B 35 0.533 0.808 1.00 0.600 None 0.991 1 0 1993 2020
Entrez Id: 1812
Gene Symbol: DRD1
DRD1 		P21728 dopamine receptor D1 G-protein coupled receptor 52 0.529 0.808 0.96 0.570 None 1.000 1 0 1996 2020
Entrez Id: 3480
Gene Symbol: IGF1R
IGF1R 		P08069 insulin like growth factor 1 receptor Kinase 44 0.399 0.885 0.97 0.510 None 1.000 1 0 2009 2019
Entrez Id: 120892
Gene Symbol: LRRK2
LRRK2 		Q5S007 leucine rich repeat kinase 2 Kinase 23 0.510 0.808 2.6E-30 0.500 None 0.983 11 6 2002 2020
Entrez Id: 2629
Gene Symbol: GBA
GBA 		P04062 glucosylceramidase beta 21 0.500 0.808 1.4E-06 0.500 None 0.989 2 1 2004 2020
Entrez Id: 4137
Gene Symbol: MAPT
MAPT 		P10636 microtubule associated protein tau 66 0.446 0.923 6.0E-03 0.500 None 0.972 2 24 1999 2019
Entrez Id: 2580
Gene Symbol: GAK
GAK 		O14976 cyclin G associated kinase Kinase 1 0.805 0.231 5.2E-03 0.500 None 1.000 1 3 2009 2020
Entrez Id: 683
Gene Symbol: BST1
BST1 		Q10588 bone marrow stromal cell antigen 1 Enzyme 2 0.670 0.423 4.2E-11 0.500 None 0.920 1 7 2009 2019
Entrez Id: 3122
Gene Symbol: HLA-DRA
HLA-DRA 		P01903 major histocompatibility complex, class II, DR alpha Immune response 9 0.581 0.769 0.52 0.480 None 1.000 1 1 2010 2015
Entrez Id: 6531
Gene Symbol: SLC6A3
SLC6A3 		Q01959 solute carrier family 6 member 3 Transporter 58 0.453 0.885 1.00 0.400 None 0.935 4 0 1994 2020
Entrez Id: 6647
Gene Symbol: SOD1
SOD1 		P00441 superoxide dismutase 1 Enzyme 147 0.379 0.962 0.18 0.400 None 0.971 3 0 1993 2020
Entrez Id: 6648
Gene Symbol: SOD2
SOD2 		P04179 superoxide dismutase 2 Enzyme 285 0.379 0.923 0.15 0.400 None 1.000 3 0 1997 2019
Entrez Id: 2668
Gene Symbol: GDNF
GDNF 		P39905 glial cell derived neurotrophic factor Signaling 85 0.434 0.885 0.20 0.400 None 0.983 2 0 1993 2020
Entrez Id: 100359403
Gene Symbol: PARK16
PARK16 		Parkinson disease 16 (susceptibility) 1 0.861 0.077 0.400 None 0.963 2 0 2009 2019
Entrez Id: 1356
Gene Symbol: CP
CP 		P00450 ceruloplasmin Enzyme 75 0.466 0.846 4.2E-10 0.400 None 0.938 2 0 2004 2020
Entrez Id: 1565
Gene Symbol: CYP2D6
CYP2D6 		P10635 cytochrome P450 family 2 subfamily D member 6 93 0.437 0.885 1.1E-25 0.400 None 0.879 2 0 1992 2019