Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 1555
Gene Symbol: CYP2B6
CYP2B6
P20813 cytochrome P450 family 2 subfamily B member 6 388 0.428 0.846 1.9E-10 0.020 None 1.000 2 0 1993 1994
Entrez Id: 6794
Gene Symbol: STK11
STK11
Q15831 serine/threonine kinase 11 Kinase 372 0.435 0.808 0.99 1.000 definitive 0.992 258 77 1997 2019
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
P60484 phosphatase and tensin homolog Enzyme 1349 0.305 0.923 0.26 0.070 None 1.000 7 0 1998 2019
Entrez Id: 1820
Gene Symbol: ARID3A
ARID3A
Q99856 AT-rich interaction domain 3A Nucleic acid binding 31 0.678 0.500 0.99 0.010 None 1.000 1 0 1998 1998
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
P42771 Q8N726 cyclin dependent kinase inhibitor 2A 1314 0.300 0.885 0.39 0.030 None 1.000 3 0 1999 2015
Entrez Id: 115482713
Gene Symbol: H3P10
H3P10
H3 histone pseudogene 10 769 0.350 0.846 0.030 None 1.000 3 0 1999 2015
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
P51587 BRCA2 DNA repair associated Nucleic acid binding 656 0.379 0.846 2.4E-25 0.020 None 1.000 2 0 1999 2013
Entrez Id: 6416
Gene Symbol: MAP2K4
MAP2K4
P45985 mitogen-activated protein kinase kinase 4 Kinase 100 0.559 0.692 1.00 0.010 None 1.000 1 0 1999 1999
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
P00533 epidermal growth factor receptor Kinase 1394 0.295 0.885 0.37 0.010 None 1.000 1 0 1999 1999
Entrez Id: 5972
Gene Symbol: REN
REN
P00797 renin Enzyme 721 0.370 0.923 2.4E-07 0.010 None 1.000 1 0 1999 1999
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.080 None 1.000 8 1 2000 2018
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
P35222 catenin beta 1 1368 0.303 0.885 1.00 0.060 None 1.000 6 0 2000 2019
Entrez Id: 1588
Gene Symbol: CYP19A1
CYP19A1
P11511 cytochrome P450 family 19 subfamily A member 1 Enzyme 519 0.410 0.885 1.7E-05 0.050 None 1.000 5 0 2001 2018
Entrez Id: 4221
Gene Symbol: MEN1
MEN1
O00255 menin 1 364 0.444 0.808 1.00 0.020 None 1.000 2 0 2001 2002
Entrez Id: 324
Gene Symbol: APC
APC
P25054 APC regulator of WNT signaling pathway 703 0.373 0.962 1.00 0.020 None 1.000 2 0 2001 2019
Entrez Id: 55835
Gene Symbol: CENPJ
CENPJ
Q9HC77 centromere protein J Enzyme 150 0.546 0.846 2.1E-27 0.020 None 1.000 2 0 2001 2002
Entrez Id: 4089
Gene Symbol: SMAD4
SMAD4
Q13485 SMAD family member 4 Transcription factor 575 0.401 0.808 1.00 0.020 None 1.000 2 0 2001 2001
Entrez Id: 114790
Gene Symbol: STK11IP
STK11IP
Q8N1F8 serine/threonine kinase 11 interacting protein Enzyme modulator 7 0.861 0.192 8.6E-20 0.020 None 1.000 2 0 2001 2002
Entrez Id: 6597
Gene Symbol: SMARCA4
SMARCA4
P51532 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 Epigenetic regulator 347 0.450 0.885 1.00 0.020 None 1.000 2 0 2001 2005
Entrez Id: 8500
Gene Symbol: PPFIA1
PPFIA1
Q13136 PTPRF interacting protein alpha 1 22 0.760 0.269 1.00 0.020 None 1.000 2 0 2001 2002
Entrez Id: 11019
Gene Symbol: LIAS
LIAS
O43766 lipoic acid synthetase 43 0.695 0.538 2.3E-05 0.020 None 1.000 2 0 2001 2002
Entrez Id: 5794
Gene Symbol: PTPRH
PTPRH
Q9HD43 protein tyrosine phosphatase receptor type H Enzyme 30 0.691 0.423 1.0E-36 0.010 None 1.000 1 0 2001 2001
Entrez Id: 1045
Gene Symbol: CDX2
CDX2
Q99626 caudal type homeobox 2 Transcription factor 278 0.458 0.769 0.53 0.010 None 1.000 1 0 2001 2001
Entrez Id: 4087
Gene Symbol: SMAD2
SMAD2
Q15796 SMAD family member 2 Transcription factor 289 0.456 0.808 1.00 0.010 None 1.000 1 0 2001 2001
Entrez Id: 7428
Gene Symbol: VHL
VHL
P40337 von Hippel-Lindau tumor suppressor Enzyme 372 0.443 0.846 8.0E-02 0.010 None 1.000 1 0 2001 2001