Source: BEFREE ×
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 5265
Gene Symbol: SERPINA1
SERPINA1 		P01009 serpin family A member 1 Enzyme modulator 411 0.410 0.923 6.8E-08 0.500 None 0.978 127 2 1973 2020
Entrez Id: 260431
Gene Symbol: COPD
COPD 		Pulmonary disease, chronic obstructive, severe early-onset 349 0.456 0.885 0.100 None 0.972 71 0 1999 2020
Entrez Id: 1991
Gene Symbol: ELANE
ELANE 		P08246 elastase, neutrophil expressed Enzyme 290 0.447 0.846 1.2E-03 0.100 None 1.000 25 0 1981 2019
Entrez Id: 2006
Gene Symbol: ELN
ELN 		P15502 elastin 302 0.415 0.885 2.1E-14 0.400 None 1.000 20 0 1992 2019
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		P15692 vascular endothelial growth factor A Signaling 1737 0.266 0.923 2.4E-05 0.100 None 0.947 19 0 2001 2019
Entrez Id: 4321
Gene Symbol: MMP12
MMP12 		P39900 matrix metallopeptidase 12 Enzyme 197 0.484 0.885 0.400 None 1.000 19 1 1997 2019
Entrez Id: 4318
Gene Symbol: MMP9
MMP9 		P14780 matrix metallopeptidase 9 Enzyme 1160 0.305 0.923 1.9E-17 0.400 None 1.000 16 0 2001 2019
Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2 		Q16236 nuclear factor, erythroid 2 like 2 Enzyme 739 0.357 0.885 3.6E-03 0.100 None 1.000 13 1 2004 2019
Entrez Id: 3569
Gene Symbol: IL6
IL6 		P05231 interleukin 6 2132 0.248 0.962 0.32 0.100 None 1.000 12 0 2009 2019
Entrez Id: 4312
Gene Symbol: MMP1
MMP1 		P03956 matrix metallopeptidase 1 Enzyme 507 0.385 0.885 7.7E-18 0.100 None 1.000 11 0 1992 2015
Entrez Id: 2551
Gene Symbol: GABPA
GABPA 		Q06546 GA binding protein transcription factor subunit alpha Transcription factor 630 0.379 0.885 1.00 0.100 None 1.000 10 0 2004 2019
Entrez Id: 6441
Gene Symbol: SFTPD
SFTPD 		P35247 surfactant protein D Surfactant 179 0.500 0.846 7.5E-05 0.090 None 1.000 9 2 2002 2018
Entrez Id: 7124
Gene Symbol: TNF
TNF 		P01375 tumor necrosis factor Signaling 2475 0.231 0.962 0.80 0.390 None 1.000 9 0 2002 2019
Entrez Id: 2052
Gene Symbol: EPHX1
EPHX1 		P07099 epoxide hydrolase 1 137 0.500 0.846 3.2E-09 0.370 None 0.857 7 0 1997 2011
Entrez Id: 3458
Gene Symbol: IFNG
IFNG 		P01579 interferon gamma 1361 0.288 0.962 0.47 0.060 None 1.000 6 0 2000 2019
Entrez Id: 3553
Gene Symbol: IL1B
IL1B 		P01584 interleukin 1 beta 1604 0.276 0.962 0.13 0.060 None 0.833 6 0 2002 2018
Entrez Id: 3596
Gene Symbol: IL13
IL13 		P35225 interleukin 13 544 0.386 0.846 1.4E-02 0.060 None 1.000 6 0 2000 2020
Entrez Id: 388007
Gene Symbol: SERPINA13P
SERPINA13P 		Q6UXR4 serpin family A member 13, pseudogene 58 0.619 0.692 0.060 None 1.000 6 0 1990 2018
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1 		P01137 transforming growth factor beta 1 Signaling 1334 0.287 0.962 3.7E-02 0.360 None 1.000 6 1 2003 2017
Entrez Id: 710
Gene Symbol: SERPING1
SERPING1 		P05155 serpin family G member 1 Enzyme modulator 161 0.507 0.769 0.96 0.050 None 1.000 5 0 2002 2005
Entrez Id: 3605
Gene Symbol: IL17A
IL17A 		Q16552 interleukin 17A 1034 0.324 0.923 4.3E-02 0.050 None 1.000 5 0 2017 2019
Entrez Id: 1080
Gene Symbol: CFTR
CFTR 		P13569 CF transmembrane conductance regulator Ion channel 365 0.424 0.885 2.2E-58 0.050 None 1.000 5 0 1998 2019
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		P00533 epidermal growth factor receptor Kinase 1308 0.295 0.885 0.37 0.050 None 0.800 5 0 2013 2019
Entrez Id: 7157
Gene Symbol: TP53
TP53 		P04637 tumor protein p53 Transcription factor 2245 0.236 0.962 0.53 0.040 None 1.000 4 0 2000 2019
Entrez Id: 3791
Gene Symbol: KDR
KDR 		P35968 kinase insert domain receptor Kinase 561 0.378 0.885 1.00 0.040 None 1.000 4 0 2001 2017