Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 1471
Gene Symbol: CST3
CST3
P01034 cystatin C 370 0.436 0.808 3.9E-03 0.500 limited 1.000 11 0 1989 2020
Entrez Id: 9445
Gene Symbol: ITM2B
ITM2B
Q9Y287 integral membrane protein 2B 77 0.617 0.654 0.63 0.300 limited 1.000 1 0 2000 2000
Entrez Id: 4854
Gene Symbol: NOTCH3
NOTCH3
Q9UM47 notch receptor 3 418 0.435 0.808 0.41 0.500 strong 0.973 37 11 1996 2020
Entrez Id: 1282
Gene Symbol: COL4A1
COL4A1
P02462 collagen type IV alpha 1 chain 277 0.484 0.731 1.00 0.500 strong 1.000 15 1 2006 2020
Entrez Id: 2717
Gene Symbol: GLA
GLA
P06280 galactosidase alpha 190 0.537 0.769 1.00 0.400 strong 1.000 11 2 2004 2018
Entrez Id: 351
Gene Symbol: APP
APP
P05067 amyloid beta precursor protein Enzyme modulator 485 0.422 0.846 4.7E-02 0.490 strong 1.000 10 2 2002 2014
Entrez Id: 1281
Gene Symbol: COL3A1
COL3A1
P02461 collagen type III alpha 1 chain 301 0.477 0.808 1.00 0.310 strong 1.000 2 3 1995 2014
Entrez Id: 2296
Gene Symbol: FOXC1
FOXC1
Q12948 forkhead box C1 Transcription factor 242 0.483 0.846 0.95 0.310 strong 1.000 2 0 2013 2018
Entrez Id: 5327
Gene Symbol: PLAT
PLAT
P00750 plasminogen activator, tissue type Enzyme 392 0.445 0.885 5.7E-05 0.400 None 0.973 149 1 1989 2020
Entrez Id: 100128998
Gene Symbol: C20orf181
C20orf181
chromosome 20 open reading frame 181 246 0.479 0.885 0.100 None 0.957 115 0 1995 2020
Entrez Id: 348
Gene Symbol: APOE
APOE
P02649 apolipoprotein E 1049 0.338 0.962 1.9E-03 0.100 None 0.887 115 1 1995 2019
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
P42898 methylenetetrahydrofolate reductase 985 0.337 0.885 3.2E-10 0.500 None 0.938 97 4 1997 2019
Entrez Id: 1401
Gene Symbol: CRP
CRP
P02741 C-reactive protein 1483 0.299 0.962 3.7E-03 0.100 None 0.963 82 3 2001 2020
Entrez Id: 627
Gene Symbol: BDNF
BDNF
P23560 brain derived neurotrophic factor Signaling 992 0.345 0.923 0.66 0.100 None 0.914 81 7 2001 2020
Entrez Id: 1636
Gene Symbol: ACE
ACE
P12821 angiotensin I converting enzyme Enzyme 1082 0.328 0.923 1.0E-37 0.600 None 0.844 64 1 1994 2020
Entrez Id: 3569
Gene Symbol: IL6
IL6
P05231 interleukin 6 2367 0.248 0.962 0.32 0.400 None 0.979 48 1 1996 2020
Entrez Id: 340348
Gene Symbol: TSPAN33
TSPAN33
Q86UF1 tetraspanin 33 69 0.606 0.731 7.0E-05 0.100 None 1.000 45 0 2006 2020
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.600 None 0.956 45 2 1999 2020
Entrez Id: 5144
Gene Symbol: PDE4D
PDE4D
Q08499 phosphodiesterase 4D 210 0.519 0.846 1.00 0.300 None 0.953 43 8 2002 2018
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
P15692 vascular endothelial growth factor A Signaling 1899 0.266 0.923 2.4E-05 0.300 None 0.977 43 2 1999 2019
Entrez Id: 4018
Gene Symbol: LPA
LPA
P08519 lipoprotein(a) Enzyme 340 0.444 0.769 6.6E-89 0.500 None 1.000 41 1 1989 2019
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
P14780 matrix metallopeptidase 9 Enzyme 1337 0.305 0.923 1.9E-17 0.300 None 0.976 41 2 2003 2019
Entrez Id: 2147
Gene Symbol: F2
F2
P00734 coagulation factor II, thrombin Enzyme 490 0.415 0.885 1.1E-03 0.500 None 0.946 37 4 1995 2020
Entrez Id: 5054
Gene Symbol: SERPINE1
SERPINE1
P05121 serpin family E member 1 Enzyme modulator 770 0.359 0.885 4.4E-02 0.100 None 0.811 37 1 1996 2020
Entrez Id: 2153
Gene Symbol: F5
F5
P12259 coagulation factor V Enzyme 369 0.441 0.846 5.9E-15 0.500 None 0.971 35 2 1995 2016