Source: BEFREE ×
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 5265
Gene Symbol: SERPINA1
SERPINA1 		P01009 serpin family A member 1 Enzyme modulator 411 0.410 0.923 6.8E-08 0.400 None 0.909 10 0 1991 2018
Entrez Id: 5657
Gene Symbol: PRTN3
PRTN3 		P24158 proteinase 3 Enzyme 153 0.503 0.808 3.8E-05 0.200 None 0.907 53 0 1994 2019
Entrez Id: 51816
Gene Symbol: ADA2
ADA2 		Q9NZK5 adenosine deaminase 2 Enzyme 88 0.545 0.846 8.1E-08 0.200 None 1.000 11 0 2014 2020
Entrez Id: 3586
Gene Symbol: IL10
IL10 		P22301 interleukin 10 1533 0.281 0.923 5.9E-03 0.170 None 1.000 7 0 2003 2018
Entrez Id: 3106
Gene Symbol: HLA-B
HLA-B 		P01889 major histocompatibility complex, class I, B 492 0.379 0.885 3.9E-05 0.150 None 1.000 5 0 2000 2015
Entrez Id: 4210
Gene Symbol: MEFV
MEFV 		O15553 MEFV innate immuity regulator, pyrin 298 0.440 0.885 1.0E-14 0.140 None 1.000 4 2 2007 2019
Entrez Id: 26191
Gene Symbol: PTPN22
PTPN22 		Q9Y2R2 protein tyrosine phosphatase non-receptor type 22 238 0.438 0.846 3.5E-21 0.140 None 0.750 4 1 2005 2015
Entrez Id: 931
Gene Symbol: MS4A1
MS4A1 		P11836 membrane spanning 4-domains A1 Receptor 425 0.411 0.846 5.1E-05 0.130 None 1.000 3 0 1997 2017
Entrez Id: 7099
Gene Symbol: TLR4
TLR4 		O00206 toll like receptor 4 1030 0.321 0.962 4.6E-09 0.130 None 0.667 2 2 2009 2018
Entrez Id: 3115
Gene Symbol: HLA-DPB1
HLA-DPB1 		P04440 major histocompatibility complex, class II, DP beta 1 Immune response 234 0.453 0.923 5.3E-10 0.120 None 1.000 2 0 1993 2015
Entrez Id: 1493
Gene Symbol: CTLA4
CTLA4 		P16410 cytotoxic T-lymphocyte associated protein 4 600 0.369 0.923 0.94 0.120 None 1.000 2 0 2018 2018
Entrez Id: 114548
Gene Symbol: NLRP3
NLRP3 		Q96P20 NLR family pyrin domain containing 3 702 0.361 0.962 8.1E-04 0.120 None 1.000 2 0 2018 2020
Entrez Id: 115650
Gene Symbol: TNFRSF13C
TNFRSF13C 		Q96RJ3 TNF receptor superfamily member 13C 93 0.540 0.731 0.27 0.110 None 1.000 1 0 2009 2009
Entrez Id: 3593
Gene Symbol: IL12B
IL12B 		P29460 interleukin 12B Signaling 176 0.480 0.885 1.1E-04 0.110 None 1.000 1 0 2015 2015
Entrez Id: 4790
Gene Symbol: NFKB1
NFKB1 		P19838 nuclear factor kappa B subunit 1 Transcription factor 462 0.396 0.923 1.00 0.110 None 1.000 1 0 2006 2006
Entrez Id: 355
Gene Symbol: FAS
FAS 		P25445 Fas cell surface death receptor 526 0.372 0.923 0.81 0.110 None 1.000 1 0 2002 2002
Entrez Id: 4615
Gene Symbol: MYD88
MYD88 		Q99836 MYD88 innate immune signal transduction adaptor Enzyme modulator 411 0.414 0.923 0.12 0.110 None 1.000 1 0 2017 2017
Entrez Id: 3426
Gene Symbol: CFI
CFI 		P05156 complement factor I 60 0.569 0.731 3.5E-08 0.110 None 1.000 1 0 2018 2018
Entrez Id: 4353
Gene Symbol: MPO
MPO 		P05164 myeloperoxidase Enzyme 584 0.377 0.923 7.1E-15 0.100 None 0.971 67 1 1994 2020
Entrez Id: 7124
Gene Symbol: TNF
TNF 		P01375 tumor necrosis factor Signaling 2475 0.231 0.962 0.80 0.100 None 1.000 19 0 1990 2019
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1 		P01911 major histocompatibility complex, class II, DR beta 1 Immune response 839 0.333 0.923 1.1E-03 0.100 None 0.917 12 0 1991 2016
Entrez Id: 3553
Gene Symbol: IL1B
IL1B 		P01584 interleukin 1 beta 1604 0.276 0.962 0.13 0.100 None 1.000 10 0 1996 2020
Entrez Id: 23583
Gene Symbol: SMUG1
SMUG1 		Q53HV7 single-strand-selective monofunctional uracil-DNA glycosylase 1 1029 0.322 0.923 4.5E-04 0.080 None 1.000 8 0 2017 2019
Entrez Id: 60498
Gene Symbol: IGAN1
IGAN1 		IgA nephropathy 140 0.524 0.808 0.080 None 1.000 8 0 1988 2020
Entrez Id: 3569
Gene Symbol: IL6
IL6 		P05231 interleukin 6 2132 0.248 0.962 0.32 0.070 None 1.000 7 0 2012 2019