Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 2263
Gene Symbol: FGFR2
FGFR2
P21802 fibroblast growth factor receptor 2 Kinase 82 0.380 0.808 1.00 0.630 None 0.750 1 2 2013 2016
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
P00533 epidermal growth factor receptor Kinase 23 0.295 0.885 0.37 0.500 None 0.980 4 5 2007 2019
Entrez Id: 4921
Gene Symbol: DDR2
DDR2
Q16832 discoidin domain receptor tyrosine kinase 2 Kinase 6 0.541 0.769 0.55 0.490 None 1.000 1 5 2011 2019
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
P01116 KRAS proto-oncogene, GTPase Enzyme modulator 66 0.320 0.923 7.9E-04 0.430 None 1.000 1 2 2014 2019
Entrez Id: 1969
Gene Symbol: EPHA2
EPHA2
P29317 EPH receptor A2 Kinase 2 0.501 0.731 1.1E-05 0.410 None 1.000 1 1 2010 2019
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 85 0.292 0.923 1.00 0.200 None 1.000 1 17 2014 2018
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 84 0.236 0.962 0.53 0.200 None 1.000 1 62 1994 2019
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
P42771 Q8N726 cyclin dependent kinase inhibitor 2A 22 0.300 0.885 0.39 0.200 None 1.000 1 4 2000 2019
Entrez Id: 673
Gene Symbol: BRAF
BRAF
P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 125 0.319 0.846 1.00 0.160 None 1.000 1 3 2007 2019
Entrez Id: 2261
Gene Symbol: FGFR3
FGFR3
P22607 fibroblast growth factor receptor 3 Kinase 60 0.391 0.846 1.6E-05 0.160 None 1.000 1 2 2013 2019
Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2
Q16236 nuclear factor, erythroid 2 like 2 Enzyme 10 0.357 0.885 3.6E-03 0.150 None 0.833 1 5 2010 2017
Entrez Id: 6794
Gene Symbol: STK11
STK11
Q15831 serine/threonine kinase 11 Kinase 22 0.435 0.808 0.99 0.120 None 0.667 1 3 2007 2019
Entrez Id: 55294
Gene Symbol: FBXW7
FBXW7
Q969H0 F-box and WD repeat domain containing 7 Enzyme modulator 18 0.465 0.808 1.00 0.110 None 1.000 1 6 2016 2019
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
P01112 HRas proto-oncogene, GTPase Enzyme modulator 71 0.378 0.885 8.0E-02 0.110 None 1.000 1 5 1985 2016
Entrez Id: 2033
Gene Symbol: EP300
EP300
Q09472 E1A binding protein p300 28 0.459 0.846 1.00 0.110 None 1.000 1 1 2016 2017
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
P60484 phosphatase and tensin homolog Enzyme 107 0.305 0.923 0.26 0.110 None 1.000 1 2 2016 2017
Entrez Id: 100507500
Gene Symbol: EGFR-AS1
EGFR-AS1
EGFR antisense RNA 1 5 0.722 0.192 0.100 None 1.000 2 1 2012 2013
Entrez Id: 567
Gene Symbol: B2M
B2M
P61769 beta-2-microglobulin Immune response 12 0.447 0.846 0.56 0.100 None 1.000 1 3 2016 2016
Entrez Id: 5781
Gene Symbol: PTPN11
PTPN11
Q06124 protein tyrosine phosphatase non-receptor type 11 153 0.385 0.923 1.00 0.100 None 1.000 1 3 2016 2016
Entrez Id: 5537
Gene Symbol: PPP6C
PPP6C
O00743 protein phosphatase 6 catalytic subunit 2 0.729 0.231 0.86 0.100 None 1.000 1 1 2016 2016
Entrez Id: 1387
Gene Symbol: CREBBP
CREBBP
Q92793 CREB binding protein 40 0.428 0.808 1.00 0.100 None 1.000 1 2 2016 2016
Entrez Id: 9968
Gene Symbol: MED12
MED12
Q93074 mediator complex subunit 12 Transcription factor 25 0.476 0.769 1.00 0.100 None 1.000 1 1 2016 2016