Source: CLINVAR ×
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2263
Gene Symbol: FGFR2
FGFR2 		0.630 GeneticVariation disease CLINVAR Inhibitor-sensitive FGFR2 and FGFR3 mutations in lung squamous cell carcinoma. 23786770 2013
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		0.500 GeneticVariation disease CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		0.500 GeneticVariation disease CLINVAR MEK inhibitors reverse resistance in epidermal growth factor receptor mutation lung cancer cells with acquired resistance to gefitinib. 23102728 2013
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		0.500 GeneticVariation disease CLINVAR Randomized phase II study of dacomitinib (PF-00299804), an irreversible pan-human epidermal growth factor receptor inhibitor, versus erlotinib in patients with advanced non-small-cell lung cancer. 22753918 2012
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		0.500 CausalMutation disease CLINVAR Clinical implications of novel activating EGFR mutations in malignant peritoneal mesothelioma. 20942962 2010
Entrez Id: 4921
Gene Symbol: DDR2
DDR2 		0.490 GeneticVariation disease CLINVAR Mutations in the DDR2 kinase gene identify a novel therapeutic target in squamous cell lung cancer. 22328973 2011
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		0.430 GeneticVariation disease CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		0.430 CausalMutation disease CLINVAR
Entrez Id: 1969
Gene Symbol: EPHA2
EPHA2 		0.410 GeneticVariation disease CLINVAR EphA2 mutation in lung squamous cell carcinoma promotes increased cell survival, cell invasion, focal adhesions, and mammalian target of rapamycin activation. 20360610 2010
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.200 GeneticVariation disease CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A 		0.200 GeneticVariation disease CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA 		0.200 GeneticVariation disease CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
Entrez Id: 2261
Gene Symbol: FGFR3
FGFR3 		0.160 GeneticVariation disease CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
Entrez Id: 673
Gene Symbol: BRAF
BRAF 		0.160 GeneticVariation disease CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2 		0.150 GeneticVariation disease CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
Entrez Id: 6794
Gene Symbol: STK11
STK11 		0.120 GeneticVariation disease CLINVAR LKB1 modulates lung cancer differentiation and metastasis. 17676035 2007
Entrez Id: 5728
Gene Symbol: PTEN
PTEN 		0.110 GeneticVariation disease CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
Entrez Id: 3265
Gene Symbol: HRAS
HRAS 		0.110 GeneticVariation disease CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
Entrez Id: 55294
Gene Symbol: FBXW7
FBXW7 		0.110 GeneticVariation disease CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
Entrez Id: 2033
Gene Symbol: EP300
EP300 		0.110 GeneticVariation disease CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
Entrez Id: 567
Gene Symbol: B2M
B2M 		0.100 GeneticVariation disease CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
Entrez Id: 1387
Gene Symbol: CREBBP
CREBBP 		0.100 GeneticVariation disease CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
Entrez Id: 5781
Gene Symbol: PTPN11
PTPN11 		0.100 GeneticVariation disease CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
Entrez Id: 5537
Gene Symbol: PPP6C
PPP6C 		0.100 GeneticVariation disease CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
Entrez Id: 9968
Gene Symbol: MED12
MED12 		0.100 GeneticVariation disease CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016