Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
P51587 BRCA2 DNA repair associated Nucleic acid binding 656 0.379 0.846 2.4E-25 0.100 None 1.000 12 0 1988 2019
Entrez Id: 2177
Gene Symbol: FANCD2
FANCD2
Q9BXW9 FA complementation group D2 272 0.479 0.885 1.1E-30 0.100 None 1.000 11 0 1988 2019
Entrez Id: 7031
Gene Symbol: TFF1
TFF1
P04155 trefoil factor 1 Signaling 147 0.529 0.769 8.9E-04 0.080 None 0.875 8 0 1995 2006
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
P35222 catenin beta 1 1368 0.303 0.885 1.00 0.080 None 1.000 8 0 1999 2008
Entrez Id: 338412
Gene Symbol: TAS2R64P
TAS2R64P
taste 2 receptor member 64 pseudogene 33 0.678 0.385 0.080 None 0.875 8 0 1995 2006
Entrez Id: 1636
Gene Symbol: ACE
ACE
P12821 angiotensin I converting enzyme Enzyme 1082 0.328 0.923 1.0E-37 0.310 None 1.000 6 0 1999 2019
Entrez Id: 8803
Gene Symbol: SUCLA2
SUCLA2
Q9P2R7 succinate-CoA ligase ADP-forming subunit beta Enzyme 136 0.566 0.654 2.3E-03 0.060 None 0.833 6 0 1995 2019
Entrez Id: 6622
Gene Symbol: SNCA
SNCA
P37840 synuclein alpha Transporter 449 0.427 0.885 0.88 0.060 None 1.000 6 0 1998 2018
Entrez Id: 6653
Gene Symbol: SORL1
SORL1
Q92673 sortilin related receptor 1 Transporter 103 0.582 0.692 7.7E-11 0.340 None 1.000 5 0 2006 2018
Entrez Id: 23621
Gene Symbol: BACE1
BACE1
P56817 beta-secretase 1 Enzyme 120 0.559 0.769 0.88 0.330 None 1.000 4 0 2006 2019
Entrez Id: 836
Gene Symbol: CASP3
CASP3
P42574 caspase 3 Enzyme 819 0.351 0.923 0.10 0.330 None 1.000 4 0 2001 2008
Entrez Id: 5621
Gene Symbol: PRNP
PRNP
F7VJQ1 P04156 prion protein 426 0.445 0.923 6.3E-04 0.330 None 1.000 4 0 2000 2013
Entrez Id: 1509
Gene Symbol: CTSD
CTSD
P07339 cathepsin D Enzyme 242 0.478 0.846 9.2E-04 0.040 None 1.000 4 0 1994 2014
Entrez Id: 54209
Gene Symbol: TREM2
TREM2
Q9NZC2 triggering receptor expressed on myeloid cells 2 239 0.519 0.769 3.3E-09 0.510 None 1.000 4 0 2013 2017
Entrez Id: 4550
Gene Symbol: RNR2
RNR2
Q8IVG9 l-rRNA 76 0.603 0.692 0.040 None 1.000 4 0 2001 2015
Entrez Id: 2
Gene Symbol: A2M
A2M
P01023 alpha-2-macroglobulin Enzyme modulator 147 0.529 0.769 4.5E-11 0.310 None 1.000 4 0 1998 2016
Entrez Id: 23607
Gene Symbol: CD2AP
CD2AP
Q9Y5K6 CD2 associated protein 113 0.558 0.731 0.23 0.300 None 1.000 3 0 2011 2018
Entrez Id: 338399
Gene Symbol: TAS2R62P
TAS2R62P
taste 2 receptor member 62 pseudogene 15 0.729 0.192 0.030 None 1.000 3 0 1995 2017
Entrez Id: 4747
Gene Symbol: NEFL
NEFL
P07196 neurofilament light 247 0.488 0.769 0.030 None 1.000 3 0 2017 2019
Entrez Id: 6647
Gene Symbol: SOD1
SOD1
P00441 superoxide dismutase 1 Enzyme 689 0.379 0.962 0.18 0.030 None 1.000 3 0 1995 2002
Entrez Id: 5819
Gene Symbol: NECTIN2
NECTIN2
Q92692 nectin cell adhesion molecule 2 106 0.575 0.769 0.97 0.300 None 1.000 3 0 2018 2018
Entrez Id: 10347
Gene Symbol: ABCA7
ABCA7
Q8IZY2 ATP binding cassette subfamily A member 7 Transporter 70 0.644 0.577 2.1E-55 0.500 None 1.000 3 0 2011 2016
Entrez Id: 1191
Gene Symbol: CLU
CLU
P10909 clusterin 412 0.426 0.885 7.8E-05 0.300 None 1.000 3 0 2009 2011
Entrez Id: 80308
Gene Symbol: FLAD1
FLAD1
Q8NFF5 flavin adenine dinucleotide synthetase 1 58 0.638 0.692 9.4E-03 0.030 None 1.000 3 0 1994 2016
Entrez Id: 5468
Gene Symbol: PPARG
PPARG
P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 877 0.358 0.885 2.9E-02 0.300 None 1.000 3 0 2005 2018