Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR 		P42898 methylenetetrahydrofolate reductase 985 0.337 0.885 3.2E-10 0.040 None 0.750 4 3 2006 2017
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2 		P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1234 0.314 0.962 1.00 0.030 None 1.000 3 0 2007 2014
Entrez Id: 5594
Gene Symbol: MAPK1
MAPK1 		P28482 mitogen-activated protein kinase 1 Kinase 1059 0.330 0.923 1.00 0.030 None 1.000 3 0 2002 2018
Entrez Id: 472
Gene Symbol: ATM
ATM 		Q13315 ATM serine/threonine kinase Kinase 684 0.374 0.885 5.6E-47 0.030 None 1.000 3 0 2007 2018
Entrez Id: 4221
Gene Symbol: MEN1
MEN1 		O00255 menin 1 364 0.444 0.808 1.00 0.030 None 1.000 3 0 2005 2017
Entrez Id: 5595
Gene Symbol: MAPK3
MAPK3 		P27361 mitogen-activated protein kinase 3 Kinase 647 0.379 0.885 3.7E-02 0.030 None 1.000 3 0 2002 2008
Entrez Id: 7076
Gene Symbol: TIMP1
TIMP1 		P01033 TIMP metallopeptidase inhibitor 1 Enzyme modulator 603 0.380 0.885 0.50 0.030 None 1.000 3 0 2003 2018
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		P00533 epidermal growth factor receptor Kinase 1394 0.295 0.885 0.37 0.030 None 0.667 3 0 2009 2014
Entrez Id: 57007
Gene Symbol: ACKR3
ACKR3 		P25106 atypical chemokine receptor 3 G-protein coupled receptor 400 0.428 0.885 0.39 0.030 None 1.000 3 0 2011 2014
Entrez Id: 5155
Gene Symbol: PDGFB
PDGFB 		P01127 platelet derived growth factor subunit B Signaling 301 0.488 0.846 0.77 0.030 None 1.000 3 0 1990 1993
Entrez Id: 1950
Gene Symbol: EGF
EGF 		P01133 epidermal growth factor 774 0.357 0.923 8.5E-17 0.030 None 1.000 3 0 1991 1996
Entrez Id: 841
Gene Symbol: CASP8
CASP8 		Q14790 caspase 8 Enzyme 480 0.404 0.923 3.7E-06 0.030 None 0.667 3 1 2007 2016
Entrez Id: 4552
Gene Symbol: MTRR
MTRR 		Q9UBK8 5-methyltetrahydrofolate-homocysteine methyltransferase reductase 207 0.502 0.808 2.2E-14 0.030 None 1.000 3 1 2008 2017
Entrez Id: 7077
Gene Symbol: TIMP2
TIMP2 		P16035 TIMP metallopeptidase inhibitor 2 Enzyme modulator 404 0.425 0.846 0.79 0.030 None 1.000 3 0 2003 2018
Entrez Id: 5795
Gene Symbol: PTPRJ
PTPRJ 		Q12913 protein tyrosine phosphatase receptor type J Enzyme 79 0.606 0.615 1.3E-11 0.030 None 1.000 3 0 2011 2020
Entrez Id: 57447
Gene Symbol: NDRG2
NDRG2 		Q9UN36 NDRG family member 2 Enzyme 156 0.518 0.692 2.2E-05 0.030 None 1.000 3 0 2005 2019
Entrez Id: 4313
Gene Symbol: MMP2
MMP2 		P08253 matrix metallopeptidase 2 Enzyme 1021 0.333 0.923 0.84 0.030 None 1.000 3 0 2003 2016
Entrez Id: 2120
Gene Symbol: ETV6
ETV6 		P41212 ETS variant transcription factor 6 Transcription factor 241 0.477 0.731 0.97 0.020 None 1.000 2 0 2005 2012
Entrez Id: 7321
Gene Symbol: UBE2D1
UBE2D1 		P51668 ubiquitin conjugating enzyme E2 D1 Enzyme 27 0.700 0.385 0.12 0.020 None 1.000 2 0 2019 2020
Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1 		P09211 glutathione S-transferase pi 1 610 0.383 0.923 1.4E-02 0.020 None 0.500 2 0 2005 2012
Entrez Id: 1974
Gene Symbol: EIF4A2
EIF4A2 		Q14240 eukaryotic translation initiation factor 4A2 74 0.604 0.731 1.00 0.020 None 1.000 2 0 2018 2018
Entrez Id: 7153
Gene Symbol: TOP2A
TOP2A 		P11388 DNA topoisomerase II alpha 200 0.497 0.731 0.99 0.020 None 1.000 2 0 2017 2018
Entrez Id: 2048
Gene Symbol: EPHB2
EPHB2 		P29323 EPH receptor B2 Kinase 649 0.374 0.846 1.00 0.020 None 1.000 2 0 2017 2018
Entrez Id: 3953
Gene Symbol: LEPR
LEPR 		P48357 leptin receptor Signaling 416 0.433 0.808 0.99 0.020 None 1.000 2 0 2011 2018
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		P04626 erb-b2 receptor tyrosine kinase 2 Kinase 995 0.328 0.923 6.0E-03 0.020 None 1.000 2 0 2010 2015