Source: BEFREE ×
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 1021
Gene Symbol: CDK6
CDK6 		Q00534 cyclin dependent kinase 6 Kinase 199 0.471 0.731 0.98 0.310 None 1.000 1 0 2017 2017
Entrez Id: 6794
Gene Symbol: STK11
STK11 		Q15831 serine/threonine kinase 11 Kinase 303 0.435 0.808 0.99 0.310 None 1.000 1 0 2012 2012
Entrez Id: 4293
Gene Symbol: MAP3K9
MAP3K9 		P80192 mitogen-activated protein kinase kinase kinase 9 Kinase 20 0.711 0.269 0.12 0.310 None 1.000 1 0 2011 2011
Entrez Id: 2043
Gene Symbol: EPHA4
EPHA4 		P54764 EPH receptor A4 Kinase 89 0.566 0.846 1.00 0.310 None 1.000 1 0 1997 1997
Entrez Id: 5587
Gene Symbol: PRKD1
PRKD1 		Q15139 protein kinase D1 Kinase 125 0.531 0.846 6.6E-07 0.310 None 1.000 1 0 2017 2017
Entrez Id: 673
Gene Symbol: BRAF
BRAF 		P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 888 0.319 0.846 1.00 0.100 None 0.992 400 8 2003 2020
Entrez Id: 5609
Gene Symbol: MAP2K7
MAP2K7 		O14733 mitogen-activated protein kinase kinase 7 Kinase 394 0.419 0.808 1.00 0.100 None 0.986 71 1 2011 2020
Entrez Id: 1493
Gene Symbol: CTLA4
CTLA4 		P16410 cytotoxic T-lymphocyte associated protein 4 600 0.369 0.923 0.94 0.100 None 0.983 59 0 2005 2020
Entrez Id: 3558
Gene Symbol: IL2
IL2 		P60568 interleukin 2 894 0.336 0.885 0.48 0.100 None 0.978 46 0 1990 2019
Entrez Id: 29126
Gene Symbol: CD274
CD274 		Q9NZQ7 CD274 molecule Receptor 990 0.324 0.923 1.9E-02 0.100 None 0.972 36 0 2012 2019
Entrez Id: 5133
Gene Symbol: PDCD1
PDCD1 		Q15116 programmed cell death 1 477 0.402 0.846 0.42 0.100 None 1.000 31 0 2015 2019
Entrez Id: 4893
Gene Symbol: NRAS
NRAS 		P01111 NRAS proto-oncogene, GTPase Enzyme modulator 396 0.390 0.808 0.49 0.100 None 1.000 23 5 2007 2019
Entrez Id: 2315
Gene Symbol: MLANA
MLANA 		Q16655 melan-A 84 0.579 0.692 1.3E-09 0.100 None 1.000 20 0 1998 2019
Entrez Id: 7299
Gene Symbol: TYR
TYR 		P14679 tyrosinase Enzyme 213 0.473 0.808 5.0E-32 0.100 None 1.000 19 0 1994 2018
Entrez Id: 3815
Gene Symbol: KIT
KIT 		P10721 KIT proto-oncogene, receptor tyrosine kinase Kinase 627 0.366 0.808 0.98 0.100 None 1.000 18 1 2006 2019
Entrez Id: 388015
Gene Symbol: RTL1
RTL1 		A6NKG5 retrotransposon Gag like 1 117 0.554 0.808 5.6E-03 0.100 None 1.000 14 0 1994 2018
Entrez Id: 22882
Gene Symbol: ZHX2
ZHX2 		Q9Y6X8 zinc fingers and homeoboxes 2 Transcription factor 169 0.510 0.654 3.4E-02 0.100 None 1.000 11 0 2011 2017
Entrez Id: 5894
Gene Symbol: RAF1
RAF1 		P04049 Raf-1 proto-oncogene, serine/threonine kinase Kinase 308 0.418 0.885 0.85 0.100 None 1.000 11 1 2011 2017
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A 		P42771 Q8N726 cyclin dependent kinase inhibitor 2A 1214 0.300 0.885 0.39 0.100 None 1.000 10 1 2001 2019
Entrez Id: 6490
Gene Symbol: PMEL
PMEL 		P40967 premelanosome protein Signaling 135 0.531 0.769 3.1E-18 0.100 None 1.000 10 0 1998 2019
Entrez Id: 23583
Gene Symbol: SMUG1
SMUG1 		Q53HV7 single-strand-selective monofunctional uracil-DNA glycosylase 1 1029 0.322 0.923 4.5E-04 0.090 None 0.889 9 0 2018 2019
Entrez Id: 6285
Gene Symbol: S100B
S100B 		P04271 S100 calcium binding protein B Calcium-binding protein 544 0.383 0.923 4.4E-02 0.080 None 1.000 8 0 2005 2019
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG 		P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1087 0.320 0.885 1.4E-06 0.080 None 1.000 8 0 2008 2019
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1 		P35222 catenin beta 1 1156 0.303 0.885 1.00 0.080 None 0.875 8 0 2002 2019
Entrez Id: 5291
Gene Symbol: PIK3CB
PIK3CB 		P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1077 0.322 0.885 1.00 0.080 None 1.000 8 0 2008 2019