Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3119
Gene Symbol: HLA-DQB1
HLA-DQB1
P01920 major histocompatibility complex, class II, DQ beta 1 Immune response 356 0.407 0.885 8.9E-03 0.010 None < 0.001 1 0 1996 1996
Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1
P09488 glutathione S-transferase mu 1 581 0.380 0.923 2.1E-03 0.010 None < 0.001 1 0 2000 2000
Entrez Id: 3172
Gene Symbol: HNF4A
HNF4A
P41235 hepatocyte nuclear factor 4 alpha Nuclear receptor 241 0.461 0.808 0.15 0.010 None < 0.001 1 0 2019 2019
Entrez Id: 406991
Gene Symbol: MIR21
MIR21
microRNA 21 705 0.363 0.846 0.040 None 0.750 4 0 2009 2018
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
P15692 vascular endothelial growth factor A Signaling 1737 0.266 0.923 2.4E-05 0.100 None 0.923 13 0 2001 2017
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
P01116 KRAS proto-oncogene, GTPase Enzyme modulator 805 0.320 0.923 7.9E-04 0.200 None 1.000 27 1 1991 2019
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2245 0.236 0.962 0.53 0.200 None 1.000 21 1 1993 2019
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
P42771 Q8N726 cyclin dependent kinase inhibitor 2A 1214 0.300 0.885 0.39 0.200 None 1.000 16 1 1994 2017
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
P51587 BRCA2 DNA repair associated Nucleic acid binding 459 0.379 0.846 2.4E-25 0.200 None 1.000 15 0 1996 2019
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
P38398 BRCA1 DNA repair associated Enzyme 576 0.367 0.923 9.2E-29 0.200 None 1.000 12 0 1996 2019
Entrez Id: 4089
Gene Symbol: SMAD4
SMAD4
Q13485 SMAD family member 4 Transcription factor 377 0.401 0.808 1.00 0.200 None 1.000 11 0 2000 2016
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
P00533 epidermal growth factor receptor Kinase 1308 0.295 0.885 0.37 0.070 None 1.000 7 0 2003 2019
Entrez Id: 3159
Gene Symbol: HMGA1
HMGA1
P17096 high mobility group AT-hook 1 Nucleic acid binding 193 0.494 0.769 0.83 0.060 None 1.000 6 0 2006 2013
Entrez Id: 10232
Gene Symbol: MSLN
MSLN
Q13421 mesothelin Extracellular structure 130 0.525 0.692 5.9E-25 0.060 None 1.000 6 0 2001 2020
Entrez Id: 4585
Gene Symbol: MUC4
MUC4
Q99102 mucin 4, cell surface associated 155 0.506 0.769 2.8E-54 0.060 None 1.000 6 0 2001 2013
Entrez Id: 115482713
Gene Symbol: H3P10
H3P10
H3 histone pseudogene 10 769 0.350 0.846 0.050 None 1.000 5 0 2001 2014
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
P04626 erb-b2 receptor tyrosine kinase 2 Kinase 942 0.328 0.923 6.0E-03 0.150 None 1.000 5 0 1995 2016
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 953 0.327 0.923 0.98 0.050 None 1.000 5 0 2007 2018
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1043 0.314 0.962 1.00 0.050 None 1.000 5 0 1999 2019
Entrez Id: 1080
Gene Symbol: CFTR
CFTR
P13569 CF transmembrane conductance regulator Ion channel 365 0.424 0.885 2.2E-58 0.050 None 1.000 5 0 1998 2014
Entrez Id: 94025
Gene Symbol: MUC16
MUC16
Q8WXI7 mucin 16, cell surface associated 228 0.479 0.808 8.3E-112 0.050 None 1.000 5 0 2013 2018
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
P10145 C-X-C motif chemokine ligand 8 Signaling 1173 0.310 0.962 2.7E-04 0.050 None 1.000 5 0 2000 2008
Entrez Id: 23583
Gene Symbol: SMUG1
SMUG1
Q53HV7 single-strand-selective monofunctional uracil-DNA glycosylase 1 1029 0.322 0.923 4.5E-04 0.050 None 1.000 5 0 2017 2019
Entrez Id: 5979
Gene Symbol: RET
RET
P07949 ret proto-oncogene Kinase 453 0.392 0.885 1.00 0.040 None 1.000 4 0 2015 2019
Entrez Id: 4582
Gene Symbol: MUC1
MUC1
P15941 mucin 1, cell surface associated 552 0.384 0.885 1.9E-02 0.040 None 1.000 4 0 1993 2008