Source: BEFREE ×
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		P01116 KRAS proto-oncogene, GTPase Enzyme modulator 805 0.320 0.923 7.9E-04 0.200 None 1.000 27 1 1991 2019
Entrez Id: 7157
Gene Symbol: TP53
TP53 		P04637 tumor protein p53 Transcription factor 2245 0.236 0.962 0.53 0.200 None 1.000 21 1 1993 2019
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A 		P42771 Q8N726 cyclin dependent kinase inhibitor 2A 1214 0.300 0.885 0.39 0.200 None 1.000 16 1 1994 2017
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2 		P51587 BRCA2 DNA repair associated Nucleic acid binding 459 0.379 0.846 2.4E-25 0.200 None 1.000 15 0 1996 2019
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1 		P38398 BRCA1 DNA repair associated Enzyme 576 0.367 0.923 9.2E-29 0.200 None 1.000 12 0 1996 2019
Entrez Id: 4089
Gene Symbol: SMAD4
SMAD4 		Q13485 SMAD family member 4 Transcription factor 377 0.401 0.808 1.00 0.200 None 1.000 11 0 2000 2016
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		P04626 erb-b2 receptor tyrosine kinase 2 Kinase 942 0.328 0.923 6.0E-03 0.150 None 1.000 5 0 1995 2016
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA 		P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1277 0.292 0.923 1.00 0.130 None 1.000 3 0 2007 2016
Entrez Id: 3265
Gene Symbol: HRAS
HRAS 		P01112 HRas proto-oncogene, GTPase Enzyme modulator 457 0.378 0.885 8.0E-02 0.120 None 1.000 2 0 1994 2016
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1 		P35222 catenin beta 1 1156 0.303 0.885 1.00 0.120 None 1.000 2 0 2014 2016
Entrez Id: 79728
Gene Symbol: PALB2
PALB2 		Q86YC2 partner and localizer of BRCA2 87 0.485 0.769 3.0E-19 0.120 None 1.000 2 0 2012 2018
Entrez Id: 7048
Gene Symbol: TGFBR2
TGFBR2 		P37173 transforming growth factor beta receptor 2 Kinase 307 0.413 0.846 0.13 0.110 None 1.000 1 0 1998 1998
Entrez Id: 6794
Gene Symbol: STK11
STK11 		Q15831 serine/threonine kinase 11 Kinase 303 0.435 0.808 0.99 0.110 None 1.000 1 0 2001 2001
Entrez Id: 54894
Gene Symbol: RNF43
RNF43 		Q68DV7 ring finger protein 43 56 0.584 0.577 0.73 0.110 None 1.000 1 0 2013 2013
Entrez Id: 4072
Gene Symbol: EPCAM
EPCAM 		P16422 epithelial cell adhesion molecule 259 0.451 0.885 1.3E-07 0.110 None 1.000 1 0 2011 2011
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		P15692 vascular endothelial growth factor A Signaling 1737 0.266 0.923 2.4E-05 0.100 None 0.923 13 0 2001 2017
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		P00533 epidermal growth factor receptor Kinase 1308 0.295 0.885 0.37 0.070 None 1.000 7 0 2003 2019
Entrez Id: 4585
Gene Symbol: MUC4
MUC4 		Q99102 mucin 4, cell surface associated 155 0.506 0.769 2.8E-54 0.060 None 1.000 6 0 2001 2013
Entrez Id: 10232
Gene Symbol: MSLN
MSLN 		Q13421 mesothelin Extracellular structure 130 0.525 0.692 5.9E-25 0.060 None 1.000 6 0 2001 2020
Entrez Id: 3159
Gene Symbol: HMGA1
HMGA1 		P17096 high mobility group AT-hook 1 Nucleic acid binding 193 0.494 0.769 0.83 0.060 None 1.000 6 0 2006 2013
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A 		Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 953 0.327 0.923 0.98 0.050 None 1.000 5 0 2007 2018
Entrez Id: 115482713
Gene Symbol: H3P10
H3P10 		H3 histone pseudogene 10 769 0.350 0.846 0.050 None 1.000 5 0 2001 2014
Entrez Id: 94025
Gene Symbol: MUC16
MUC16 		Q8WXI7 mucin 16, cell surface associated 228 0.479 0.808 8.3E-112 0.050 None 1.000 5 0 2013 2018
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2 		P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1043 0.314 0.962 1.00 0.050 None 1.000 5 0 1999 2019
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8 		P10145 C-X-C motif chemokine ligand 8 Signaling 1173 0.310 0.962 2.7E-04 0.050 None 1.000 5 0 2000 2008