Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 472
Gene Symbol: ATM
ATM 		Q13315 ATM serine/threonine kinase Kinase 684 0.374 0.885 5.6E-47 0.400 definitive 1.000 22 2 1998 2019
Entrez Id: 999
Gene Symbol: CDH1
CDH1 		P12830 cadherin 1 508 0.401 0.808 0.15 0.310 definitive 1.000 13 0 1991 2018
Entrez Id: 84464
Gene Symbol: SLX4
SLX4 		Q8IY92 SLX4 structure-specific endonuclease subunit 123 0.565 0.731 1.6E-22 0.330 limited 1.000 10 0 2011 2017
Entrez Id: 5892
Gene Symbol: RAD51D
RAD51D 		O75771 RAD51 paralog D 36 0.674 0.385 1.1E-09 0.510 limited 1.000 9 1 2000 2019
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C 		O43502 RAD51 paralog C 162 0.533 0.692 6.2E-14 0.320 disputed 1.000 9 1 2010 2019
Entrez Id: 4292
Gene Symbol: MLH1
MLH1 		P40692 mutL homolog 1 Nucleic acid binding 526 0.399 0.808 3.4E-05 0.320 disputed 1.000 8 0 2000 2017
Entrez Id: 7516
Gene Symbol: XRCC2
XRCC2 		O43543 X-ray repair cross complementing 2 187 0.512 0.731 4.0E-07 0.530 limited 1.000 7 1 1999 2019
Entrez Id: 4361
Gene Symbol: MRE11
MRE11 		P49959 MRE11 homolog, double strand break repair nuclease 171 0.527 0.808 1.3E-12 0.320 disputed 1.000 7 1 1998 2017
Entrez Id: 79648
Gene Symbol: MCPH1
MCPH1 		Q8NEM0 microcephalin 1 Nucleic acid binding 141 0.540 0.846 7.8E-30 0.310 limited 1.000 7 0 2005 2016
Entrez Id: 60500
Gene Symbol: BRCA3
BRCA3 		breast cancer 3 27 0.705 0.269 0.060 None 1.000 6 0 2007 2017
Entrez Id: 5965
Gene Symbol: RECQL
RECQL 		P46063 RecQ like helicase Enzyme 58 0.615 0.615 1.5E-20 0.320 moderate 1.000 6 0 2005 2019
Entrez Id: 348654
Gene Symbol: GEN1
GEN1 		Q17RS7 GEN1 Holliday junction 5' flap endonuclease 35 0.682 0.500 3.7E-15 0.300 disputed 1.000 6 0 2011 2016
Entrez Id: 57697
Gene Symbol: FANCM
FANCM 		Q8IYD8 FA complementation group M Enzyme 147 0.543 0.731 2.4E-15 0.050 None 1.000 5 1 2009 2019
Entrez Id: 142
Gene Symbol: PARP1
PARP1 		P09874 poly(ADP-ribose) polymerase 1 565 0.389 0.923 3.3E-04 0.050 None 1.000 5 0 2012 2015
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		P52701 mutS homolog 6 Nucleic acid binding 296 0.462 0.731 3.7E-05 0.310 disputed 1.000 5 1 2002 2018
Entrez Id: 60561
Gene Symbol: RINT1
RINT1 		Q6NUQ1 RAD50 interactor 1 19 0.743 0.231 5.3E-13 0.300 disputed 1.000 5 0 2001 2016
Entrez Id: 1302
Gene Symbol: COL11A2
COL11A2 		P13942 collagen type XI alpha 2 chain 399 0.435 0.846 0.70 0.040 None 1.000 4 0 2012 2015
Entrez Id: 115761
Gene Symbol: ARL11
ARL11 		Q969Q4 ADP ribosylation factor like GTPase 11 35 0.670 0.423 5.3E-03 0.040 None 1.000 4 4 2006 2011
Entrez Id: 5395
Gene Symbol: PMS2
PMS2 		P54278 PMS1 homolog 2, mismatch repair system component Nucleic acid binding 244 0.484 0.808 4.5E-27 0.300 disputed 1.000 4 0 1995 2018
Entrez Id: 3294
Gene Symbol: HSD17B2
HSD17B2 		P37059 hydroxysteroid 17-beta dehydrogenase 2 Enzyme 42 0.656 0.385 1.8E-10 0.030 None 1.000 3 0 1994 2007
Entrez Id: 3479
Gene Symbol: IGF1
IGF1 		P05019 insulin like growth factor 1 1206 0.318 0.885 0.27 0.030 None 1.000 3 0 2005 2008
Entrez Id: 4436
Gene Symbol: MSH2
MSH2 		P43246 mutS homolog 2 Nucleic acid binding 490 0.406 0.808 0.90 0.310 disputed 1.000 3 0 2003 2017
Entrez Id: 6794
Gene Symbol: STK11
STK11 		Q15831 serine/threonine kinase 11 Kinase 372 0.435 0.808 0.99 0.030 None 1.000 3 0 2000 2015
Entrez Id: 5245
Gene Symbol: PHB
PHB 		P35232 prohibitin 177 0.511 0.846 0.76 0.030 None 1.000 3 0 1992 2008
Entrez Id: 7251
Gene Symbol: TSG101
TSG101 		Q99816 tumor susceptibility 101 Enzyme 80 0.588 0.615 0.34 0.030 None 1.000 3 0 1998 2002