Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 5179
Gene Symbol: PENK
PENK
P01210 proenkephalin Signaling 124 0.560 0.808 2.1E-04 0.320 None 0.500 2 0 1999 2007
Entrez Id: 735
Gene Symbol: C9
C9
P02748 complement C9 62 0.619 0.692 1.6E-24 0.300 None 1.000 1 0 2008 2008
Entrez Id: 168667
Gene Symbol: BMPER
BMPER
Q8N8U9 BMP binding endothelial regulator Enzyme modulator 75 0.641 0.577 6.6E-07 0.300 None 1.000 1 0 2008 2008
Entrez Id: 23508
Gene Symbol: TTC9
TTC9
Q92623 tetratricopeptide repeat domain 9 Enzyme 6 0.839 0.077 6.8E-02 0.300 None 1.000 1 0 2008 2008
Entrez Id: 89795
Gene Symbol: NAV3
NAV3
Q8IVL0 neuron navigator 3 46 0.653 0.615 1.00 0.300 None 1.000 1 0 2008 2008
Entrez Id: 1066
Gene Symbol: CES1
CES1
P23141 carboxylesterase 1 Enzyme 80 0.590 0.692 3.3E-15 0.300 None 1.000 1 0 2003 2003
Entrez Id: 4988
Gene Symbol: OPRM1
OPRM1
P35372 opioid receptor mu 1 G-protein coupled receptor 370 0.457 0.808 7.9E-11 0.100 None 0.867 30 2 1998 2019
Entrez Id: 4985
Gene Symbol: OPRD1
OPRD1
P41143 opioid receptor delta 1 G-protein coupled receptor 92 0.604 0.731 3.3E-03 0.100 None 0.900 10 4 2000 2019
Entrez Id: 147929
Gene Symbol: ZNF565
ZNF565
Q8N9K5 zinc finger protein 565 4 0.931 0.077 1.0E-05 0.100 None 1.000 1 1 2017 2017
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
P14416 dopamine receptor D2 G-protein coupled receptor 437 0.436 0.846 0.75 0.090 None 1.000 9 3 2000 2016
Entrez Id: 5173
Gene Symbol: PDYN
PDYN
P01213 prodynorphin Signaling 197 0.535 0.577 1.7E-04 0.050 None 0.800 5 3 2005 2019
Entrez Id: 4986
Gene Symbol: OPRK1
OPRK1
P41145 opioid receptor kappa 1 G-protein coupled receptor 156 0.555 0.615 4.1E-05 0.050 None 0.800 5 5 2004 2019
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
P08183 ATP binding cassette subfamily B member 1 Transporter 933 0.344 0.885 1.3E-05 0.050 None 0.800 5 1 2006 2017
Entrez Id: 1312
Gene Symbol: COMT
COMT
P21964 catechol-O-methyltransferase Enzyme 622 0.400 0.923 1.1E-06 0.040 None 1.000 4 2 2008 2016
Entrez Id: 5443
Gene Symbol: POMC
POMC
P01189 proopiomelanocortin 873 0.356 0.846 1.2E-04 0.030 None 0.667 3 0 1998 2011
Entrez Id: 1815
Gene Symbol: DRD4
DRD4
P21917 dopamine receptor D4 G-protein coupled receptor 189 0.517 0.577 9.3E-09 0.030 None 0.667 3 0 2000 2011
Entrez Id: 27185
Gene Symbol: DISC1
DISC1
Q9NRI5 DISC1 scaffold protein 136 0.548 0.769 1.7E-06 0.030 None 1.000 3 2 2014 2016
Entrez Id: 3060
Gene Symbol: HCRT
HCRT
O43612 hypocretin neuropeptide precursor 237 0.500 0.808 2.9E-02 0.020 None 1.000 2 0 2018 2019
Entrez Id: 2903
Gene Symbol: GRIN2A
GRIN2A
Q12879 glutamate ionotropic receptor NMDA type subunit 2A Ion channel 212 0.522 0.808 1.00 0.020 None 1.000 2 0 2013 2018
Entrez Id: 6531
Gene Symbol: SLC6A3
SLC6A3
Q01959 solute carrier family 6 member 3 Transporter 373 0.453 0.885 1.00 0.020 None 1.000 2 0 2016 2017
Entrez Id: 51083
Gene Symbol: GAL
GAL
P22466 galanin and GMAP prepropeptide 226 0.493 0.846 4.4E-06 0.020 None 1.000 2 1 2005 2013
Entrez Id: 57486
Gene Symbol: NLN
NLN
Q9BYT8 neurolysin Enzyme 74 0.597 0.731 3.9E-12 0.020 None 1.000 2 0 2005 2019
Entrez Id: 4987
Gene Symbol: OPRL1
OPRL1
P41146 opioid related nociceptin receptor 1 G-protein coupled receptor 76 0.628 0.462 0.48 0.020 None 1.000 2 2 2008 2010
Entrez Id: 255239
Gene Symbol: ANKK1
ANKK1
Q8NFD2 ankyrin repeat and kinase domain containing 1 Kinase 71 0.604 0.462 7.4E-12 0.020 None 1.000 2 1 2009 2015
Entrez Id: 1565
Gene Symbol: CYP2D6
CYP2D6
P10635 cytochrome P450 family 2 subfamily D member 6 432 0.437 0.885 1.1E-25 0.020 None 1.000 2 0 1997 2008