Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7157
Gene Symbol: TP53
TP53 		P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.500 None 0.973 219 86 1991 2020
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA 		P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1511 0.292 0.923 1.00 0.500 None 1.000 68 29 2001 2020
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		P00533 epidermal growth factor receptor Kinase 1394 0.295 0.885 0.37 0.500 None 0.982 277 18 1992 2020
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A 		P42771 Q8N726 cyclin dependent kinase inhibitor 2A 1314 0.300 0.885 0.39 0.500 None 0.983 115 9 1994 2019
Entrez Id: 55294
Gene Symbol: FBXW7
FBXW7 		Q969H0 F-box and WD repeat domain containing 7 Enzyme modulator 257 0.465 0.808 1.00 0.120 None 1.000 3 7 2016 2019
Entrez Id: 3265
Gene Symbol: HRAS
HRAS 		P01112 HRas proto-oncogene, GTPase Enzyme modulator 698 0.378 0.885 8.0E-02 0.150 None 1.000 6 6 1990 2018
Entrez Id: 1870
Gene Symbol: E2F2
E2F2 		Q14209 E2F transcription factor 2 Nucleic acid binding 75 0.599 0.692 0.26 0.010 None 1.000 1 6 2012 2012
Entrez Id: 2068
Gene Symbol: ERCC2
ERCC2 		P18074 ERCC excision repair 2, TFIIH core complex helicase subunit Enzyme 499 0.420 0.846 7.1E-20 0.080 None 0.875 8 5 2000 2017
Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2 		Q16236 nuclear factor, erythroid 2 like 2 Enzyme 823 0.357 0.885 3.6E-03 0.440 None 1.000 5 5 2013 2019
Entrez Id: 4548
Gene Symbol: MTR
MTR 		Q99707 5-methyltetrahydrofolate-homocysteine methyltransferase 245 0.482 0.808 2.4E-12 0.040 None 1.000 4 4 2005 2012
Entrez Id: 673
Gene Symbol: BRAF
BRAF 		P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1228 0.319 0.846 1.00 0.130 None 0.750 4 4 2003 2016
Entrez Id: 11332
Gene Symbol: ACOT7
ACOT7 		O00154 acyl-CoA thioesterase 7 Enzyme 146 0.531 0.769 0.76 0.010 None 1.000 1 4 1998 1998
Entrez Id: 7127
Gene Symbol: TNFAIP2
TNFAIP2 		Q03169 TNF alpha induced protein 2 Transporter 25 0.711 0.423 8.3E-05 0.010 None 1.000 1 4 2011 2011
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2 		P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1234 0.314 0.962 1.00 0.400 None 0.966 29 3 1999 2019
Entrez Id: 5728
Gene Symbol: PTEN
PTEN 		P60484 phosphatase and tensin homolog Enzyme 1349 0.305 0.923 0.26 0.800 strong 0.952 21 3 1972 2019
Entrez Id: 7515
Gene Symbol: XRCC1
XRCC1 		P18887 X-ray repair cross complementing 1 410 0.421 0.923 6.3E-09 0.100 None 0.905 21 3 1992 2020
Entrez Id: 7517
Gene Symbol: XRCC3
XRCC3 		O43542 X-ray repair cross complementing 3 184 0.505 0.769 1.9E-10 0.090 None 0.889 9 3 2002 2016
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR 		P42898 methylenetetrahydrofolate reductase 985 0.337 0.885 3.2E-10 0.060 None 1.000 6 3 2005 2012
Entrez Id: 1869
Gene Symbol: E2F1
E2F1 		Q01094 E2F transcription factor 1 Nucleic acid binding 324 0.441 0.846 0.99 0.050 None 1.000 5 3 1998 2012
Entrez Id: 2072
Gene Symbol: ERCC4
ERCC4 		Q92889 ERCC excision repair 4, endonuclease catalytic subunit Enzyme 325 0.468 0.846 1.4E-12 0.050 None 1.000 5 3 2011 2019
Entrez Id: 3621
Gene Symbol: ING1
ING1 		Q9UK53 inhibitor of growth family member 1 Nucleic acid binding 99 0.573 0.692 9.7E-03 0.710 None 1.000 2 3 2000 2000
Entrez Id: 4552
Gene Symbol: MTRR
MTRR 		Q9UBK8 5-methyltetrahydrofolate-homocysteine methyltransferase reductase 207 0.502 0.808 2.2E-14 0.020 None 1.000 2 3 2005 2007
Entrez Id: 7421
Gene Symbol: VDR
VDR 		P11473 vitamin D receptor Nuclear receptor 852 0.352 0.885 1.7E-05 0.020 None 1.000 2 3 2005 2011
Entrez Id: 3815
Gene Symbol: KIT
KIT 		P10721 KIT proto-oncogene, receptor tyrosine kinase Kinase 715 0.366 0.808 0.98 0.010 None 1.000 1 3 2017 2017
Entrez Id: 567
Gene Symbol: B2M
B2M 		P61769 beta-2-microglobulin Immune response 352 0.447 0.846 0.56 0.100 None 1.000 1 3 2016 2016