Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 2004
Gene Symbol: ELK3
ELK3
P41970 ETS transcription factor ELK3 Transcription factor 220 0.490 0.846 8.4E-02 0.010 None 1.000 1 0 2017 2017
Entrez Id: 6530
Gene Symbol: SLC6A2
SLC6A2
P23975 solute carrier family 6 member 2 Transporter 238 0.490 0.846 8.2E-02 0.010 None 1.000 1 0 2017 2017
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
Q86YC2 partner and localizer of BRCA2 260 0.485 0.769 3.0E-19 0.340 limited 1.000 11 0 2013 2019
Entrez Id: 5395
Gene Symbol: PMS2
PMS2
P54278 PMS1 homolog 2, mismatch repair system component Nucleic acid binding 244 0.484 0.808 4.5E-27 0.800 definitive 0.979 191 81 1994 2020
Entrez Id: 94025
Gene Symbol: MUC16
MUC16
Q8WXI7 mucin 16, cell surface associated 236 0.479 0.808 8.3E-112 0.010 None 1.000 1 0 2003 2003
Entrez Id: 3066
Gene Symbol: HDAC2
HDAC2
Q92769 histone deacetylase 2 Epigenetic regulator 257 0.476 0.846 1.00 0.020 None 1.000 2 0 2006 2008
Entrez Id: 4437
Gene Symbol: MSH3
MSH3
P20585 mutS homolog 3 Nucleic acid binding 245 0.474 0.769 7.4E-31 0.390 limited 0.857 14 0 1996 2018
Entrez Id: 2332
Gene Symbol: FMR1
FMR1
Q06787 FMRP translational regulator 1 Nucleic acid binding 346 0.473 0.769 0.65 0.010 None 1.000 1 0 1997 1997
Entrez Id: 1630
Gene Symbol: DCC
DCC
P43146 DCC netrin 1 receptor 279 0.471 0.808 0.99 0.010 None 1.000 1 0 1994 1994
Entrez Id: 407035
Gene Symbol: MIR31
MIR31
microRNA 31 235 0.471 0.769 0.010 None 1.000 1 0 2010 2010
Entrez Id: 404663
Gene Symbol: LINC01194
LINC01194
long intergenic non-protein coding RNA 1194 249 0.470 0.769 0.010 None 1.000 1 0 2001 2001
Entrez Id: 4092
Gene Symbol: SMAD7
SMAD7
O15105 SMAD family member 7 Transcription factor 269 0.470 0.769 0.55 0.010 None 1.000 1 0 2018 2018
Entrez Id: 27352
Gene Symbol: SGSM3
SGSM3
Q96HU1 small G protein signaling modulator 3 Enzyme 259 0.469 0.808 3.4E-15 0.010 None 1.000 1 0 2010 2010
Entrez Id: 4683
Gene Symbol: NBN
NBN
O60934 nibrin Nucleic acid binding 291 0.467 0.808 2.2E-16 0.010 None 1.000 1 0 2007 2007
Entrez Id: 4810
Gene Symbol: NHS
NHS
Q6T4R5 NHS actin remodeling regulator 295 0.466 0.846 1.00 0.030 None 1.000 3 0 2015 2019
Entrez Id: 2956
Gene Symbol: MSH6
MSH6
P52701 mutS homolog 6 Nucleic acid binding 296 0.462 0.731 3.7E-05 0.800 definitive 0.987 306 240 1988 2020
Entrez Id: 1586
Gene Symbol: CYP17A1
CYP17A1
P05093 cytochrome P450 family 17 subfamily A member 1 326 0.462 0.769 2.6E-04 0.010 None 1.000 1 0 2007 2007
Entrez Id: 11200
Gene Symbol: CHEK2
CHEK2
O96017 checkpoint kinase 2 Kinase 297 0.460 0.808 1.2E-24 0.330 limited 1.000 14 0 2003 2017
Entrez Id: 1045
Gene Symbol: CDX2
CDX2
Q99626 caudal type homeobox 2 Transcription factor 278 0.458 0.769 0.53 0.010 None 1.000 1 0 1999 1999
Entrez Id: 328
Gene Symbol: APEX1
APEX1
P27695 apurinic/apyrimidinic endodeoxyribonuclease 1 305 0.458 0.846 1.9E-07 0.010 None 1.000 1 0 2018 2018
Entrez Id: 1545
Gene Symbol: CYP1B1
CYP1B1
Q16678 cytochrome P450 family 1 subfamily B member 1 Enzyme 304 0.457 0.769 2.2E-05 0.010 None < 0.001 1 1 2018 2018
Entrez Id: 4087
Gene Symbol: SMAD2
SMAD2
Q15796 SMAD family member 2 Transcription factor 289 0.456 0.808 1.00 0.010 None 1.000 1 0 1999 1999
Entrez Id: 8289
Gene Symbol: ARID1A
ARID1A
O14497 AT-rich interaction domain 1A 341 0.455 0.846 1.00 0.020 None 1.000 2 0 2013 2014
Entrez Id: 1789
Gene Symbol: DNMT3B
DNMT3B
Q9UBC3 DNA methyltransferase 3 beta 315 0.453 0.846 0.20 0.010 None 1.000 1 0 2006 2006
Entrez Id: 4072
Gene Symbol: EPCAM
EPCAM
P16422 epithelial cell adhesion molecule 328 0.451 0.885 1.3E-07 0.700 None 1.000 36 1 2009 2019