Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3557
Gene Symbol: IL1RN
IL1RN
P18510 interleukin 1 receptor antagonist 701 0.373 0.923 3.1E-02 0.500 None 0 0
Entrez Id: 3659
Gene Symbol: IRF1
IRF1
P10914 interferon regulatory factor 1 Transcription factor 257 0.468 0.769 0.99 0.300 None 0 0
Entrez Id: 1316
Gene Symbol: KLF6
KLF6
Q99612 Kruppel like factor 6 Nucleic acid binding 204 0.501 0.846 0.98 0.300 None 0 0
Entrez Id: 843
Gene Symbol: CASP10
CASP10
Q92851 caspase 10 Enzyme 166 0.528 0.692 4.6E-12 0.300 None 0 0
Entrez Id: 999
Gene Symbol: CDH1
CDH1
P12830 cadherin 1 508 0.401 0.808 0.15 0.800 definitive 0.972 218 114 1990 2020
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.300 None 1.000 2 0 1992 2004
Entrez Id: 1829
Gene Symbol: DSG2
DSG2
Q14126 desmoglein 2 Cell adhesion 83 0.601 0.692 2.8E-10 0.020 None 1.000 2 1 1992 2005
Entrez Id: 1828
Gene Symbol: DSG1
DSG1
Q02413 desmoglein 1 Cell adhesion 81 0.606 0.538 0.93 0.010 None 1.000 1 0 1992 1992
Entrez Id: 4292
Gene Symbol: MLH1
MLH1
P40692 mutL homolog 1 Nucleic acid binding 526 0.399 0.808 3.4E-05 0.040 None 1.000 4 1 1996 2013
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1234 0.314 0.962 1.00 0.300 None 1.000 4 0 1999 2012
Entrez Id: 4869
Gene Symbol: NPM1
NPM1
P06748 nucleophosmin 1 Chaperone 283 0.464 0.846 1.00 0.300 None 1.000 1 0 1999 1999
Entrez Id: 6648
Gene Symbol: SOD2
SOD2
P04179 superoxide dismutase 2 Enzyme 668 0.379 0.923 0.15 0.300 None 1.000 4 0 2000 2014
Entrez Id: 11200
Gene Symbol: CHEK2
CHEK2
O96017 checkpoint kinase 2 Kinase 297 0.460 0.808 1.2E-24 0.310 None 1.000 2 0 2000 2011
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
P01116 KRAS proto-oncogene, GTPase Enzyme modulator 1213 0.320 0.923 7.9E-04 0.400 None 1.000 2 1 2000 2001
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.360 None 1.000 8 1 2001 2017
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
P01112 HRas proto-oncogene, GTPase Enzyme modulator 698 0.378 0.885 8.0E-02 0.300 None 1.000 2 0 2001 2015
Entrez Id: 51343
Gene Symbol: FZR1
FZR1
Q9UM11 fizzy and cell division cycle 20 related 1 Enzyme modulator 40 0.670 0.538 1.00 0.020 None 1.000 2 0 2001 2008
Entrez Id: 324
Gene Symbol: APC
APC
P25054 APC regulator of WNT signaling pathway 703 0.373 0.962 1.00 0.320 None 1.000 2 0 2001 2011
Entrez Id: 7048
Gene Symbol: TGFBR2
TGFBR2
P37173 transforming growth factor beta receptor 2 Kinase 502 0.413 0.846 0.13 0.010 None 1.000 1 0 2001 2001
Entrez Id: 1548
Gene Symbol: CYP2A6
CYP2A6
P11509 cytochrome P450 family 2 subfamily A member 6 133 0.556 0.731 5.4E-09 0.300 None 1.000 2 0 2002 2011
Entrez Id: 196
Gene Symbol: AHR
AHR
P35869 aryl hydrocarbon receptor Transcription factor 532 0.410 0.923 1.00 0.300 None 1.000 1 0 2002 2002
Entrez Id: 2272
Gene Symbol: FHIT
FHIT
P49789 fragile histidine triad diadenosine triphosphatase 337 0.444 0.846 5.7E-03 0.300 None 1.000 1 0 2003 2003
Entrez Id: 4502
Gene Symbol: MT2A
MT2A
P02795 metallothionein 2A 117 0.553 0.808 1.2E-05 0.300 None 1.000 1 0 2003 2003
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
P01584 interleukin 1 beta 1801 0.276 0.962 0.13 0.300 None 1.000 3 0 2004 2012
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
P04626 erb-b2 receptor tyrosine kinase 2 Kinase 995 0.328 0.923 6.0E-03 0.300 None 1.000 3 0 2004 2011