Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 1044 0.327 0.923 0.98 0.100 None 1.000 20 0 2010 2020
Entrez Id: 7809
Gene Symbol: BSND
BSND
Q8WZ55 barttin CLCNK type accessory subunit beta 91 0.603 0.692 1.1E-10 0.100 None 1.000 19 0 2007 2019
Entrez Id: 23583
Gene Symbol: SMUG1
SMUG1
Q53HV7 single-strand-selective monofunctional uracil-DNA glycosylase 1 1034 0.322 0.923 4.5E-04 0.100 None 1.000 18 0 2017 2019
Entrez Id: 3105
Gene Symbol: HLA-A
HLA-A
P04439 major histocompatibility complex, class I, A 672 0.370 0.846 1.3E-03 0.200 None 0.944 18 10 1983 2017
Entrez Id: 3586
Gene Symbol: IL10
IL10
P22301 interleukin 10 1679 0.281 0.923 5.9E-03 0.100 None 0.944 18 5 1997 2019
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1234 0.314 0.962 1.00 0.100 None 1.000 18 1 2001 2019
Entrez Id: 115482713
Gene Symbol: H3P10
H3P10
H3 histone pseudogene 10 769 0.350 0.846 0.100 None 1.000 17 0 1995 2019
Entrez Id: 51754
Gene Symbol: TMEM8B
TMEM8B
A6NDV4 transmembrane protein 8B Cell adhesion 26 0.736 0.346 2.8E-06 0.100 None 1.000 17 0 2002 2018
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
P01137 transforming growth factor beta 1 Signaling 1558 0.287 0.962 3.7E-02 0.100 None 0.882 17 1 1994 2019
Entrez Id: 2146
Gene Symbol: EZH2
EZH2
Q15910 enhancer of zeste 2 polycomb repressive complex 2 subunit Epigenetic regulator 653 0.376 0.885 1.00 0.100 None 1.000 16 0 2010 2019
Entrez Id: 4193
Gene Symbol: MDM2
MDM2
Q00987 MDM2 proto-oncogene Nucleic acid binding 702 0.362 0.846 1.00 0.100 None 0.938 16 3 2000 2019
Entrez Id: 2067
Gene Symbol: ERCC1
ERCC1
P07992 ERCC excision repair 1, endonuclease non-catalytic subunit Enzyme 345 0.445 0.846 1.6E-07 0.400 None 1.000 15 0 2009 2019
Entrez Id: 10577
Gene Symbol: NPC2
NPC2
P61916 NPC intracellular cholesterol transporter 2 81 0.612 0.769 1.8E-03 0.100 None 1.000 14 0 2001 2020
Entrez Id: 648
Gene Symbol: BMI1
BMI1
P35226 BMI1 proto-oncogene, polycomb ring finger 309 0.448 0.808 0.94 0.100 None 0.929 14 0 2006 2017
Entrez Id: 7515
Gene Symbol: XRCC1
XRCC1
P18887 X-ray repair cross complementing 1 410 0.421 0.923 6.3E-09 0.100 None 0.929 14 3 2003 2018
Entrez Id: 811
Gene Symbol: CALR
CALR
P27797 calreticulin Calcium-binding protein 487 0.413 0.923 0.89 0.100 None 1.000 14 0 2017 2019
Entrez Id: 836
Gene Symbol: CASP3
CASP3
P42574 caspase 3 Enzyme 819 0.351 0.923 0.10 0.100 None 1.000 14 0 2006 2019
Entrez Id: 960
Gene Symbol: CD44
CD44
P16070 CD44 molecule (Indian blood group) 711 0.363 0.962 2.4E-07 0.100 None 1.000 14 2 2007 2019
Entrez Id: 4609
Gene Symbol: MYC
MYC
P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 821 0.344 0.923 1.00 0.100 None 1.000 13 2 1997 2020
Entrez Id: 100532731
Gene Symbol: COMMD3-BMI1
COMMD3-BMI1
P35226 COMMD3-BMI1 readthrough 202 0.488 0.769 1.5E-03 0.100 None 0.917 12 0 2006 2017
Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1
P09488 glutathione S-transferase mu 1 627 0.380 0.923 2.1E-03 0.100 None 1.000 12 0 1999 2019
Entrez Id: 3569
Gene Symbol: IL6
IL6
P05231 interleukin 6 2367 0.248 0.962 0.32 0.100 None 1.000 12 0 2004 2014
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
P10145 C-X-C motif chemokine ligand 8 Signaling 1254 0.310 0.962 2.7E-04 0.100 None 1.000 12 0 2001 2018
Entrez Id: 4312
Gene Symbol: MMP1
MMP1
P03956 matrix metallopeptidase 1 Enzyme 589 0.385 0.885 7.7E-18 0.100 None 0.917 12 1 2003 2019
Entrez Id: 51297
Gene Symbol: BPIFA1
BPIFA1
Q9NP55 BPI fold containing family A member 1 67 0.617 0.577 1.2E-08 0.100 None 1.000 12 3 2003 2020