Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 55288
Gene Symbol: RHOT1
RHOT1
Q8IXI2 ras homolog family member T1 Enzyme modulator 20 0.722 0.308 0.80 0.010 None < 0.001 1 0 2019 2019
Entrez Id: 1981
Gene Symbol: EIF4G1
EIF4G1
Q04637 eukaryotic translation initiation factor 4 gamma 1 Nucleic acid binding 139 0.553 0.808 1.00 0.010 None < 0.001 1 2 2013 2013
Entrez Id: 79705
Gene Symbol: LRRK1
LRRK1
Q38SD2 leucine rich repeat kinase 1 Kinase 14 0.780 0.115 4.5E-10 0.010 None < 0.001 1 0 2017 2017
Entrez Id: 1636
Gene Symbol: ACE
ACE
P12821 angiotensin I converting enzyme Enzyme 1082 0.328 0.923 1.0E-37 0.010 None < 0.001 1 0 2009 2009
Entrez Id: 831
Gene Symbol: CAST
CAST
P20810 calpastatin 141 0.541 0.846 4.1E-12 0.010 None < 0.001 1 2 2013 2013
Entrez Id: 9360
Gene Symbol: PPIG
PPIG
Q13427 peptidylprolyl isomerase G 203 0.497 0.846 0.96 0.010 None < 0.001 1 0 1996 1996
Entrez Id: 3586
Gene Symbol: IL10
IL10
P22301 interleukin 10 1679 0.281 0.923 5.9E-03 0.030 None 0.333 3 0 2007 2012
Entrez Id: 5309
Gene Symbol: PITX3
PITX3
O75364 paired like homeodomain 3 93 0.585 0.692 0.81 0.020 None 0.500 2 0 2009 2011
Entrez Id: 6620
Gene Symbol: SNCB
SNCB
Q16143 synuclein beta Transporter 60 0.619 0.577 6.8E-02 0.020 None 0.500 2 0 2010 2010
Entrez Id: 6623
Gene Symbol: SNCG
SNCG
O76070 synuclein gamma Transporter 122 0.550 0.615 8.5E-04 0.020 None 0.500 2 0 2010 2010
Entrez Id: 3606
Gene Symbol: IL18
IL18
Q14116 interleukin 18 750 0.365 0.923 3.1E-02 0.020 None 0.500 2 0 2011 2019
Entrez Id: 4521
Gene Symbol: NUDT1
NUDT1
P36639 nudix hydrolase 1 Enzyme 73 0.597 0.769 7.4E-12 0.020 None 0.500 2 2 2000 2008
Entrez Id: 55737
Gene Symbol: VPS35
VPS35
Q96QK1 VPS35 retromer complex component Transporter 66 0.656 0.500 0.97 0.040 None 0.750 4 1 2013 2016
Entrez Id: 348
Gene Symbol: APOE
APOE
P02649 apolipoprotein E 1049 0.338 0.962 1.9E-03 0.050 None 0.800 5 0 1997 2015
Entrez Id: 1312
Gene Symbol: COMT
COMT
P21964 catechol-O-methyltransferase Enzyme 622 0.400 0.923 1.1E-06 0.060 None 0.833 6 0 2002 2014
Entrez Id: 1121
Gene Symbol: CHM
CHM
P24386 CHM Rab escort protein Enzyme 82 0.592 0.654 1.00 0.060 None 0.833 6 1 2003 2020
Entrez Id: 5071
Gene Symbol: PRKN
PRKN
O60260 parkin RBR E3 ubiquitin protein ligase Enzyme 409 0.431 0.846 6.9E-07 0.100 None 0.867 15 3 1999 2019
Entrez Id: 2629
Gene Symbol: GBA
GBA
P04062 glucosylceramidase beta 319 0.500 0.808 1.4E-06 0.090 None 0.889 9 1 2010 2019
Entrez Id: 7345
Gene Symbol: UCHL1
UCHL1
P09936 ubiquitin C-terminal hydrolase L1 Enzyme 260 0.482 0.885 0.99 0.090 None 0.889 9 2 2001 2017
Entrez Id: 6622
Gene Symbol: SNCA
SNCA
P37840 synuclein alpha Transporter 449 0.427 0.885 0.88 0.100 None 0.941 68 5 1998 2020
Entrez Id: 120892
Gene Symbol: LRRK2
LRRK2
Q5S007 leucine rich repeat kinase 2 Kinase 231 0.510 0.808 2.6E-30 0.100 None 0.971 102 8 2005 2020
Entrez Id: 65018
Gene Symbol: PINK1
PINK1
Q9BXM7 PTEN induced kinase 1 Kinase 209 0.516 0.769 1.9E-10 0.070 None 1.000 7 0 2006 2018
Entrez Id: 6531
Gene Symbol: SLC6A3
SLC6A3
Q01959 solute carrier family 6 member 3 Transporter 373 0.453 0.885 1.00 0.040 None 1.000 4 2 1997 2019
Entrez Id: 4129
Gene Symbol: MAOB
MAOB
P27338 monoamine oxidase B 152 0.533 0.808 1.00 0.040 None 1.000 4 0 2004 2012
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.030 None 1.000 3 0 2001 2018