×
Entrez Id:
114548
Gene Symbol:
NLRP3
NLRP3
0.310
GeneticVariation
disease
BEFREE
A dual luciferase reporter assay was performed to determine whether the SNP rs10754558 might be responsible for the altered NLRP3 gene expression in AV by disrupting the interaction between micro-RNA (miR)-4273 and NLRP3 mRNA.
29888470
2019
×
Entrez Id:
114548
Gene Symbol:
NLRP3
NLRP3
0.310
Biomarker
disease
CTD_human
Pyoderma gangrenosum and its syndromic forms: evidence for a link with autoinflammation.
27106250
2016
×
Entrez Id:
4210
Gene Symbol:
MEFV
MEFV
0.300
Biomarker
disease
CTD_human
Pyoderma gangrenosum and its syndromic forms: evidence for a link with autoinflammation.
27106250
2016
×
Entrez Id:
64127
Gene Symbol:
NOD2
NOD2
0.300
Biomarker
disease
CTD_human
Pyoderma gangrenosum and its syndromic forms: evidence for a link with autoinflammation.
27106250
2016
×
Entrez Id:
9051
Gene Symbol:
PSTPIP1
PSTPIP1
0.300
Biomarker
disease
CTD_human
Pyoderma gangrenosum and its syndromic forms: evidence for a link with autoinflammation.
27106250
2016
×
Entrez Id:
54984
Gene Symbol:
PINX1
PINX1
0.100
GeneticVariation
disease
GWASCAT
Genome-wide meta-analysis implicates mediators of hair follicle development and morphogenesis in risk for severe acne.
30542056
2018
×
Entrez Id:
79783
Gene Symbol:
SUGCT
SUGCT
0.100
GeneticVariation
disease
GWASCAT
Genome-wide meta-analysis implicates mediators of hair follicle development and morphogenesis in risk for severe acne.
30542056
2018
C11orf49
0.100
GeneticVariation
disease
GWASCAT
Two new susceptibility loci 1q24.2 and 11p11.2 confer risk to severe acne.
24399259
2014
×
Entrez Id:
80326
Gene Symbol:
WNT10A
WNT10A
0.100
GeneticVariation
disease
GWASCAT
Genome-wide meta-analysis implicates mediators of hair follicle development and morphogenesis in risk for severe acne.
30542056
2018
LYPLAL1-DT
0.100
GeneticVariation
disease
GWASCAT
Genome-wide meta-analysis implicates mediators of hair follicle development and morphogenesis in risk for severe acne.
30542056
2018
ADORA2A-AS1
0.100
GeneticVariation
disease
GWASCAT
Genome-wide association study identifies three novel susceptibility loci for severe Acne vulgaris.
24927181
2014
ADORA2A-AS1
0.100
GeneticVariation
disease
GWASCAT
Genome-wide meta-analysis implicates mediators of hair follicle development and morphogenesis in risk for severe acne.
30542056
2018
×
Entrez Id:
1936
Gene Symbol:
EEF1D
EEF1D
0.100
GeneticVariation
disease
GWASCAT
Japanese GWAS identifies variants for bust-size, dysmenorrhea, and menstrual fever that are eQTLs for relevant protein-coding or long non-coding RNAs.
29855537
2018
C1orf112
0.100
GeneticVariation
disease
GWASCAT
Two new susceptibility loci 1q24.2 and 11p11.2 confer risk to severe acne.
24399259
2014
×
Entrez Id:
10509
Gene Symbol:
SEMA4B
SEMA4B
0.100
GeneticVariation
disease
GWASCAT
Genome-wide meta-analysis implicates mediators of hair follicle development and morphogenesis in risk for severe acne.
30542056
2018
×
Entrez Id:
399909
Gene Symbol:
PCNX3
PCNX3
0.100
GeneticVariation
disease
GWASCAT
Genome-wide meta-analysis implicates mediators of hair follicle development and morphogenesis in risk for severe acne.
30542056
2018
×
Entrez Id:
7324
Gene Symbol:
UBE2E1
UBE2E1
0.100
GeneticVariation
disease
GWASCAT
Genome-wide association study identifies three novel susceptibility loci for severe Acne vulgaris.
24927181
2014
×
Entrez Id:
7124
Gene Symbol:
TNF
TNF
0.060
GeneticVariation
disease
BEFREE
This case-control study investigated the association of the TNF -308 G>A and -238 G>A SNPs with acne vulgaris in a high-risk Pakistani population.
26373312
2016
×
Entrez Id:
7124
Gene Symbol:
TNF
TNF
0.060
GeneticVariation
disease
BEFREE
Tumor necrosis factor-α -308 G/A and interleukin 10 -1082 A/G gene polymorphisms in patients with acne vulgaris .
22835835
2012
×
Entrez Id:
7124
Gene Symbol:
TNF
TNF
0.060
GeneticVariation
disease
BEFREE
Carriage of the GAG haplotype of TNF is linked with borderline susceptibility to acne vulgaris .
24334867
2014
×
Entrez Id:
7124
Gene Symbol:
TNF
TNF
0.060
GeneticVariation
disease
BEFREE
Genetic variants of the TNFα gene may affect the risk of acne vulgaris .
20386917
2011
×
Entrez Id:
7124
Gene Symbol:
TNF
TNF
0.060
GeneticVariation
disease
BEFREE
This meta-analysis suggests that the -308 G/A polymorphism in the TNF gene contributes to acne vulgaris risk, especially in Caucasian populations.
24498378
2014
×
Entrez Id:
7124
Gene Symbol:
TNF
TNF
0.060
GeneticVariation
disease
BEFREE
Association study of tumor necrosis factor receptor type 2 M196R and toll-like receptor 2 Arg753Gln polymorphisms with acne vulgaris in a Chinese Han ethnic group.
20861605
2010
×
Entrez Id:
3553
Gene Symbol:
IL1B
IL1B
0.050
Biomarker
disease
BEFREE
In particular, the IL-1 family of cytokines has a critical role in both initiation of acne lesions and in the inflammatory response in acne.
23884315
2014
×
Entrez Id:
3553
Gene Symbol:
IL1B
IL1B
0.050
Biomarker
disease
BEFREE
Recent findings have revealed that excessive IL-1 release induced by harmful stimuli likely contributes to the pathogenesis of common dermatological diseases such as acne vulgaris or seborrheic dermatitis.
28588486
2017