Source: CURATED ×
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 324
Gene Symbol: APC
APC 		0.900 Biomarker group CTD_human 4-Hydroxy-2(E)-nonenal metabolism differs in Apc(+/+) cells and in Apc(Min/+) cells: it may explain colon cancer promotion by heme iron. 21967605 2011
Entrez Id: 324
Gene Symbol: APC
APC 		0.900 Biomarker group CTD_human Antihelminth compound niclosamide downregulates Wnt signaling and elicits antitumor responses in tumors with activating APC mutations. 21531761 2011
Entrez Id: 324
Gene Symbol: APC
APC 		0.900 Biomarker group CTD_human Fluorinated N,N-dialkylaminostilbenes for Wnt pathway inhibition and colon cancer repression. 21291235 2011
Entrez Id: 324
Gene Symbol: APC
APC 		0.900 Biomarker group CTD_human The association of methylation in the promoter of APC and MGMT and the prognosis of Taiwanese CRC patients. 19309276 2009
Entrez Id: 324
Gene Symbol: APC
APC 		0.900 Biomarker group CTD_human Epigenetic regulation of WNT signaling pathway genes in inflammatory bowel disease (IBD) associated neoplasia. 18716850 2008
Entrez Id: 324
Gene Symbol: APC
APC 		0.900 Biomarker group CTD_human Dietary folate and APC mutations in sporadic colorectal cancer. 17116713 2006
Entrez Id: 324
Gene Symbol: APC
APC 		0.900 Biomarker group CTD_human Proteomic analysis of intestinal epithelial cells expressing stabilized beta-catenin. 12907644 2003
Entrez Id: 324
Gene Symbol: APC
APC 		0.900 GeneticVariation group UNIPROT
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1 		0.700 Biomarker group CTD_human Resveratrol prevents tumorigenesis in mouse model of Kras activated sporadic colorectal cancer by suppressing oncogenic Kras expression. 25280562 2014
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1 		0.700 Biomarker group CTD_human Fluorinated N,N-dialkylaminostilbenes for Wnt pathway inhibition and colon cancer repression. 21291235 2011
Entrez Id: 4313
Gene Symbol: MMP2
MMP2 		0.700 Biomarker group CTD_human Genomic and epigenomic integration identifies a prognostic signature in colon cancer. 21278247 2011
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.700 Biomarker group CTD_human A germline variant in the TP53 polyadenylation signal confers cancer susceptibility. 21946351 2011
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.700 Biomarker group CTD_human The predictive value of p53 and p33(ING1b) in patients with Dukes'C colorectal cancer. 17949449 2008
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.700 Biomarker group CTD_human K-Ras mutations and treatment outcome in colorectal cancer patients receiving exclusive fluoropyrimidine therapy. 18676755 2008
Entrez Id: 4313
Gene Symbol: MMP2
MMP2 		0.700 Biomarker group CTD_human Convergence of mutation and epigenetic alterations identifies common genes in cancer that predict for poor prognosis. 18507500 2008
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.700 Biomarker group CTD_human Functional categories of TP53 mutation in colorectal cancer: results of an International Collaborative Study. 16524972 2006
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.700 Biomarker group CTD_human Variance in the expression of 5-Fluorouracil pathway genes in colorectal cancer. 15814641 2005
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.700 Biomarker group CTD_human Determination of TP53 mutation is more relevant than microsatellite instability status for the prediction of disease-free survival in adjuvant-treated stage III colon cancer patients. 16110022 2005
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.700 Biomarker group CTD_human p53 is an independent pre-treatment markers for long-term survival in stage II and III colorectal cancers: an analysis of interaction between genetic markers and fluorouracil-based adjuvant therapy. 15172127 2004
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.700 Biomarker group CTD_human Correlation of Ki-67, p53, and Adnab-9 immunohistochemical staining and ploidy with clinical and histopathologic features of severely dysplastic colorectal adenomas. 12645814 2003
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1 		0.700 Biomarker group CTD_human Proteomic analysis of intestinal epithelial cells expressing stabilized beta-catenin. 12907644 2003
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1 		0.700 Biomarker group CTD_human More frequent beta-catenin gene mutations in adenomas than in aberrant crypt foci or adenocarcinomas in the large intestines of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)-treated rats. 10965019 2000
Entrez Id: 7298
Gene Symbol: TYMS
TYMS 		0.600 Biomarker group CTD_human Highly Expressed Genes in Rapidly Proliferating Tumor Cells as New Targets for Colorectal Cancer Treatment. 25944804 2015
Entrez Id: 7298
Gene Symbol: TYMS
TYMS 		0.600 Biomarker group CTD_human Prognostic significance of numeric aberrations of genes for thymidylate synthase, thymidine phosphorylase and dihydrofolate reductase in colorectal cancer. 18607850 2008
Entrez Id: 7298
Gene Symbol: TYMS
TYMS 		0.600 Biomarker group CTD_human K-Ras mutations and treatment outcome in colorectal cancer patients receiving exclusive fluoropyrimidine therapy. 18676755 2008