Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2952
Gene Symbol: GSTT1
GSTT1 		0.020 GeneticVariation group LHGDN The GSTM1 and GSTT1 gene polymorphisms seem to be associated with the development of drug eruption. 14740231 2004
Entrez Id: 2952
Gene Symbol: GSTT1
GSTT1 		0.020 GeneticVariation group BEFREE The GSTM1 and GSTT1 gene polymorphisms seem to be associated with the development of drug eruption. 14740231 2004
Entrez Id: 2952
Gene Symbol: GSTT1
GSTT1 		0.020 GeneticVariation group BEFREE The GSTP1 Val/Val genotype was significantly associated with non-photosensitive drug eruptions (OR = 3.64, P value = 0.038), whereas associations observed between GSTP1, GSTM1, GSTT1 polymorphisms and photosensitive drug eruptions did not reach statistical significance. 30737837 2019
Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1 		0.020 GeneticVariation group BEFREE Variations in GSTP1 may affect the risk to develop non-photo-induced drug eruptions. 30737837 2019
Entrez Id: 27306
Gene Symbol: HPGDS
HPGDS 		0.020 GeneticVariation group BEFREE Glutathione S-transferase polymorphisms in patients with photosensitive and non-photosensitive drug eruptions. 30737837 2019
Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1 		0.020 GeneticVariation group BEFREE The GSTM1 and GSTT1 gene polymorphisms seem to be associated with the development of drug eruption. 14740231 2004
Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1 		0.020 GeneticVariation group LHGDN The GSTM1 and GSTT1 gene polymorphisms seem to be associated with the development of drug eruption. 14740231 2004
Entrez Id: 27306
Gene Symbol: HPGDS
HPGDS 		0.020 GeneticVariation group BEFREE Glutathione S-transferase polymorphisms in patients with drug eruption. 14740231 2004
Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1 		0.020 GeneticVariation group BEFREE Our results show that GSTP1 polymorphism is not a significant contributor to drug eruption risk. 14740231 2004
Entrez Id: 3105
Gene Symbol: HLA-A
HLA-A 		0.010 GeneticVariation group BEFREE HLA-A*02 alleles are associated with tetanus antitoxin-induced exanthematous drug eruptions in Chinese patients. 27749688 2016
Entrez Id: 133482
Gene Symbol: SLCO6A1
SLCO6A1 		0.010 GeneticVariation group BEFREE Detoxification features make it plausible to search for GST polymorphism in patients with drug eruption. 14740231 2004
Entrez Id: 373156
Gene Symbol: GSTK1
GSTK1 		0.010 GeneticVariation group BEFREE Detoxification features make it plausible to search for GST polymorphism in patients with drug eruption. 14740231 2004
Entrez Id: 3106
Gene Symbol: HLA-B
HLA-B 		0.320 Biomarker group BEFREE A strong association between the HLA-B*3505 and NVP-induced skin rash provides a novel insight into the pathogenesis of drug-induced rash in the HIV-infected population. 19104471 2009
Entrez Id: 3106
Gene Symbol: HLA-B
HLA-B 		0.320 Biomarker group CTD_human [Correlation, in previously treated HIV-1 positive patients, between hypersensitivity reaction to abacavir and the presence of the HLA-B*5701 allele]. 19712599 2010
Entrez Id: 3106
Gene Symbol: HLA-B
HLA-B 		0.320 Biomarker group BEFREE Drug eruptions induced by allopurinol associated with HLA-B*5801. 25566896 2015
Entrez Id: 3106
Gene Symbol: HLA-B
HLA-B 		0.320 Biomarker group CTD_human Association Between HLA genotypes and Oxcarbazepine-induced Cutaneous Adverse Drug Reactions: A Systematic Review and Meta-Analysis. 29370880 2018
Entrez Id: 3458
Gene Symbol: IFNG
IFNG 		0.310 Biomarker group BEFREE Direct evidence for interferon-gamma production by effector-memory-type intraepidermal T cells residing at an effector site of immunopathology in fixed drug eruption. 12368207 2002
Entrez Id: 3458
Gene Symbol: IFNG
IFNG 		0.310 Biomarker group CTD_human Effect of trichloroacetaldehyde on the activation of CD4+T cells in occupational medicamentosa-like dermatitis: An in vivo and in vitro study. 31150805 2019
Entrez Id: 7124
Gene Symbol: TNF
TNF 		0.310 Biomarker group CTD_human Effect of trichloroacetaldehyde on the activation of CD4+T cells in occupational medicamentosa-like dermatitis: An in vivo and in vitro study. 31150805 2019
Entrez Id: 7124
Gene Symbol: TNF
TNF 		0.310 Biomarker group BEFREE The present case indicates that tumor necrosis factor-α antagonist is a safe, fast and effective treatment for severe drug eruption, but it is unable to prevent the rise of peripheral blood eosinophils. 29285114 2017
Entrez Id: 5970
Gene Symbol: RELA
RELA 		0.300 Biomarker group CTD_human Effect of trichloroacetaldehyde on the activation of CD4+T cells in occupational medicamentosa-like dermatitis: An in vivo and in vitro study. 31150805 2019
Entrez Id: 1571
Gene Symbol: CYP2E1
CYP2E1 		0.300 Biomarker group CTD_human [Relationship between gene polymorphism of CYP2E1, CYP1A1, IL-4 and medicamentosa-like dermatitis induced by trichloroethylene]. 19351467 2009
Entrez Id: 3115
Gene Symbol: HLA-DPB1
HLA-DPB1 		0.300 Biomarker group CTD_human Genetic markers for differentiating aspirin-hypersensitivity. 16502481 2006
Entrez Id: 240
Gene Symbol: ALOX5
ALOX5 		0.300 Biomarker group CTD_human Genetic markers for differentiating aspirin-hypersensitivity. 16502481 2006
Entrez Id: 3606
Gene Symbol: IL18
IL18 		0.300 Biomarker group CTD_human Neutrophil activation in patients with ASA-induced urticaria. 18204966 2008