Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
0.010 Biomarker group BEFREE Epidermal growth factor receptor (EGFR) inhibitor induced purpuric drug eruption: Three case reports. 31764850 2019
Entrez Id: 367
Gene Symbol: AR
AR
0.010 Biomarker group BEFREE Drug eruption caused by enzalutamide: A case and literature review of androgen receptor inhibitor-related drug eruptions. 29878315 2018
Entrez Id: 1401
Gene Symbol: CRP
CRP
0.010 Biomarker group BEFREE About PsE and DE, significant elevation of C-reactive protein was observed. 29590497 2018
Entrez Id: 2875
Gene Symbol: GPT
GPT
0.010 AlteredExpression group BEFREE Aspartate aminotransferase and alanine aminotransferase were also elevated in DE. 29590497 2018
Entrez Id: 3105
Gene Symbol: HLA-A
HLA-A
0.010 GeneticVariation group BEFREE HLA-A*02 alleles are associated with tetanus antitoxin-induced exanthematous drug eruptions in Chinese patients. 27749688 2016
Entrez Id: 406996
Gene Symbol: MIR214
MIR214
0.010 Biomarker group BEFREE We investigated miR-124 and miR-214 expressions in serum and skin tissues of severe drug eruptions to evaluate the possibility of biomarkers of TEN. 26394757 2016
Entrez Id: 3447
Gene Symbol: IFNA13
IFNA13
0.010 Biomarker group BEFREE Here, we aimed to investigate the immunological mechanisms underlying pegylated IFN-α-induced drug eruptions. 25831972 2015
Entrez Id: 3439
Gene Symbol: IFNA1
IFNA1
0.010 Biomarker group BEFREE Here, we aimed to investigate the immunological mechanisms underlying pegylated IFN-α-induced drug eruptions. 25831972 2015
Entrez Id: 406953
Gene Symbol: MIR18A
MIR18A
0.010 AlteredExpression group BEFREE Serum miR-18a-5p levels can be a useful disease marker for drug eruptions. 24184144 2014
Entrez Id: 133482
Gene Symbol: SLCO6A1
SLCO6A1
0.010 GeneticVariation group BEFREE Detoxification features make it plausible to search for GST polymorphism in patients with drug eruption. 14740231 2004
Entrez Id: 373156
Gene Symbol: GSTK1
GSTK1
0.010 GeneticVariation group BEFREE Detoxification features make it plausible to search for GST polymorphism in patients with drug eruption. 14740231 2004
Entrez Id: 9360
Gene Symbol: PPIG
PPIG
0.010 AlteredExpression group BEFREE The measures for the drug profiles were medicine type (ATC-code), mono- and polypharmacy, CYP-enzyme metabolism pattern, and medicine with a potential to induce lichenoid drug eruptions. 12974517 2003
Entrez Id: 472
Gene Symbol: ATM
ATM
0.010 Biomarker group BEFREE The measures for the drug profiles were medicine type (ATC-code), mono- and polypharmacy, CYP-enzyme metabolism pattern, and medicine with a potential to induce lichenoid drug eruptions. 12974517 2003
Entrez Id: 2952
Gene Symbol: GSTT1
GSTT1
0.020 GeneticVariation group BEFREE The GSTP1 Val/Val genotype was significantly associated with non-photosensitive drug eruptions (OR = 3.64, P value = 0.038), whereas associations observed between GSTP1, GSTM1, GSTT1 polymorphisms and photosensitive drug eruptions did not reach statistical significance. 30737837 2019
Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1
0.020 GeneticVariation group BEFREE Variations in GSTP1 may affect the risk to develop non-photo-induced drug eruptions. 30737837 2019
Entrez Id: 27306
Gene Symbol: HPGDS
HPGDS
0.020 GeneticVariation group BEFREE Glutathione S-transferase polymorphisms in patients with photosensitive and non-photosensitive drug eruptions. 30737837 2019
Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1
0.020 Biomarker group BEFREE The GSTP1 Val/Val genotype was significantly associated with non-photosensitive drug eruptions (OR = 3.64, P value = 0.038), whereas associations observed between GSTP1, GSTM1, GSTT1 polymorphisms and photosensitive drug eruptions did not reach statistical significance. 30737837 2019
Entrez Id: 6361
Gene Symbol: CCL17
CCL17
0.020 Biomarker group BEFREE The aim of this study was to test whether the thymus and activation-regulated chemokine (TARC) level in serum at an early stage of a drug eruption can serve as a prognostic biomarker of systemic inflammation. 28648978 2018
Entrez Id: 6361
Gene Symbol: CCL17
CCL17
0.020 AlteredExpression group BEFREE Serum TARC levels are strongly correlated with blood eosinophil count in patients with drug eruptions. 27497618 2017
Entrez Id: 2952
Gene Symbol: GSTT1
GSTT1
0.020 GeneticVariation group LHGDN The GSTM1 and GSTT1 gene polymorphisms seem to be associated with the development of drug eruption. 14740231 2004
Entrez Id: 2952
Gene Symbol: GSTT1
GSTT1
0.020 GeneticVariation group BEFREE The GSTM1 and GSTT1 gene polymorphisms seem to be associated with the development of drug eruption. 14740231 2004
Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1
0.020 GeneticVariation group BEFREE The GSTM1 and GSTT1 gene polymorphisms seem to be associated with the development of drug eruption. 14740231 2004
Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1
0.020 GeneticVariation group LHGDN The GSTM1 and GSTT1 gene polymorphisms seem to be associated with the development of drug eruption. 14740231 2004
Entrez Id: 27306
Gene Symbol: HPGDS
HPGDS
0.020 GeneticVariation group BEFREE Glutathione S-transferase polymorphisms in patients with drug eruption. 14740231 2004
Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1
0.020 GeneticVariation group BEFREE Our results show that GSTP1 polymorphism is not a significant contributor to drug eruption risk. 14740231 2004