Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3106
Gene Symbol: HLA-B
HLA-B 		0.320 Biomarker group BEFREE Drug eruptions induced by allopurinol associated with HLA-B*5801. 25566896 2015
Entrez Id: 27306
Gene Symbol: HPGDS
HPGDS 		0.020 GeneticVariation group BEFREE Glutathione S-transferase polymorphisms in patients with drug eruption. 14740231 2004
Entrez Id: 3105
Gene Symbol: HLA-A
HLA-A 		0.010 GeneticVariation group BEFREE HLA-A*02 alleles are associated with tetanus antitoxin-induced exanthematous drug eruptions in Chinese patients. 27749688 2016
Entrez Id: 27306
Gene Symbol: HPGDS
HPGDS 		0.020 GeneticVariation group BEFREE Glutathione S-transferase polymorphisms in patients with photosensitive and non-photosensitive drug eruptions. 30737837 2019
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		0.010 Biomarker group BEFREE Epidermal growth factor receptor (EGFR) inhibitor induced purpuric drug eruption: Three case reports. 31764850 2019
Entrez Id: 3106
Gene Symbol: HLA-B
HLA-B 		0.320 Biomarker group BEFREE A strong association between the HLA-B*3505 and NVP-induced skin rash provides a novel insight into the pathogenesis of drug-induced rash in the HIV-infected population. 19104471 2009
Entrez Id: 1401
Gene Symbol: CRP
CRP 		0.010 Biomarker group BEFREE About PsE and DE, significant elevation of C-reactive protein was observed. 29590497 2018
Entrez Id: 2875
Gene Symbol: GPT
GPT 		0.010 AlteredExpression group BEFREE Aspartate aminotransferase and alanine aminotransferase were also elevated in DE. 29590497 2018
Entrez Id: 3106
Gene Symbol: HLA-B
HLA-B 		0.320 Biomarker group CTD_human Association Between HLA genotypes and Oxcarbazepine-induced Cutaneous Adverse Drug Reactions: A Systematic Review and Meta-Analysis. 29370880 2018
Entrez Id: 133482
Gene Symbol: SLCO6A1
SLCO6A1 		0.010 GeneticVariation group BEFREE Detoxification features make it plausible to search for GST polymorphism in patients with drug eruption. 14740231 2004
Entrez Id: 373156
Gene Symbol: GSTK1
GSTK1 		0.010 GeneticVariation group BEFREE Detoxification features make it plausible to search for GST polymorphism in patients with drug eruption. 14740231 2004
Entrez Id: 3458
Gene Symbol: IFNG
IFNG 		0.310 Biomarker group BEFREE Direct evidence for interferon-gamma production by effector-memory-type intraepidermal T cells residing at an effector site of immunopathology in fixed drug eruption. 12368207 2002
Entrez Id: 367
Gene Symbol: AR
AR 		0.010 Biomarker group BEFREE Drug eruption caused by enzalutamide: A case and literature review of androgen receptor inhibitor-related drug eruptions. 29878315 2018
Entrez Id: 3458
Gene Symbol: IFNG
IFNG 		0.310 Biomarker group CTD_human Effect of trichloroacetaldehyde on the activation of CD4+T cells in occupational medicamentosa-like dermatitis: An in vivo and in vitro study. 31150805 2019
Entrez Id: 7124
Gene Symbol: TNF
TNF 		0.310 Biomarker group CTD_human Effect of trichloroacetaldehyde on the activation of CD4+T cells in occupational medicamentosa-like dermatitis: An in vivo and in vitro study. 31150805 2019
Entrez Id: 5970
Gene Symbol: RELA
RELA 		0.300 Biomarker group CTD_human Effect of trichloroacetaldehyde on the activation of CD4+T cells in occupational medicamentosa-like dermatitis: An in vivo and in vitro study. 31150805 2019
Entrez Id: 3558
Gene Symbol: IL2
IL2 		0.300 Biomarker group CTD_human Effect of trichloroacetaldehyde on the activation of CD4+T cells in occupational medicamentosa-like dermatitis: An in vivo and in vitro study. 31150805 2019
Entrez Id: 3605
Gene Symbol: IL17A
IL17A 		0.300 Biomarker group CTD_human Effect of trichloroacetaldehyde on the activation of CD4+T cells in occupational medicamentosa-like dermatitis: An in vivo and in vitro study. 31150805 2019
Entrez Id: 3827
Gene Symbol: KNG1
KNG1 		0.300 Biomarker group CTD_human Effects of capsaicin, bradykinin and prostaglandin E2 in the human skin. 1371395 1992
Entrez Id: 3827
Gene Symbol: KNG1
KNG1 		0.300 Therapeutic group CTD_human Effects of capsaicin, bradykinin and prostaglandin E2 in the human skin. 1371395 1992
Entrez Id: 6863
Gene Symbol: TAC1
TAC1 		0.300 Biomarker group CTD_human Effects of capsaicin, bradykinin and prostaglandin E2 in the human skin. 1371395 1992
Entrez Id: 3827
Gene Symbol: KNG1
KNG1 		0.300 Biomarker group CTD_human Effects of intradermal bradykinin after inhibition of angiotensin converting enzyme. 3034372 1987
Entrez Id: 3827
Gene Symbol: KNG1
KNG1 		0.300 Therapeutic group CTD_human Effects of intradermal bradykinin after inhibition of angiotensin converting enzyme. 3034372 1987
Entrez Id: 3115
Gene Symbol: HLA-DPB1
HLA-DPB1 		0.300 Biomarker group CTD_human Genetic markers for differentiating aspirin-hypersensitivity. 16502481 2006
Entrez Id: 240
Gene Symbol: ALOX5
ALOX5 		0.300 Biomarker group CTD_human Genetic markers for differentiating aspirin-hypersensitivity. 16502481 2006