×
Entrez Id: 1469
Gene Symbol: CST1
CST1
0.320
Biomarker
disease
BEFREE
Moreover, interferon-inducible protein with tetratricopeptide repeats 1, cystatin 1 , and interferon-inducible protein with tetratricopeptide repeats 3 were found to be differentially regulated between patients with SAR and control subjects, with inverse abundance dynamics during the transition from fall to spring.
28633877 2017
×
Entrez Id: 1469
Gene Symbol: CST1
CST1
0.320
Biomarker
disease
CTD_human
Immunohistochemical staining confirmed the increased expression of CST1 in the nasal epithelial cells of SAR patients.
23950865 2013
×
Entrez Id: 1469
Gene Symbol: CST1
CST1
0.320
AlteredExpression
disease
BEFREE
Immunohistochemical staining confirmed the increased expression of CST1 in the nasal epithelial cells of SAR patients.
23950865 2013
×
Entrez Id: 7145
Gene Symbol: TNS1
TNS1
0.110
GeneticVariation
disease
BEFREE
Single nucleotide polymorphisms with suggestive evidence for association with asthma with hay fever risk included rs41295115 near IL2RA (OR, 1.28; P = 5 × 10(-7)) and rs76043829 in TNS1 (OR, 1.23; P = 2 × 10(-6)).
24388013 2014
×
Entrez Id: 4088
Gene Symbol: SMAD3
SMAD3
0.110
GeneticVariation
disease
GWASCAT
Genome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype.
24388013 2014
×
Entrez Id: 7145
Gene Symbol: TNS1
TNS1
0.110
GeneticVariation
disease
GWASCAT
Genome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype.
24388013 2014
×
Entrez Id: 3558
Gene Symbol: IL2
IL2
0.110
GeneticVariation
disease
GWASDB
A genome-wide meta-analysis of genetic variants associated with allergic rhinitis and grass sensitization and their interaction with birth order.
22036096 2011
×
Entrez Id: 3558
Gene Symbol: IL2
IL2
0.110
GeneticVariation
disease
GWASCAT
A genome-wide meta-analysis of genetic variants associated with allergic rhinitis and grass sensitization and their interaction with birth order.
22036096 2011
×
Entrez Id: 4088
Gene Symbol: SMAD3
SMAD3
0.110
AlteredExpression
disease
BEFREE
There were no significant differences between the rhinitic and non-rhinitic groups in the expression of TGF-beta isoforms or Smad-3 , Smad-6 and Smad-7 proteins; however, there was increased gene expression for TGF-betaRI and TGF-betaRII along with CTGF in seasonal allergic rhinitis .
18201469 2007
×
Entrez Id: 3558
Gene Symbol: IL2
IL2
0.110
GeneticVariation
disease
BEFREE
Homozygotes of the G-allele in IL-2 -330 T/G were at increased risk of hayfever (OR=2.6, 95%CI=1.3-5.2).
15005726 2004
×
Entrez Id: 286046
Gene Symbol: XKR6
XKR6
0.100
GeneticVariation
disease
GWASCAT
Genome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype.
24388013 2014
×
Entrez Id: 10451
Gene Symbol: VAV3
VAV3
0.100
GeneticVariation
disease
GWASCAT
Genome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype.
24388013 2014
×
Entrez Id: 7096
Gene Symbol: TLR1
TLR1
0.100
GeneticVariation
disease
GWASCAT
Genome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype.
24388013 2014
×
Entrez Id: 23274
Gene Symbol: CLEC16A
CLEC16A
0.100
GeneticVariation
disease
GWASCAT
Genome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype.
24388013 2014
×
Entrez Id: 9173
Gene Symbol: IL1RL1
IL1RL1
0.100
GeneticVariation
disease
GWASCAT
Genome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype.
24388013 2014
×
Entrez Id: 22806
Gene Symbol: IKZF3
IKZF3
0.100
GeneticVariation
disease
GWASCAT
Genome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype.
24388013 2014
×
Entrez Id: 8809
Gene Symbol: IL18R1
IL18R1
0.100
GeneticVariation
disease
GWASCAT
Genome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype.
24388013 2014
×
Entrez Id: 284110
Gene Symbol: GSDMA
GSDMA
0.100
GeneticVariation
disease
GWASCAT
Genome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype.
24388013 2014
×
Entrez Id: 23274
Gene Symbol: CLEC16A
CLEC16A
0.100
GeneticVariation
disease
GWASCAT
A genome-wide meta-analysis of genetic variants associated with allergic rhinitis and grass sensitization and their interaction with birth order.
22036096 2011
×
Entrez Id: 773
Gene Symbol: CACNA1A
CACNA1A
0.100
GeneticVariation
disease
CLINVAR
×
Entrez Id: 3269
Gene Symbol: HRH1
HRH1
0.030
AlteredExpression
disease
BEFREE
The H1R gene is upregulated in patients with pollinosis , and its expression level is correlated with the severity of nasal symptoms.
26980430 2016
×
Entrez Id: 90865
Gene Symbol: IL33
IL33
0.030
GeneticVariation
disease
BEFREE
IL-33 -polymorphisms rs928413 and rs1342326 may account for an increased risk of hay fever with the age of 6 years.27171815 2016
×
Entrez Id: 3269
Gene Symbol: HRH1
HRH1
0.030
AlteredExpression
disease
BEFREE
Effects of antihistamine on up-regulation of histamine H1 receptor mRNA in the nasal mucosa of patients with pollinosis induced by controlled cedar pollen challenge in an environmental exposure unit.
26598006 2015
×
Entrez Id: 90865
Gene Symbol: IL33
IL33
0.030
Biomarker
disease
BEFREE
The IL-33 -induced production of pro-inflammatory cytokines is a critical event that aggravates atopic diseases such as asthma, atopic dermatitis, and pollenosis and suggests that IL-33 -blocking agents could represent new therapeutic drugs.
25213717 2014
×
Entrez Id: 3596
Gene Symbol: IL13
IL13
0.030
GeneticVariation
disease
BEFREE
Of 60 tagging single-nucleotide polymorphisms covering eight genes (CSF2, IL3, IL4, IL13, CSF2RB, IL4R, IL13RA1, IL13RA2), several were related to pollen allergies among controls: IL4R rs3024647 (dominant OR: 1.5; 95% CI: 1.0-2.3; P = 0.04), CSF2RB rs16997517 (dominant OR: 2.2; 95% CI: 1.0-4.7; P = 0.04), and IL13 rs1800925 (per-allele OR: 1.7; 95% CI: 1.3-2.4; P = 0.0007).
21071541 2011