rs7775228
|
|
C |
0.810 |
GeneticVariation |
GWASCAT |
The HLA variant rs7775228, which cis-regulates HLA-DRB4, was strongly associated with grass sensitization and weakly with AR (P(grass) = 1.6 × 10(-9); P(AR) = 8.0 × 10(-3)).
|
22036096 |
2011 |
rs7775228
|
|
|
0.810 |
GeneticVariation |
BEFREE |
The HLA variant rs7775228, which cis-regulates HLA-DRB4, was strongly associated with grass sensitization and weakly with AR (P(grass) = 1.6 × 10(-9); P(AR) = 8.0 × 10(-3)).
|
22036096 |
2011 |
rs7775228
|
|
C |
0.810 |
GeneticVariation |
GWASDB |
The HLA variant rs7775228, which cis-regulates HLA-DRB4, was strongly associated with grass sensitization and weakly with AR (P(grass) = 1.6 × 10(-9); P(AR) = 8.0 × 10(-3)).
|
22036096 |
2011 |
rs17513503
|
|
G |
0.800 |
GeneticVariation |
GWASCAT |
A genome-wide meta-analysis of genetic variants associated with allergic rhinitis and grass sensitization and their interaction with birth order.
|
22036096 |
2011 |
rs17513503
|
|
G |
0.800 |
GeneticVariation |
GWASDB |
A genome-wide meta-analysis of genetic variants associated with allergic rhinitis and grass sensitization and their interaction with birth order.
|
22036096 |
2011 |
rs2069772
|
|
C |
0.800 |
GeneticVariation |
GWASDB |
A genome-wide meta-analysis of genetic variants associated with allergic rhinitis and grass sensitization and their interaction with birth order.
|
22036096 |
2011 |
rs2069772
|
|
C |
0.800 |
GeneticVariation |
GWASCAT |
A genome-wide meta-analysis of genetic variants associated with allergic rhinitis and grass sensitization and their interaction with birth order.
|
22036096 |
2011 |
rs2155219
|
|
T |
0.800 |
GeneticVariation |
GWASDB |
Variants in a locus near chromosome 11 open reading frame 30 (C11orf30) and leucine-rich repeat containing 32 (LRRC32), which was previously associated with atopic dermatitis and eczema, were also strongly associated with both phenotypes (rs2155219; P(grass) = 9.4 × 10(-9); P(AR) = 3.8 × 10(-8)).
|
22036096 |
2011 |
rs2155219
|
|
T |
0.800 |
GeneticVariation |
GWASCAT |
Variants in a locus near chromosome 11 open reading frame 30 (C11orf30) and leucine-rich repeat containing 32 (LRRC32), which was previously associated with atopic dermatitis and eczema, were also strongly associated with both phenotypes (rs2155219; P(grass) = 9.4 × 10(-9); P(AR) = 3.8 × 10(-8)).
|
22036096 |
2011 |
rs41295115
|
|
|
0.710 |
GeneticVariation |
BEFREE |
Single nucleotide polymorphisms with suggestive evidence for association with asthma with hay fever risk included rs41295115 near IL2RA (OR, 1.28; P = 5 × 10(-7)) and rs76043829 in TNS1 (OR, 1.23; P = 2 × 10(-6)).
|
24388013 |
2014 |
rs41295115
|
|
C |
0.710 |
GeneticVariation |
GWASCAT |
Single nucleotide polymorphisms with suggestive evidence for association with asthma with hay fever risk included rs41295115 near IL2RA (OR, 1.28; P = 5 × 10(-7)) and rs76043829 in TNS1 (OR, 1.23; P = 2 × 10(-6)).
|
24388013 |
2014 |
rs62026376
|
|
C |
0.710 |
GeneticVariation |
GWASCAT |
The rs62026376:C allele associated with increased asthma with hay fever risk has been found to be associated also with decreased expression of the nearby DEXI gene in monocytes.
|
24388013 |
2014 |
rs62026376
|
|
|
0.710 |
GeneticVariation |
BEFREE |
The rs62026376:C allele associated with increased asthma with hay fever risk has been found to be associated also with decreased expression of the nearby DEXI gene in monocytes.
|
24388013 |
2014 |
rs76043829
|
|
A |
0.710 |
GeneticVariation |
GWASCAT |
Single nucleotide polymorphisms with suggestive evidence for association with asthma with hay fever risk included rs41295115 near IL2RA (OR, 1.28; P = 5 × 10(-7)) and rs76043829 in TNS1 (OR, 1.23; P = 2 × 10(-6)).
|
24388013 |
2014 |
rs76043829
|
|
|
0.710 |
GeneticVariation |
BEFREE |
Single nucleotide polymorphisms with suggestive evidence for association with asthma with hay fever risk included rs41295115 near IL2RA (OR, 1.28; P = 5 × 10(-7)) and rs76043829 in TNS1 (OR, 1.23; P = 2 × 10(-6)).
|
24388013 |
2014 |
rs10197862
|
|
A |
0.700 |
GeneticVariation |
GWASCAT |
Genome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype.
|
24388013 |
2014 |
rs11049300
|
|
G |
0.700 |
GeneticVariation |
GWASCAT |
Genome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype.
|
24388013 |
2014 |
rs12450323
|
|
T |
0.700 |
GeneticVariation |
GWASCAT |
Genome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype.
|
24388013 |
2014 |
rs1438673
|
|
C |
0.700 |
GeneticVariation |
GWASCAT |
Genome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype.
|
24388013 |
2014 |
rs17294280
|
|
G |
0.700 |
GeneticVariation |
GWASCAT |
Genome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype.
|
24388013 |
2014 |
rs1837253
|
|
C |
0.700 |
GeneticVariation |
GWASCAT |
Genome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype.
|
24388013 |
2014 |
rs3853750
|
|
C |
0.700 |
GeneticVariation |
GWASCAT |
Genome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype.
|
24388013 |
2014 |
rs4833095
|
|
T |
0.700 |
GeneticVariation |
GWASCAT |
Genome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype.
|
24388013 |
2014 |
rs6982751
|
|
G |
0.700 |
GeneticVariation |
GWASCAT |
Genome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype.
|
24388013 |
2014 |
rs7009110
|
|
T |
0.700 |
GeneticVariation |
GWASCAT |
At genome-wide significance, we identified 11 independent variants associated with the risk of having asthma with hay fever, including 2 associations reaching this level of significance with allergic disease for the first time: ZBTB10 (rs7009110; odds ratio [OR], 1.14; P = 4 × 10(-9)) and CLEC16A (rs62026376; OR, 1.17; P = 1 × 10(-8)).
|
24388013 |
2014 |