×
Entrez Id:
4846
Gene Symbol:
NOS3
NOS3
0.310
GeneticVariation
disease
BEFREE
Endothelial nitric oxide synthase genotype is associated with pulmonary hypertension severity in left heart failure patients.
29718770
2019
×
Entrez Id:
4843
Gene Symbol:
NOS2
NOS2
0.310
GeneticVariation
disease
BEFREE
DNA samples from 118 patients with HF-PH were genotyped for the NOS3 rs1799983 and NOS2 rs3730017 polymorphisms.
29718770
2019
×
Entrez Id:
100506866
Gene Symbol:
TTN-AS1
TTN-AS1
0.100
GeneticVariation
disease
CLINVAR
×
Entrez Id:
7273
Gene Symbol:
TTN
TTN
0.100
GeneticVariation
disease
CLINVAR
×
Entrez Id:
348
Gene Symbol:
APOE
APOE
0.020
GeneticVariation
disease
BEFREE
Patients with no cardiac impairment had an APOE 4 allele frequency (7.9%) not different from population controls (6.5%, P > .05), while patients with LVF had a significantly higher frequency of APOE 4 (12.8%) than the controls (P < .05, odds ratio = 2.11, 95% confidence interval 1.03 to 4.32).
9787187
1998
×
Entrez Id:
4846
Gene Symbol:
NOS3
NOS3
0.310
Biomarker
disease
CTD_human
Isoproterenol-induced heart failure in the rat is associated with nitric oxide-dependent functional alterations of cardiac function.
19168511
2009
×
Entrez Id:
4306
Gene Symbol:
NR3C2
NR3C2
0.310
Biomarker
disease
CTD_human
Mineralocorticoid receptor is overexpressed in cardiomyocytes of patients with congestive heart failure.
15722665
2005
×
Entrez Id:
4843
Gene Symbol:
NOS2
NOS2
0.310
Biomarker
disease
CTD_human
Isoproterenol-induced heart failure in the rat is associated with nitric oxide-dependent functional alterations of cardiac function.
19168511
2009
×
Entrez Id:
4306
Gene Symbol:
NR3C2
NR3C2
0.310
Biomarker
disease
CTD_human
Ablation of mineralocorticoid receptors in myocytes but not in fibroblasts preserves cardiac function.
21321305
2011
×
Entrez Id:
4306
Gene Symbol:
NR3C2
NR3C2
0.310
Biomarker
disease
BEFREE
Several large clinical studies have demonstrated the important benefit of mineralocorticoid receptor (MR ) antagonists in patients with heart failure, left ventricular dysfunction after myocardial infarction, hypertension or diabetic nephropathy.
21784127
2012
×
Entrez Id:
4846
Gene Symbol:
NOS3
NOS3
0.310
Biomarker
disease
CTD_human
MnSOD protects against COX1-mediated endothelial dysfunction in chronic heart failure.
20304815
2010
×
Entrez Id:
152
Gene Symbol:
ADRA2C
ADRA2C
0.300
Biomarker
disease
CTD_human
Synergistic polymorphisms of beta1- and alpha2C-adrenergic receptors and the risk of congestive heart failure.
12374873
2002
×
Entrez Id:
7422
Gene Symbol:
VEGFA
VEGFA
0.300
Biomarker
disease
CTD_human
Carvedilol modulates the expression of hypoxia-inducible factor-1alpha and vascular endothelial growth factor in a rat model of volume-overload heart failure.
15732037
2005
×
Entrez Id:
156
Gene Symbol:
GRK2
GRK2
0.300
Biomarker
disease
CTD_human
Inhibition of G-protein-coupled Receptor Kinase 2 Prevents the Dysfunctional Cardiac Substrate Metabolism in Fatty Acid Synthase Transgenic Mice.
26670611
2016
×
Entrez Id:
5156
Gene Symbol:
PDGFRA
PDGFRA
0.300
Biomarker
disease
CTD_human
Hypereosinophilic Syndrome as a Rare Cause of Reversible Biventricular Heart Failure.
28347583
2017
×
Entrez Id:
3091
Gene Symbol:
HIF1A
HIF1A
0.300
Biomarker
disease
CTD_human
Carvedilol modulates the expression of hypoxia-inducible factor-1alpha and vascular endothelial growth factor in a rat model of volume-overload heart failure.
15732037
2005
×
Entrez Id:
6659
Gene Symbol:
SOX4
SOX4
0.300
Biomarker
disease
CTD_human
A context-specific cardiac β-catenin and GATA4 interaction influences TCF7L2 occupancy and remodels chromatin driving disease progression in the adult heart.
29394407
2018
×
Entrez Id:
6647
Gene Symbol:
SOD1
SOD1
0.300
Biomarker
disease
CTD_human
MnSOD protects against COX1-mediated endothelial dysfunction in chronic heart failure.
20304815
2010
×
Entrez Id:
7097
Gene Symbol:
TLR2
TLR2
0.300
Biomarker
disease
CTD_human
TLR2 and TLR3 expression as a biomarker for the risk of doxorubicin-induced heart failure.
29959987
2018
×
Entrez Id:
6548
Gene Symbol:
SLC9A1
SLC9A1
0.300
Biomarker
disease
CTD_human
Paradoxical resistance to myocardial ischemia and age-related cardiomyopathy in NHE1 transgenic mice: a role for ER stress?
19027022
2009
×
Entrez Id:
5294
Gene Symbol:
PIK3CG
PIK3CG
0.300
Biomarker
disease
CTD_human
Phosphoinositide 3-kinase gamma-deficient mice are protected from isoproterenol-induced heart failure.
12963636
2003
×
Entrez Id:
4879
Gene Symbol:
NPPB
NPPB
0.300
Biomarker
disease
CTD_human
The effects of atorvastatin (10 mg) on systemic inflammation in heart failure.
16360360
2005
×
Entrez Id:
4878
Gene Symbol:
NPPA
NPPA
0.300
Biomarker
disease
CTD_human
Use of natriuretic peptides for detecting cardiac dysfunction in long-term disease-free breast cancer survivors.
16101196
2005
TNFRSF1A
0.300
Biomarker
disease
CTD_human
The effects of atorvastatin (10 mg) on systemic inflammation in heart failure.
16360360
2005
×
Entrez Id:
4878
Gene Symbol:
NPPA
NPPA
0.300
Biomarker
disease
CTD_human
Mechanisms of sodium retention in heart failure: relation to the renin-angiotensin-aldosterone system.
1647690
1991