×
Entrez Id:
2322
Gene Symbol:
FLT3
FLT3
1.000
CausalMutation
disease
CLINVAR
Validation of ITD mutations in FLT3 as a therapeutic target in human acute myeloid leukaemia.
22504184
2012
×
Entrez Id:
2322
Gene Symbol:
FLT3
FLT3
1.000
CausalMutation
disease
CLINVAR
Variable sensitivity of FLT3 activation loop mutations to the small molecule tyrosine kinase inhibitor MLN518.
15256420
2004
×
Entrez Id:
2322
Gene Symbol:
FLT3
FLT3
1.000
CausalMutation
disease
CLINVAR
Activity of ponatinib against clinically-relevant AC220-resistant kinase domain mutants of FLT3-ITD.
23430109
2013
×
Entrez Id:
2322
Gene Symbol:
FLT3
FLT3
1.000
CausalMutation
disease
CLINVAR
Prospective evaluation of gene mutations and minimal residual disease in patients with core binding factor acute myeloid leukemia.
23321257
2013
×
Entrez Id:
2322
Gene Symbol:
FLT3
FLT3
1.000
CausalMutation
disease
CLINVAR
The importance of relative mutant level for evaluating impact on outcome of KIT, FLT3 and CBL mutations in core-binding factor acute myeloid leukemia.
23783394
2013
×
Entrez Id:
2322
Gene Symbol:
FLT3
FLT3
1.000
CausalMutation
disease
CLINVAR
Mutational landscape of AML with normal cytogenetics: biological and clinical implications.
23261068
2013
×
Entrez Id:
2322
Gene Symbol:
FLT3
FLT3
1.000
CausalMutation
disease
CLINVAR
A phase 2 trial of the FLT3 inhibitor lestaurtinib (CEP701) as first-line treatment for older patients with acute myeloid leukemia not considered fit for intensive chemotherapy.
16857985
2006
×
Entrez Id:
2322
Gene Symbol:
FLT3
FLT3
1.000
CausalMutation
disease
CLINVAR
FLT3 inhibition selectively kills childhood acute lymphoblastic leukemia cells with high levels of FLT3 expression.
15374878
2005
×
Entrez Id:
2322
Gene Symbol:
FLT3
FLT3
1.000
CausalMutation
disease
CLINVAR
Continuing aspirin in the perioperative patient.
22504186
2012
×
Entrez Id:
2322
Gene Symbol:
FLT3
FLT3
1.000
CausalMutation
disease
CLINVAR
The role of kinase inhibitors in the treatment of patients with acute myeloid leukemia.
23714533
2013
×
Entrez Id:
2322
Gene Symbol:
FLT3
FLT3
1.000
CausalMutation
disease
CLINVAR
Sensitivity toward sorafenib and sunitinib varies between different activating and drug-resistant FLT3-ITD mutations.
17889720
2007
×
Entrez Id:
2322
Gene Symbol:
FLT3
FLT3
1.000
CausalMutation
disease
CLINVAR
Prognostic significance of FLT3 mutations in pediatric non-promyelocytic acute myeloid leukemia.
15863200
2005
×
Entrez Id:
2322
Gene Symbol:
FLT3
FLT3
1.000
CausalMutation
disease
CLINVAR
Crenolanib is active against models of drug-resistant FLT3-ITD-positive acute myeloid leukemia.
24046014
2013