Source: CURATED ×
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2
Gene Symbol: A2M
A2M
0.300 Biomarker disease CTD_human Gene Expression Patterns Associated With Histopathology in Toxic Liver Fibrosis. 26396155 2016
Entrez Id: 5244
Gene Symbol: ABCB4
ABCB4
0.360 Biomarker disease CTD_human Effects of Ursodeoxycholate and cholate feeding on liver disease in FVB mice with a disrupted mdr2 P-glycoprotein gene. 8698195 1996
Entrez Id: 5244
Gene Symbol: ABCB4
ABCB4
0.360 Biomarker disease CTD_human Integrin beta6 mRNA increased with fibrosis stage in hepatitis C and was upregulated between 25- and 100-fold in TAA- and BDL-induced cirrhosis, in Mdr2(Abcb4)(-/-) mice and in human end-stage liver disease. alphavbeta6 protein was absent in normal livers and expressed de novo on (activated) bile duct epithelia and transitional hepatocytes. 18221819 2008
Entrez Id: 59
Gene Symbol: ACTA2
ACTA2
0.300 Biomarker disease CTD_human Ascorbic acid suppresses endotoxemia and NF-κB signaling cascade in alcoholic liver fibrosis in guinea pigs: a mechanistic approach. 24239723 2014
Entrez Id: 59
Gene Symbol: ACTA2
ACTA2
0.300 Biomarker disease CTD_human Precision-cut liver slices as a model for the early onset of liver fibrosis to test antifibrotic drugs. 24321339 2014
Entrez Id: 59
Gene Symbol: ACTA2
ACTA2
0.300 Biomarker disease CTD_human MicroRNA-942 mediates hepatic stellate cell activation by regulating BAMBI expression in human liver fibrosis. 30097701 2018
Entrez Id: 148
Gene Symbol: ADRA1A
ADRA1A
0.300 Biomarker disease CTD_human Norepinephrine induces calcium spikes and proinflammatory actions in human hepatic stellate cells. 16782692 2006
Entrez Id: 183
Gene Symbol: AGT
AGT
0.560 Biomarker disease CTD_human Inhibition of cGMP-specific phosphodiesterase type 5 reduces sodium excretion and arterial blood pressure in patients with NaCl retention and ascites. 15613622 2005
Entrez Id: 196
Gene Symbol: AHR
AHR
0.310 Biomarker disease CTD_human AhR and SHP regulate phosphatidylcholine and S-adenosylmethionine levels in the one-carbon cycle. 29416063 2018
Entrez Id: 210
Gene Symbol: ALAD
ALAD
0.500 Biomarker disease CTD_human Characterization of chemically induced liver injuries using gene co-expression modules. 25226513 2014
Entrez Id: 213
Gene Symbol: ALB
ALB
0.400 Biomarker disease CTD_human This study aimed to assess IMA and IMAR as a liver function test and to investigate whether albumin infusion changes IMAR in patients with liver cirrhosis. 21851314 2011
Entrez Id: 213
Gene Symbol: ALB
ALB
0.400 Biomarker disease CTD_human [Apolipoprotein A in patients with alcoholic liver disease]. 17977396 2008
Entrez Id: 203286
Gene Symbol: ANKS6
ANKS6
0.300 Biomarker disease CTD_human ANKS6 is a central component of a nephronophthisis module linking NEK8 to INVS and NPHP3. 23793029 2013
Entrez Id: 405
Gene Symbol: ARNT
ARNT
0.300 Biomarker disease CTD_human Hypoxia-inducible factor activation in myeloid cells contributes to the development of liver fibrosis in cholestatic mice. 22271822 2012
Entrez Id: 408
Gene Symbol: ARRB1
ARRB1
0.300 Biomarker disease CTD_human Gene Expression Patterns Associated With Histopathology in Toxic Liver Fibrosis. 26396155 2016
Entrez Id: 540
Gene Symbol: ATP7B
ATP7B
0.410 Biomarker disease CTD_human Wilson disease (WD) is caused by accumulation of excess copper (Cu) due to a mutation in the gene encoding the liver Cu transporter ATP7B, and is characterized by acute liver failure or cirrhosis and neuronal cell death. 25134866 2014
Entrez Id: 25805
Gene Symbol: BAMBI
BAMBI
0.300 Biomarker disease CTD_human MicroRNA-942 mediates hepatic stellate cell activation by regulating BAMBI expression in human liver fibrosis. 30097701 2018
Entrez Id: 713
Gene Symbol: C1QB
C1QB
0.300 Biomarker disease CTD_human Gene Expression Patterns Associated With Histopathology in Toxic Liver Fibrosis. 26396155 2016
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
0.320 Biomarker disease CTD_human Monocyte chemoattractant protein-1 deficiency does not affect steatosis or inflammation in livers of mice fed a methionine-choline-deficient diet. 20697377 2010
Entrez Id: 1490
Gene Symbol: CCN2
CCN2
0.350 Biomarker disease CTD_human Profibrogenic transforming growth factor-beta/activin receptor-like kinase 5 signaling via connective tissue growth factor expression in hepatocytes. 17657819 2007
Entrez Id: 1490
Gene Symbol: CCN2
CCN2
0.350 Biomarker disease CTD_human Gene Expression Patterns Associated With Histopathology in Toxic Liver Fibrosis. 26396155 2016
Entrez Id: 1490
Gene Symbol: CCN2
CCN2
0.350 Biomarker disease CTD_human Inhibition of connective tissue growth factor by siRNA prevents liver fibrosis in rats. 16652398 2006
Entrez Id: 929
Gene Symbol: CD14
CD14
0.390 Biomarker disease CTD_human Elevated endotoxin levels in non-alcoholic fatty liver disease. 20353583 2010
Entrez Id: 928
Gene Symbol: CD9
CD9
0.300 Biomarker disease CTD_human Gene Expression Patterns Associated With Histopathology in Toxic Liver Fibrosis. 26396155 2016
Entrez Id: 1131
Gene Symbol: CHRM3
CHRM3
0.300 Biomarker disease CTD_human Scopolamine treatment and muscarinic receptor subtype-3 gene ablation augment azoxymethane-induced murine liver injury. 20197374 2010