Source: CURATED ×
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1281
Gene Symbol: COL3A1
COL3A1 		0.310 Biomarker disease CTD_human Serum aminoterminal propeptide of type III procollagen in psoriasis and psoriatic arthritis: relation to liver fibrosis and arthritis. 1880254 1991
Entrez Id: 1281
Gene Symbol: COL3A1
COL3A1 		0.310 Biomarker disease CTD_human Serum aminoterminal propeptide of type III procollagen. A non-invasive test for liver fibrogenesis in methotrexate-treated psoriatics. 2566230 1989
Entrez Id: 5265
Gene Symbol: SERPINA1
SERPINA1 		0.400 Biomarker disease CTD_human We conclude that men with alpha 1-antitrypsin deficiency may be at higher risk for cirrhosis and primary liver cancer. 3485248 1986
Entrez Id: 5244
Gene Symbol: ABCB4
ABCB4 		0.360 Biomarker disease CTD_human Effects of Ursodeoxycholate and cholate feeding on liver disease in FVB mice with a disrupted mdr2 P-glycoprotein gene. 8698195 1996
Entrez Id: 2147
Gene Symbol: F2
F2 		0.400 Biomarker disease CTD_human Vitamin E reduces monocyte tissue factor expression in cirrhotic patients. 10216089 1999
Entrez Id: 2152
Gene Symbol: F3
F3 		0.330 Biomarker disease CTD_human Vitamin E reduces monocyte tissue factor expression in cirrhotic patients. 10216089 1999
Entrez Id: 1281
Gene Symbol: COL3A1
COL3A1 		0.310 Biomarker disease CTD_human The value of amino-terminal propeptide of type III procollagen in routine screening for methotrexate-induced liver fibrosis: a 10-year follow-up. 11167689 2001
Entrez Id: 1268
Gene Symbol: CNR1
CNR1 		0.310 Biomarker disease CTD_human These results implicate anandamide and vascular CB1 receptors in the vasodilated state in advanced cirrhosis and indicate a novel approach for its management. 11433348 2001
Entrez Id: 2321
Gene Symbol: FLT1
FLT1 		0.510 Biomarker disease CTD_human Hypoxia-induced VEGF and collagen I expressions are associated with angiogenesis and fibrogenesis in experimental cirrhosis. 11981751 2002
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		0.400 Biomarker disease CTD_human Hypoxia-induced VEGF and collagen I expressions are associated with angiogenesis and fibrogenesis in experimental cirrhosis. 11981751 2002
Entrez Id: 3569
Gene Symbol: IL6
IL6 		0.400 Biomarker disease CTD_human Interleukin 6/gp130-dependent pathways are protective during chronic liver diseases. 12830005 2003
Entrez Id: 3291
Gene Symbol: HSD11B2
HSD11B2 		0.310 Biomarker disease CTD_human Renal sodium retention in liver cirrhosis, nephrotic syndrome and hypoxia have been linked to 11beta-HSD2 reduced activity. 15199296 2004
Entrez Id: 183
Gene Symbol: AGT
AGT 		0.560 Biomarker disease CTD_human Inhibition of cGMP-specific phosphodiesterase type 5 reduces sodium excretion and arterial blood pressure in patients with NaCl retention and ascites. 15613622 2005
Entrez Id: 5972
Gene Symbol: REN
REN 		0.400 Biomarker disease CTD_human In patients with ascites and cirrhosis, inhibition of PDE5 did not promote natriuresis but led to increased plasma levels of the renin-angiotensin-aldosterone system. 15613622 2005
Entrez Id: 4878
Gene Symbol: NPPA
NPPA 		0.300 Biomarker disease CTD_human Inhibition of cGMP-specific phosphodiesterase type 5 reduces sodium excretion and arterial blood pressure in patients with NaCl retention and ascites. 15613622 2005
Entrez Id: 4313
Gene Symbol: MMP2
MMP2 		0.510 Biomarker disease CTD_human Interleukin-6 protects hepatocytes from CCl4-mediated necrosis and apoptosis in mice by reducing MMP-2 expression. 15763341 2005
Entrez Id: 1269
Gene Symbol: CNR2
CNR2 		0.310 Biomarker disease CTD_human In liver biopsy specimens from patients with active cirrhosis of various etiologies, CB2 receptors were expressed in nonparenchymal cells located within and at the edge of fibrous septa in smooth muscle alpha-actin-positive cells. 15765409 2005
Entrez Id: 1281
Gene Symbol: COL3A1
COL3A1 		0.310 Biomarker disease CTD_human Monitoring patients on methotrexate: hepatic fibrosis not seen in patients with normal serum assays of aminoterminal peptide of type III procollagen. 15787813 2005
Entrez Id: 6696
Gene Symbol: SPP1
SPP1 		0.340 Biomarker disease CTD_human Osteopontin expression in normal and fibrotic liver. altered liver healing in osteopontin-deficient mice. 16221502 2006
Entrez Id: 1490
Gene Symbol: CCN2
CCN2 		0.350 Biomarker disease CTD_human Inhibition of connective tissue growth factor by siRNA prevents liver fibrosis in rats. 16652398 2006
Entrez Id: 1281
Gene Symbol: COL3A1
COL3A1 		0.310 Biomarker disease CTD_human Use of amino terminal type III procollagen peptide (P3NP) assay in methotrexate therapy for psoriasis. 16679477 2006
Entrez Id: 148
Gene Symbol: ADRA1A
ADRA1A 		0.300 Biomarker disease CTD_human Norepinephrine induces calcium spikes and proinflammatory actions in human hepatic stellate cells. 16782692 2006
Entrez Id: 2247
Gene Symbol: FGF2
FGF2 		0.340 Therapeutic disease CTD_human Administration of fibroblast growth factor 2 in combination with bone marrow transplantation synergistically improves carbon-tetrachloride-induced liver fibrosis in mice. 17093919 2007
Entrez Id: 3082
Gene Symbol: HGF
HGF 		0.400 Therapeutic disease CTD_human Effects of hepatotrophic factors on the liver after portacaval shunt in rats with portal hypertension. 17097021 2006
Entrez Id: 3727
Gene Symbol: JUND
JUND 		0.300 Biomarker disease CTD_human JunD is a profibrogenic transcription factor regulated by Jun N-terminal kinase-independent phosphorylation. 17133482 2006